Top 10 Companies in the 2,4-Dichloro-5-Sulfamoylbenzoic Acid Market (2025): Pharmaceutical Intermediates Leaders Powering Global Drug Manufacturing

In Business Insights
July 03, 2025

The Global 2,4-Dichloro-5-Sulfamoylbenzoic Acid Market was valued at USD 28.7 Million in 2024 and is projected to reach USD 39.2 Million by 2032, growing at a Compound Annual Growth Rate (CAGR) of 4.1% during the forecast period (2024-2032). This pharmaceutical intermediate is experiencing steady demand growth due to its critical role in the synthesis of frusemide (furosemide) – a widely prescribed loop diuretic medication for treating hypertension and edema.

With increasing global prevalence of cardiovascular and renal disorders, pharmaceutical manufacturers are scaling up production of essential medications, driving demand for high-purity chemical intermediates. This analysis profiles the Top 10 Companies in the 2,4-Dichloro-5-Sulfamoylbenzoic Acid Market – a strategic mix of specialized chemical manufacturers and pharmaceutical intermediaries ensuring reliable global supply.

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2,4-Dichloro-5-Sulfamoylbenzoic Acid Market – View in Detailed Research Report


🔟 1. Dharamsi Morarji Chemical Co. Ltd.

Headquarters: Mumbai, India
Key Offering: 98-99.5% Purity Grades, Pharma Intermediates

Established in 1919, Dharamsi Morarji has evolved into one of India’s most reputable manufacturers of pharmaceutical intermediates. The company operates dedicated GMP-compliant facilities producing 2,4-Dichloro-5-Sulfamoylbenzoic Acid with strict quality controls for global pharmaceutical customers.

Manufacturing Capabilities:

  • Current production capacity of 1,500 metric tons annually
  • Advanced chlorination and purification technology
  • Direct supply agreements with major generic drug manufacturers

9️⃣ 2. Triveni Chemicals

Headquarters: Vadodara, India
Key Offering: Technical Grade (95-98%) and Pharmaceutical Grade (99%+)

Triveni Chemicals specializes in halogenated organic compounds with particular expertise in chloro-sulfonation reactions. Their optimized production process delivers consistent quality 2,4-Dichloro-5-Sulfamoylbenzoic Acid with minimal byproducts.

Recent Developments:

  • Capacity expansion completed in Q3 2023
  • Implemented new quality control protocols meeting EP/JP standards
  • Enhanced safety systems for handling chlorinated compounds

8️⃣ 3. Anant Pharmaceuticals

Headquarters: Hyderabad, India
Key Offering: High-Purity Pharma Intermediates (99.5% HPLC)

Anant has positioned itself as a preferred supplier for regulated markets, with their 2,4-Dichloro-5-Sulfamoylbenzoic Acid widely used in formulation development and commercial production of diuretic medications.

Quality Assurance:

  • ISO 9001:2015 certified manufacturing processes
  • Regular audits by global pharmaceutical companies
  • Validated analytical methods for impurity profiling

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2,4-Dichloro-5-Sulfamoylbenzoic Acid Market – View in Detailed Research Report


7️⃣ 4. Cinchona Biosciences Pvt. Ltd.

Headquarters: Chennai, India
Key Offering: Ultra-High Purity (>99.7%) Grades, Custom Research Quantities

Cinchona combines chemical synthesis expertise with advanced process engineering to produce premium quality 2,4-Dichloro-5-Sulfamoylbenzoic Acid. The company serves both commercial manufacturers and research institutions.

Technical Advantages:

  • Patented crystallization process for superior purity
  • Capability to produce isotopes for research applications
  • Closed-loop manufacturing system for environmental compliance

6️⃣ 5. Sai Carbohydrates

Headquarters: Visakhapatnam, India
Key Offering: Cost-Competitive Intermediate, Large Volume Supply

Sai Carbohydrates operates one of India’s highest volume production lines for 2,4-Dichloro-5-Sulfamoylbenzoic Acid, benefiting from integrated raw material sourcing and economies of scale.

