Top 10 Companies in the Cyclodextrin in Pharma Market (2026): Market Leaders Powering Global Pharmaceutical Innovation

MARKET INSIGHTS

The Global cyclodextrin in pharma market size was valued at USD 30.4 million in 2024. The market is projected to grow from USD 32.3 million in 2025 to USD 47.6 million by 2032, exhibiting a CAGR of 6.4% during the forecast period.

Cyclodextrins are cyclic oligosaccharides composed of glucose subunits linked by α-1,4 glycosidic bonds, primarily used in pharmaceutical formulations to enhance drug solubility and stability. These naturally derived molecules are produced through enzymatic conversion of starch and find extensive applications in drug delivery systems, including tablets, capsules, and injectables. The three main types—alpha, beta, and gamma cyclodextrins—along with their derivatives, serve as critical excipients in modern pharmaceuticals.

The market growth is driven by increasing demand for advanced drug formulations and the rising prevalence of poorly water‑soluble drugs, which account for nearly 40% of new chemical entities. While North America and Europe currently dominate production with over 60% market share held by top manufacturers like Wacker and Ashland, China is emerging as a significant production hub with concentrated manufacturing in Shandong and Jiangsu provinces. Recent industry developments include expanding applications in mRNA vaccine formulations and targeted drug delivery systems, further propelling market expansion.

Cyclodextrin in Pharma Market – View in Detailed Research Report

🔟 10. Wacker Chemie AG

Headquarters: Darmstadt, Germany
Key Offering: Alpha, beta, and gamma cyclodextrins for oral, injectable, and biologic formulations

Wacker Chemie AG has long been a pioneer in cyclodextrin technology, providing high‑purity excipients for both conventional and advanced pharmaceutical products. Their extensive production facilities in Europe and North America enable rapid supply to global pharmaceutical companies, ensuring consistent quality and timely delivery.

Sustainability & Growth Initiatives:

• Investment in green enzymatic processes to reduce waste and energy consumption
• Strategic partnership with a Spanish biotech firm to expand beta‑cyclodextrin derivatives
• Commitment to achieving net‑zero emissions by 2050 across manufacturing sites

9️⃣ 9. Roquette Frères

Headquarters: Roquemaure, France
Key Offering: Hydroxypropyl‑beta‑cyclodextrin (HP‑β‑CD) and sulfobutyl ether‑beta‑cyclodextrin (SBE‑β‑CD) for solubility enhancement and drug stabilization

Roquette’s diversified portfolio of modified cyclodextrins positions it as a leader in delivering customized excipients for a wide range of pharmaceutical applications, from oral tablets to complex biologics.

Sustainability & Growth Initiatives:

• Partnership with a major U.S. pharma company to develop novel drug delivery systems
• Investment in renewable energy for production facilities
• Focus on circular economy practices, including recycling of process by‑products

8️⃣ 8. Ashland Global Holdings Inc.

Headquarters: Wilmington, Delaware, USA
Key Offering: Cyclodextrin derivatives for oral, injectable, and biologic formulations, with a strong focus on targeted delivery

Ashland’s global footprint and robust R&D pipeline allow it to supply high‑quality excipients to pharmaceutical giants and emerging generics manufacturers alike.

Sustainability & Growth Initiatives:

• Expansion of production capacity in North America and Asia
• Development of eco‑friendly manufacturing processes
• Strategic alliances with biotech startups for hybrid delivery platforms

7️⃣ 7. Ensuiko Sugar Refining Co., Ltd.

Headquarters: Osaka, Japan
Key Offering: High‑purity beta‑cyclodextrin for oral and injectable formulations

Ensuiko’s expertise in starch conversion and enzymatic processing ensures consistent supply of pharmaceutical‑grade cyclodextrins to the Japanese and global markets.

Sustainability & Growth Initiatives:

• Implementation of water‑recycling systems in production plants
• Investment in research for next‑generation cyclodextrin derivatives
• Collaboration with academic institutions for process optimization

6️⃣ 6. Nihon Shokuhin Kako Co., Ltd.

