The Global 2-Acetylbutyrolactone Market was valued at US$ 24 Million in 2024 and is projected to reach US$ 32.5 Million by 2032, growing at a Compound Annual Growth Rate (CAGR) of 4.5% during the forecast period (2024-2032). This critical chemical intermediate (CAS 517-23-7) serves as a key building block for vitamin B1 synthesis and pharmaceutical applications, with expanding uses across specialty chemicals and high-value manufacturing sectors.
As global demand for chiral compounds and pharmaceutical precursors intensifies, leading producers are investing in advanced synthesis technologies and purity enhancements. This analysis profiles the Top 10 Companies in the 2-Acetylbutyrolactone Market—showcasing their production capabilities, technical expertise, and strategic positioning in this high-growth specialty chemicals segment.
🔟 1. Zhejiang Realsun Chemical Co., Ltd.
Headquarters: Taizhou, Zhejiang, China
Key Offering: Standard (≥98%) and high-purity (≥99%) grades
As the market share leader, Realsun Chemical commands approximately 30% of global 2-acetylbutyrolactone production. The company’s continuous catalytic oxidation process achieves industry-leading 92% conversion efficiency while maintaining competitive production costs.
Capacity Highlights:
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8,000 metric tons annual production capacity
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Strategic partnerships with three top vitamin B1 producers
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REACH and ISO 9001 certified manufacturing facilities
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9️⃣ 2. MYJ Chemical Co., Ltd.
Headquarters: Shanghai, China
Key Offering: Pharmaceutical-grade (99.7% purity)
Specializing in high-purity synthesis, MYJ Chemical has become the preferred supplier for European pharmaceutical manufacturers requiring ultra-low impurities. Their molecular distillation technology achieves residual solvent levels below 50 ppm.
Quality Standards:
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Dedicated cGMP production line
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Validated USP/EP analytical methods
8️⃣ 3. Hefei TNJ Chemical Industry Co., Ltd.
Headquarters: Hefei, Anhui, China
Key Offering: Industrial and laboratory reagent grades
TNJ Chemical operates one of China’s most vertically integrated γ-butyrolactone derivative facilities, with domestic production of key precursors including acetylene and maleic anhydride. Their cost structure supports bulk chemical applications.
Production Metrics:
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5,000 metric tons annual capacity at 85% utilization
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Closed-loop solvent recovery system reduces production costs by 18%
7️⃣ 4. Zhengzhou Alfa Chemical Co., Ltd.
Headquarters: Zhengzhou, Henan, China
Key Offering: Custom purity specifications (95-99.9%)
Alfa Chemical distinguishes itself through flexible batch production capabilities catering to specialty chemical formulators. Their patented low-temperature synthesis method reduces energy consumption by 40% versus conventional processes.
Technical Advantages:
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Pilot plant for derivative development
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Halal/Kosher certification available for food/pharma applications
Download FREE Sample Report: 2-Acetylbutyrolactone Market – View in Detailed Research Report
6️⃣ 5. Taizhou Yanling Fine Chemicals Co., Ltd.
Headquarters: Taizhou, Jiangsu, China
Key Offering: Technical and USP-compliant grades
With 15 years of γ-butyrolactone derivatives expertise, Yanling Chemicals serves customers in 22 countries through strategically located distribution hubs. Their in-house QC laboratory performs full GC/MS characterization on every production batch.
Market Position:
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20% export share among Chinese producers
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Warehousing facilities in Rotterdam and Houston
5️⃣ 6. Daicel Corporation
Headquarters: Osaka, Japan
Key Offering: Electronic-grade (99.95% purity)
Daicel applies pharmaceutical production standards to high-tech applications, delivering 2-acetylbutyrolactone with sub-ppb metal impurities for semiconductor manufacturing. Their proprietary molecular distillation technology achieves industry-leading purity levels.
Technical Capabilities:
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Class 100 cleanroom packaging
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SEMI-standard quality certifications
4️⃣ 7. Hangzhou Dayangchem Co., Ltd.
Headquarters: Hangzhou, Zhejiang, China
Key Offering: Vitamin B1 synthesis grade
As a specialist in vitamin precursors, Dayangchem supplies 2-acetylbutyrolactone to leading thiamine manufacturers globally. Their continuous hydrogenation process delivers superior batch-to-batch consistency critical for pharmaceutical production.
Regulatory Compliance:
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EDMF and CEP documentation support
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FDA-inspected manufacturing site
3️⃣ 8. Finetech Industry Limited
Headquarters: Hong Kong
Key Offering: Research quantities (100g-10kg)
Finetech serves the scientific community with laboratory-scale 2-acetylbutyrolactone supply and one of the most comprehensive inventories of γ-butyrolactone derivatives for experimental applications.
Research Services:
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Custom isotopic labeling (13C, deuterated)
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Full spectral data with NMR/GC-MS characterization
2️⃣ 9. Shanghai UCHEM Inc.
Headquarters: Shanghai, China
Key Offering: Bulk industrial grade
UCHEM’s large-scale production allows cost-efficient supply for industrial applications. Their hybrid facility combines traditional chemical synthesis with emerging biocatalytic conversion technologies.
Capacity Highlights:
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12,000 metric tons nameplate capacity
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Zero-liquid discharge wastewater treatment system
1️⃣ 10. Capot Chemical Co., Ltd.
Headquarters: Hangzhou, Zhejiang, China
Key Offering: Specialty and chiral derivatives
Capot Chemical focuses on high-value 2-acetylbutyrolactone applications, including enantiomerically pure forms for asymmetric synthesis. Their contract research services support novel derivative development.
Advanced Capabilities:
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Chiral separation via preparative HPLC
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Synthetic route development for patent applications
Read Full Report: 2-Acetylbutyrolactone Market – View in Detailed Research Report
🧪 Market Outlook: Evolving Applications Drive Growth
The 2-acetylbutyrolactone market is transitioning from traditional vitamin synthesis to advanced applications in electronics, specialty chemicals, and biocatalysis. Producers are responding with tailored molecular properties and sustainable manufacturing innovations.
📊 Key Market Trends:
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Pharmaceutical segment growing at 5.8% CAGR through 2032
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Electronic-grade demand expanding at 7.2% annually
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Continuous process adoption improving yields by 15-20%
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Green chemistry initiatives reducing VOC emissions by 30%
Read Full Report: 2-Acetylbutyrolactone Market – View in Detailed Research Report
These industry leaders demonstrate how specialized chemical manufacturing combines scientific expertise with strategic vision to serve evolving high-value applications across multiple industries.