Production Highlights:

  • Dedicated 1,200 MT/year manufacturing facility
  • Full backward integration with key precursors
  • Strategic partnerships with domestic pharmaceutical manufacturers

5️⃣ 6. Shanghai Yifei Biotechnology

Headquarters: Shanghai, China
Key Offering: GMP-Certified Intermediates, Contract Manufacturing

This rapidly growing Chinese manufacturer has become a key supplier of 2,4-Dichloro-5-Sulfamoylbenzoic Acid for Asian pharmaceutical companies, with expanding capacity and quality systems.

Market Position:

  • Preferred supplier for Chinese API manufacturers
  • Competitive pricing in the Asia-Pacific region
  • Increasing regulatory compliance for export markets

4️⃣ 7. Shandong Chuangying Chemical

Headquarters: Jinan, China
Key Offering: Technical and Pharma-Grade Products

Chuangying benefits from proximity to China’s chemical industry clusters, ensuring stable raw material availability. The company supplies both pharmaceutical companies and research institutions.

Facility Features:

  • 600 MT annual nameplate capacity
  • Flexible batch sizes for developmental quantities
  • Specialized containment for handling reactive intermediates

3️⃣ 8. Hubei Norna Technology

Headquarters: Wuhan, China
Key Offering: Research-Grade Reference Standards

Norna Technology has developed particular expertise in producing certified reference materials of 2,4-Dichloro-5-Sulfamoylbenzoic Acid for analytical and regulatory applications.

Quality Specifications:

  • HPLC purity up to 99.95% for reference standards
  • Full characterization of all impurities
  • Stability studies supporting long-term storage

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2,4-Dichloro-5-Sulfamoylbenzoic Acid Market – View in Detailed Research Report


2️⃣ 9. Toronto Research Chemicals

Headquarters: Toronto, Canada
Key Offering: Analytical Standards, Research Quantities

While not a commercial-scale producer, TRC plays a vital role as a supplier of certified analytical standards for pharmaceutical testing and method validation.

Scientific Contributions:

  • Certified reference materials with complete documentation
  • Stable isotope-labeled compounds for research
  • Supports pharmaceutical analytical method development

1️⃣ 10. BOC Sciences

Headquarters: Shirley, NY, USA
Key Offering: Custom Synthesis, Development Quantities

BOC Sciences serves the North American pharmaceutical sector with reliable supply of 2,4-Dichloro-5-Sulfamoylbenzoic Acid for drug development and small-scale commercial needs.

Customer Value:

  • Flexible production scale from grams to kilograms
  • Regulatory documentation packages for FDA submissions
  • Technical support for process development

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2,4-Dichloro-5-Sulfamoylbenzoic Acid Market – View in Detailed Research Report


🌍 Market Outlook: Sustained Growth in Cardiovascular Therapeutics

The market for 2,4-Dichloro-5-Sulfamoylbenzoic Acid remains closely tied to the pharmaceutical industry’s need for reliable intermediates for essential medications. As healthcare systems worldwide emphasize affordable treatments, the demand for this critical building block continues to grow.

📈 Key Market Drivers:

  • Increasing global prevalence of hypertension and edema conditions
  • Ongoing demand for generic frusemide formulations
  • Pharmaceutical companies diversifying API sourcing strategies
  • Process innovations improving yields and purity levels

⚠️ Industry Challenges:

  • Environmental regulations on chlorination processes
  • Volatility in raw material (benzene derivatives) pricing
  • Increasing purity expectations from global pharmacopeias
  • Logistical complexities in the pharmaceutical supply chain

Get Full Report Here:
2,4-Dichloro-5-Sulfamoylbenzoic Acid Market – View in Detailed Research Report

The vendors profiled above form the essential supply backbone for this critical pharmaceutical intermediate, enabling the manufacture of life-saving medications worldwide.