The Global Cosmetic Grade Polydeoxyribonucleotide (PDRN) Market was valued at USD 26 million in 2023 and is projected to reach USD 662.50 million by 2032, growing at a Compound Annual Growth Rate (CAGR) of 43.30% during the forecast period (2023-2032). This remarkable expansion stems from increasing demand for advanced anti-aging solutions, scar treatments, and regenerative therapies across dermatological and aesthetic applications.

PDRN has emerged as a breakthrough ingredient in cosmetic science, derived from salmon DNA to promote skin repair and collagen synthesis. This report profiles the Top 10 Companies in the Cosmetic Grade PDRN Industry – biotech innovators and skincare specialists transforming medical aesthetics and dermatology.

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🔟 1. HTL Biotechnology

Headquarters: Paris, France
Key Offering: PDRN extracts for dermo-cosmetics

A European pioneer in marine-derived biomaterials, HTL Biotechnology specializes in high-purity PDRN formulations. Their patented extraction process maintains DNA integrity for optimal bioavailability in skincare applications.

Key Innovations:

• GMP-certified production facilities
• Sustainable sourcing from controlled fisheries
• Clinical-grade purity standards

Download FREE Sample Report: Global Cosmetic Grade Polydeoxyribonudeotide (PDRN) Market – View in Detailed Research Report

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9️⃣ 2. ReaLi Tide Biological

Headquarters: Guangzhou, China
Key Offering: Injectable PDRN solutions

ReaLi Tide has established itself as China’s leading PDRN supplier, providing medical-grade DNA extracts to aesthetic clinics and skincare brands across Asia.

Key Innovations:

• High-concentration formulations
• Advanced sterilization technology

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8️⃣ 3. PharmaResearch Co., Ltd.

Headquarters: Seoul, South Korea
Key Offering: PDRN for mesotherapy applications

This Korean biotech leader develops premium PDRN products specifically formulated for dermatological procedures and professional skincare treatments.

Key Innovations:

• Patented low-temperature processing
• Enhanced collagen-stimulating formulas

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7️⃣ 4. Humedix

Headquarters: Seoul, South Korea
Key Offering: PDRN hydrogel wound dressings

Humedix combines PDRN with advanced delivery systems to create effective solutions for scar reduction and skin regeneration in clinical settings.

Key Innovations:

• FDA-cleared wound care products
• Controlled-release technology

Download FREE Sample Report: Global Cosmetic Grade Polydeoxyribonudeotide (PDRN) Market – View in Detailed Research Report

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6️⃣ 5. Ruijiming Biological

Headquarters: Xi’an, China
Key Offering: Pharmaceutical-grade PDRN

Ruijiming supplies high-purity PDRN to medical and cosmetic manufacturers, adhering to strict international quality standards for DNA-based ingredients.

Key Innovations:

• Multi-step purification process
• Custom molecular weights available

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5️⃣ 6. HENGYU BIOPH

Headquarters: Shanghai, China
Key Offering: Raw PDRN materials

HENGYU BIOPH provides cost-effective PDRN solutions through vertically integrated production, serving global skincare brands with consistent quality.

Key Innovations:

• Large-scale manufacturing
• ISO-certified facilities

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4️⃣ 7. Mastelli

Headquarters: Sanremo, Italy
Key Offering: Medical-grade PDRN

Mastelli combines Italian pharmaceutical expertise with innovative PDRN formulations for both aesthetic medicine and advanced skincare applications.

Key Innovations:

• Stabilization technology
• EU regulatory compliance

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3️⃣ 8. Dongkook

Headquarters: Seoul, South Korea
Key Offering: PDRN topical formulations

Dongkook Pharmaceuticals specializes in transdermal PDRN delivery systems optimized for both professional treatments and consumer skincare products.

Key Innovations:

• Enhanced skin penetration technology
• Clinical validation studies

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2️⃣ 9. BR PHARM

Headquarters: Seoul, South Korea
Key Offering: Ready-to-use PDRN ampoules

BR PHARM provides standardized PDRN solutions for aesthetic clinics and skincare brands, ensuring consistent potency and stability.

Key Innovations:

• Precision dosing systems
• Multi-active formulations

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1️⃣ 10. BMI KOREA

Headquarters: Seoul, South Korea
Key Offering: Clinical-grade PDRN

BMI KOREA develops PDRN solutions specifically designed for professional dermatological treatments and medical aesthetic procedures.

Key Innovations:

• Procedure-specific formulations
• Medical device standards

Get Full Report Here: Global Cosmetic Grade Polydeoxyribonudeotide (PDRN) Market – View in Detailed Research Report

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🌍 Market Outlook: The Future of PDRN in Dermatology

The cosmetic grade PDRN sector represents a convergence of biotechnology and aesthetic medicine, with DNA-based therapies establishing new standards in skin health and regeneration.

📈 Market Trends to Watch:

• Expansion into combination therapies with growth factors
• Increasing adoption in professional skin rejuvenation treatments
• Growing demand for clinical-grade skincare ingredients
• Advancements in DNA extraction and stabilization technologies

Get Full Report Here: Global Cosmetic Grade Polydeoxyribonudeotide (PDRN) Market – View in Detailed Research Report

The companies profiled represent the vanguard of the PDRN revolution, transforming dermatological science with innovative DNA-based solutions that bridge aesthetics and regenerative medicine.