Headquarters: Tokyo, Japan
Key Offering: Beta‑cyclodextrin for oral and injectable drug delivery

Nihon Shokuhin Kako has a long history of supplying high‑quality excipients to the pharmaceutical industry, with a focus on regulatory compliance and product innovation.

Sustainability & Growth Initiatives:

• Adoption of ISO 14001 environmental management systems
• Development of low‑water‑usage enzymatic processes
• Strategic investment in emerging markets such as India and China

5️⃣ 5. Shandong Xinda Biotechnology Co., Ltd.

Headquarters: Jinan, China
Key Offering: Beta‑cyclodextrin for generic drug formulations

Shandong Xinda’s rapid expansion in production capacity has positioned it as a major supplier of cost‑effective cyclodextrins to the Asian market.

Sustainability & Growth Initiatives:

• Upgrade of manufacturing facilities to meet international quality standards
• Implementation of energy‑efficient production lines
• Collaboration with local universities for talent development

4️⃣ 4. Yunan Yongguang Biotechnology Co., Ltd.

Headquarters: Yunnan, China
Key Offering: Beta‑cyclodextrin for oral and injectable drug delivery

Yunan Yongguang focuses on high‑purity excipients for both domestic and export markets, emphasizing stringent quality control.

Sustainability & Growth Initiatives:

• Integration of renewable energy sources in production
• Development of eco‑friendly purification methods
• Strategic partnerships with international pharma firms

3️⃣ 3. Qufu Tianli Pharmaceutical Excipients Co., Ltd.

Headquarters: Qufu, China
Key Offering: Beta‑cyclodextrin for generic and branded drug formulations

Qufu Tianli’s strong focus on research and development allows it to produce customized cyclodextrin derivatives tailored to specific API requirements.

Sustainability & Growth Initiatives:

• Implementation of green chemistry principles in manufacturing
• Investment in high‑yield enzymatic processes
• Expansion of export capabilities to Southeast Asia

2️⃣ 2. Zibo Qianhui Biological Technology Co., Ltd.

Headquarters: Zibo, China
Key Offering: Beta‑cyclodextrin for oral and injectable formulations

Zibo Qianhui’s extensive production network supports its role as a key supplier of cost‑effective excipients across Asia.

Sustainability & Growth Initiatives:

• Adoption of waste‑reduction technologies in processing
• Investment in renewable energy projects
• Strategic alliances with pharmaceutical contract manufacturers

1️⃣ 1. Mengzhou Huaxing Biotechnology Co., Ltd.

Headquarters: Mengzhou, China
Key Offering: Beta‑cyclodextrin for generic and specialty drug formulations

Mengzhou Huaxing emphasizes quality and compliance, ensuring its products meet global pharmacopeia standards.

Sustainability & Growth Initiatives:

• Implementation of ISO 9001 and ISO 14001 standards
• Development of low‑energy manufacturing processes
• Expansion of R&D for advanced cyclodextrin derivatives

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Outlook: The Future of Cyclodextrin in Pharma Market

The cyclodextrin market is poised for sustained growth, driven by increasing demand for solubility enhancement in oral, injectable, and biologic drug products. Technological advancements in modified cyclodextrins, coupled with strategic partnerships and expansion into emerging markets, are expected to reinforce the market’s trajectory toward its projected USD 47.6 million valuation by 2032.

Future Trends Shaping the Market

• Emergence of advanced derivatives such as SBE‑β‑CD with superior safety profiles for parenteral use
• Integration of cyclodextrins with nanoparticles and dendrimers to enhance drug loading and targeted delivery
• Growing adoption of green chemistry approaches to reduce environmental impact and lower production costs
• Expansion of local manufacturing capabilities in Asia‑Pacific to meet rising demand for generic and specialty pharmaceuticals
• Increased regulatory focus on safety and quality, driving innovation in formulation and characterization