Top 10 Companies in the Trehalose Industry (2025): Market Leaders Powering Global Biomolecule Innovation

In Business Insights
June 05, 2025


The Global Trehalose Market was valued at US$ 180.6 million in 2024 and is projected to reach US$ 228.1 million by 2030, growing at a Compound Annual Growth Rate (CAGR) of 3.4% during the forecast period (2024–2030). This stable growth is driven by expanding applications in food preservation, pharmaceutical formulations, and premium skincare products due to trehalose’s unique properties as a natural stabilizer and protectant.

As global industries increasingly prioritize natural and functional ingredients, trehalose has emerged as a versatile biomolecule with cross-sector potential. This analysis profiles the Top 10 Companies in the Trehalose Industry—market leaders who are driving production innovation, expanding applications, and shaping the future of this specialized carbohydrate.


🔟 1. Hayashibara Co., Ltd.

Headquarters: Okayama, Japan
Key Offering: Pharmaceutical-grade trehalose, Food ingredients

Hayashibara remains the global pioneer and market leader in trehalose production, holding critical patents for enzymatic production methods. The company supplies ultra-pure trehalose to multinational pharmaceutical companies and premium food manufacturers worldwide.

Innovation Highlights:

  • Pioneered cost-effective enzymatic conversion technology

  • Exclusive supplier to 70% of global biopharmaceutical applications

  • Ongoing R&D in vaccine stabilization formulations

Download FREE Sample Report: Trehalose Market – View in Detailed Research Report


9️⃣ 2. Meihua Holdings Group Co., Ltd.

Headquarters: Hebei, China
Key Offering: Industrial-scale trehalose production

Meihua has rapidly become China’s dominant trehalose manufacturer, leveraging the country’s extensive starch supply chain for competitive production. The company supplies both domestic and international markets across multiple industries.

Innovation Highlights:

  • 300% production capacity expansion in 2022-2024

  • Strategic alliances with major Asian food processors


8️⃣ 3. Sinozyme Biotechnology Co., Ltd.

Headquarters: Zhejiang, China
Key Offering: Enzyme-optimized trehalose solutions

Sinozyme has established itself as a leading Asian producer through proprietary enzyme technologies that enhance yield and purity. The company serves both China’s booming domestic market and international clients.

Innovation Highlights:

  • Proprietary enzyme cocktails reducing production costs by 18%

  • Expanding into high-margin biopharmaceutical applications


7️⃣ 4. Lianmeng Chemical Group

Headquarters: Shandong, China
Key Offering: Cost-competitive industrial trehalose

Lianmeng Chemical has carved a niche as a reliable volume supplier to Asia’s food processing and industrial sectors. The company emphasizes automated production and consistent quality.

Innovation Highlights:

  • 95% automated production facilities

  • Custom-formulated blends for specific applications


6️⃣ 5. Shandong Fuyang Biotechnology Co., Ltd.

Headquarters: Shandong, China
Key Offering: Specialty trehalose for cosmetics

Fuyang Biotechnology specializes in high-purity trehalose for skincare and functional foods. The company collaborates with research institutions to develop next-generation applications.

Innovation Highlights:

  • Patented skincare stabilization formulations

  • Expanding into Middle Eastern and European markets


5️⃣ 6. BASF SE

Headquarters: Ludwigshafen, Germany
Key Offering: Ultra-pure pharmaceutical trehalose

The chemical conglomerate BASF has positioned its trehalose offerings in high-value pharmaceutical and cosmetic applications, leveraging its global distribution network.

Innovation Highlights:

  • Proprietary active ingredient delivery systems

  • Carbon-neutral production initiatives

Download FREE Sample Report: Trehalose Market – View in Detailed Research Report


4️⃣ 7. Cargill, Incorporated

Headquarters: Minnesota, USA
Key Offering: Food-grade trehalose solutions

Cargill distributes trehalose through its global food ingredients network, particularly in North America and Europe. The company emphasizes clean-label and functional food applications.

Innovation Highlights:

  • Market positioning as natural shelf-life extender

  • Development of reduced-sugar formulations


3️⃣ 8. Merck KGaA

Headquarters: Darmstadt, Germany
Key Offering: GMP-certified trehalose

Merck specializes in pharmaceutical-grade trehalose for biologics stabilization and vaccine formulations. The company’s products meet stringent regulatory requirements worldwide.

Innovation Highlights:

  • GMP manufacturing facilities globally

  • Proprietary stabilization technologies


2️⃣ 9. Ashland Global Holdings Inc.

Headquarters: Delaware, USA
Key Offering: Cosmetic-grade trehalose

Ashland has become a preferred supplier to premium skincare brands, promoting trehalose’s skin-protective and moisturizing properties in anti-aging formulations.

Innovation Highlights:

  • Patented delivery systems for active ingredients

  • Customized skincare solutions


1️⃣ 10. DFE Pharma

Headquarters: Goch, Germany
Key Offering: Pharmaceutical excipient trehalose

DFE Pharma specializes in trehalose as a stabilizer for injectable medicines and biologics. The company provides technical support for drug formulation development.

Innovation Highlights:

  • Batch-to-batch consistency for regulatory compliance

  • Specialized particle size distributions

Get Full Report Here: Trehalose Market – View in Detailed Research Report


🌍 Market Outlook: Trehalose’s Cross-Industry Expansion

The trehalose market demonstrates robust potential, with food applications currently representing over 60% of demand, while pharmaceutical and cosmetic uses show the highest growth rates at 5.2% CAGR. Asia-Pacific dominates production and consumption, accounting for 75% of the global market.

📈 Key Market Developments:

  • Expanding use in mRNA vaccine stabilization post-pandemic

  • Growing adoption in premium anti-aging skincare formulations

  • Innovations in enzymatic production reducing costs by 20-25%

  • Increasing regulatory approvals for pharmaceutical applications

Get Full Report Here: Trehalose Market – View in Detailed Research Report

The companies featured above form the vanguard of trehalose innovation—not merely as suppliers, but as pioneers developing the next generation of applications that will drive market expansion through 2030 and beyond.