Top 10 Companies in the Global Retinoic Acid Market (2025): Industry Leaders Transforming Dermatology and Medicine

In Business Insights
June 12, 2025

The Global Retinoic Acid Market was valued at USD 1.23 Billion in 2024 and is projected to reach USD 1.67 Billion by 2030, growing at a Compound Annual Growth Rate (CAGR) of 5.2% during the forecast period (2024–2030). The United States market alone accounted for USD 345 million in 2024, with expected growth to USD 456 million by 2030 at a CAGR of 4.7%. This robust expansion is fueled by rising demand for anti-aging skincare solutions, acne treatments, and expanding therapeutic applications in oncology and stem cell research.

As medical science continues to unlock the potential of this vitamin A metabolite, pharmaceutical companies and research institutions are investing heavily in retinoic acid formulation technologies. This article profiles the Top 10 Companies in the Retinoic Acid Market—from established pharmaceutical giants to specialized biochemical manufacturers shaping the future of dermal and medical applications.


🔟 1. LGM PHARMA

Headquarters: Santa Ana, California, USA
Key Offering: Pharmaceutical-grade retinoic acid API

LGM Pharma is a leading supplier of active pharmaceutical ingredients (APIs), including high-purity retinoic acid for pharmaceutical formulations. The company serves global pharmaceutical manufacturers with GMP-compliant compounds.

Key Developments:

  • FDA-approved manufacturing facilities

  • Custom synthesis services for retinoic acid derivatives

Download FREE Sample Report: Global Retinoic Acid Market – View in Detailed Research Report


9️⃣ 2. GYMA Laboratories of America

Headquarters: Miami, Florida, USA
Key Offering: Cosmetic-grade retinoic acid formulations

GYMA specializes in advanced dermatological ingredients, providing stabilized retinoic acid solutions for anti-aging and acne treatment formulations used by major skincare brands worldwide.

Key Developments:

  • Patented encapsulation technology for improved skin penetration

  • Compliance with global cosmetic regulations


8️⃣ 3. GENEMED SYNTHESIS INC.

Headquarters: South San Francisco, California, USA
Key Offering: Research-grade retinoic acid for laboratories

Genemed Synthesis provides high-purity retinoic acid compounds tailored for research applications in stem cell differentiation, cancer studies, and developmental biology research.

Key Developments:

  • ISO 9001 certified production

  • Specialized formulations for in vitro applications


7️⃣ 4. IMCOPHARMA

Headquarters: Anhui, China
Key Offering: Pharmaceutical intermediate retinoic acid

IMCOPHARMA is a major Chinese producer of retinoic acid intermediates and APIs, supplying both domestic and international pharmaceutical manufacturers.

Key Developments:

  • Large-scale production capabilities

  • Strategic partnerships with European and American pharma companies

Download FREE Sample Report: Global Retinoic Acid Market – View in Detailed Research Report


6️⃣ 5. Huapont Pharmaceutical

Headquarters: Chongqing, China
Key Offering: Retinoic acid API and finished dosage forms

Huapont is a vertically integrated pharmaceutical company developing both retinoic acid APIs and finished dermatological products, including tretinoin creams for acne treatment.

Key Developments:

  • Diverse product portfolio including oral and topical formulations

  • GMP-certified manufacturing facilities


5️⃣ 6. JSN Chemical

Headquarters: Cary, North Carolina, USA
Key Offering: High-purity retinoic acid for research

JSN Chemical supplies analytical standards and research chemicals to academic institutions and pharmaceutical R&D departments, including various retinoic acid isomers.

Key Developments:

  • Specialized in rare retinoic acid derivatives

  • Documentation for research compliance


4️⃣ 7. Horlden Bio-Tech

Headquarters: Guangzhou, China
Key Offering: Bulk retinoic acid for cosmetic applications

Horlden Bio-Tech manufactures cosmetic-grade retinoic acid used in professional skincare products and OTC topical treatments across Asia and Europe.

Key Developments:

  • Focus on stable retinoic acid formulations

  • Custom concentration blending services


3️⃣ 8. Bio-Rad Laboratories

Headquarters: Hercules, California, USA
Key Offering: Research antibodies and retinoic acid solutions

Bio-Rad provides analytical tools and reagents for retinoic acid research, including antibodies, ELISA kits, and standardized solutions for laboratory use.

Key Developments:

  • Comprehensive research solutions for retinoic acid pathway studies

  • Validated products for reproducible research


2️⃣ 9. Sun Pharmaceutical Industries Ltd.

Headquarters: Mumbai, India
Key Offering: Prescription retinoid medications

As one of India’s largest pharmaceutical companies, Sun Pharma markets multiple FDA-approved retinoic acid-based drugs for acne and photoaging treatment globally.

Key Developments:

  • Extensive clinical research on retinoid formulations

  • Global distribution network for dermatological products


1️⃣ 10. Tara Innovations LLC

Headquarters: Woburn, Massachusetts, USA
Key Offering: Novel retinoic acid delivery systems

Tara Innovations specializes in advanced drug delivery technologies for retinoids, developing liposomal and nanoparticle formulations that enhance efficacy while reducing irritation.

Key Developments:

  • Patented delivery technologies

  • Partnerships with cosmetic and pharmaceutical companies

Get Full Report Here: Global Retinoic Acid Market – View in Detailed Research Report


🔬 Outlook: Retinoic Acid’s Expanding Therapeutic Horizons

The retinoic acid market is witnessing transformative growth, driven not only by traditional dermatological applications but also by emerging therapeutic uses in oncology, immunology, and regenerative medicine.

📈 Key Market Trends:

  • Development of next-generation retinoic acid derivatives with improved safety profiles

  • Expansion into combination therapies for enhanced efficacy

  • Growing demand for personalized retinoid formulations

  • Increasing adoption in emerging markets due to rising skincare awareness

Get Full Report Here: Global Retinoic Acid Market – View in Detailed Research Report

The companies profiled above are at the forefront of retinoic acid innovation, developing products that span from cosmetic ingredients to life-saving medications, transforming patient care across multiple therapeutic areas.