The Global Methylidenesuccinic Acid Market was valued at USD 180 Million in 2024 and is projected to reach USD 245 Million by 2030, growing at a Compound Annual Growth Rate (CAGR) of 5.3% during the forecast period (2024–2030). This growth is fueled by increasing demand for sustainable chemical solutions, expansion into new industrial applications, and the global shift toward bio-based raw materials.

As industries transition toward greener chemistry, methylidenesuccinic acid (commonly known as itaconic acid) has emerged as a versatile platform chemical with applications ranging from biopolymers to pharmaceutical intermediates. In this analysis, we profile the Top 10 Companies in the Methylidenesuccinic Acid Industry—the innovators and production leaders shaping this growing market.

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🔟 1. Kehai Biochemistry

Headquarters: Shandong, China
Key Offering: High-Purity Itaconic Acid (99.5% Grade)

As China’s largest producer of fermentation-based itaconic acid, Kehai Biochemistry operates advanced production facilities with an annual capacity exceeding 20,000 metric tons. The company supplies both domestic and international markets with bio-based chemical solutions.

Key Advantages:

• Pioneer in continuous fermentation technology
• Strategic partnerships with global chemical distributors
• ISO 9001 certified production facilities

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Global Methylidenesuccinic Acid Market – View in Detailed Research Report

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9️⃣ 2. Guoguang Biochemistry

Headquarters: Zhejiang, China
Key Offering: Pharmaceutical-Grade Itaconic Acid

Specializing in high-purity formulations, Guoguang Biochemistry has emerged as a preferred supplier for specialty chemical and pharmaceutical applications, with particular strength in the Asian market.

Production Highlights:

• Annual capacity of 12,000 metric tons
• GMP-certified production lines
• Vertically integrated fermentation process

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8️⃣ 3. Huaming Biochemistry

Headquarters: Shandong, China
Key Offering: Industrial-Grade Itaconic Acid

With multiple production facilities across China, Huaming Biochemistry supplies cost-effective itaconic acid solutions to bulk chemical processors and industrial manufacturers.

Market Position:

• Leading exporter to European polymer markets
• Strategic focus on derivative development
• Strong logistics network in Asia-Pacific

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7️⃣ 4. Alpha Chemika

Headquarters: Maharashtra, India
Key Offering: Synthetic & Bio-Based Itaconic Acid

Alpha Chemika serves as a crucial bridge between Asian producers and global markets, offering multiple grades of methylidenesuccinic acid to diverse industrial sectors.

Value Proposition:

• Robust quality control systems
• Technical support for formulation development
• Customized packaging solutions

Download FREE Sample Report:
Global Methylidenesuccinic Acid Market – View in Detailed Research Report

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6️⃣ 5. Zhongshun Science & Technology

Headquarters: Jiangsu, China
Key Offering: Specialty & Modified Itaconic Acid Derivatives

This technology-driven company focuses on developing advanced itaconic acid formulations for specialized applications in coatings, adhesives, and composite materials.

Innovation Focus:

• 15+ patent applications in derivative chemistries
• Collaborative R&D with academic institutions
• Specialty formulations for niche applications

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5️⃣ 6. Qingdao Kehai Biochemistry

Headquarters: Shandong, China
Key Offering: Bulk Itaconic Acid for Industrial Applications

With fermentation facilities strategically located near raw material sources, Qingdao Kehai delivers cost-competitive bio-based chemicals to industrial buyers worldwide.

Operational Strengths:

• Backward integration with agricultural feedstock
• Automated production monitoring systems
• Sustainable water recycling processes

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4️⃣ 7. Itaconix Corporation

Headquarters: New Hampshire, USA
Key Offering: Specialty Polymers from Itaconic Acid

Itaconix stands out as a Western leader in developing high-value bio-based polymers and performance materials derived from itaconic acid chemistry.

Technology Edge:

• Proprietary polymerization technologies
• Focus on sustainable material solutions
• Strong patent portfolio in green chemistry

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3️⃣ 8. Jinju Huakang Biological Technology

Headquarters: Zhejiang, China
Key Offering: Food-Grade Itaconic Acid

Specializing in high-purity biochemicals for food and pharmaceutical applications, Jinju Huakang has developed specialized fermentation processes for sensitive applications.

Quality Focus:

• Food safety certifications (HACCP, FSSC 22000)
• Traceability throughout production chain
• Custom purification processes

Download FREE Sample Report:
Global Methylidenesuccinic Acid Market – View in Detailed Research Report

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2️⃣ 9. Iwata Chemical Co.

Headquarters: Tokyo, Japan
Key Offering: High-Purity Itaconic Acid for Research & Specialty Applications

This Japanese specialty chemical company serves advanced research institutions and high-tech industries with precision-grade biochemicals.

Specialization:

• Microbial fermentation expertise
• Nanoscale purification techniques
• Technical application support

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1️⃣ 10. Sigma-Aldrich (Merck KGaA)

Headquarters: Darmstadt, Germany
Key Offering: Laboratory-Grade Itaconic Acid & Derivatives

As part of the Merck Group, Sigma-Aldrich supplies high-purity chemicals to global research institutions and pharmaceutical companies exploring itaconic acid applications.

Research Focus:

• Ultra-high purity standards
• Broad catalog of derivatives
• Global distribution network

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🌍 Market Outlook: Bio-Based Chemicals Gaining Momentum

The methylidenesuccinic acid market is undergoing significant transformation as industries increasingly adopt sustainable chemical alternatives. Key trends include:

📈 Market Shaping Developments:

• Expanding applications in biopolymers and sustainable materials
• Advances in fermentation technology improving yields
• Growing demand from emerging economies
• Increasing regulatory support for bio-based chemicals

Get Full Report Here:
Global Methylidenesuccinic Acid Market – View in Detailed Research Report

The companies profiled represent the vanguard of a chemical industry moving toward sustainable, bio-based solutions—transforming industrial chemistry while reducing environmental impact.