The Global Cosmetic Grade Squalene Market was valued at USD 76.50 Million in 2023 and is projected to reach USD 109.81 Million by 2030, growing at a Compound Annual Growth Rate (CAGR) of 5.3% during the forecast period (2024–2030). This expansion is driven by surging demand for natural skincare ingredients, heightened awareness of squalene’s anti-aging properties, and the premiumization of cosmetic products across global markets.

As clean beauty trends gain momentum worldwide, cosmetic-grade squalene has emerged as a gold-standard ingredient renowned for its superior moisturizing, antioxidant, and skin barrier-enhancing properties. This analysis highlights the Top 10 Companies in the Cosmetic Grade Squalene Industry—a diverse mix of biotechnology innovators, sustainable producers, and global ingredient suppliers revolutionizing skincare formulations.

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🔟 1. DKSH

Headquarters: Zurich, Switzerland
Key Offering: Pharmaceutical-grade vegetable squalene

DKSH operates as a premier distributor of high-performance cosmetic ingredients across 36 markets. Their cosmetic-grade squalene meets exacting purity standards required by luxury skincare brands, with full documentation of botanical sourcing and processing methods.

Quality Advantages:

• Multi-stage molecular distillation process
• Batch-to-batch consistency in composition
• GMP-certified manufacturing facilities

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Cosmetic Grade Squalene Market – View in Detailed Research Report

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9️⃣ 2. Clariant

Headquarters: Muttenz, Switzerland
Key Offering: Vegapure® plant-derived squalane

Clariant’s Care Chemicals division has pioneered sustainable alternatives to animal-derived squalene. Their Vegapure® line offers formulators a 100% plant-based solution with identical functional benefits to traditional squalene.

Technical Specifications:

• 99.8% purity threshold
• Halal and vegan certification
• Oxidation stability ≥24 months

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8️⃣ 3. Seadragon Marine Oils

Headquarters: Nelson, New Zealand
Key Offering: Deep-sea shark liver squalene

This specialist marine ingredients company maintains responsible sourcing partnerships with fisheries across the Southern Hemisphere. Their shark-derived squalene remains clinically validated for high-performance skincare applications.

Production Standards:

• IFOS 5-star certified marine oils
• Cold-processing techniques
• Heavy metal levels below 0.1ppm

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7️⃣ 4. Amyris

Headquarters: Emeryville, California, USA
Key Offering: Biosynthetic squalane (Neossance®)

Amyris leverages synthetic biology to produce sustainable squalane through proprietary fermentation technology. Their process converts plant sugars into molecularly identical alternatives to shark-derived squalene.

Biotech Breakthroughs:

• Patent-protected yeast strains
• Carbon-negative production
• Scalable fermentation capacity

Download FREE Sample Report:
Cosmetic Grade Squalene Market – View in Detailed Research Report

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6️⃣ 5. Maruha Nichiro

Headquarters: Tokyo, Japan
Key Offering: Ultra-pure shark origin squalene

As Japan’s largest marine products company, Maruha Nichiro combines generations of expertise with cutting-edge purification technologies. Their cosmetic grade squalene meets stringent Japanese quality standards for premium skincare applications.

Quality Parameters:

• Peroxide value <1.0 meq/kg
• Color value ≤100 (Lovibond)
• Moisture content ≤0.1%

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5️⃣ 6. Sophim

Headquarters: Peyruis, France
Key Offering: Phytosqualan® (olive-derived)

This French specialty chemical manufacturer produces Europe’s premier plant-based squalane. Sourced from Mediterranean olives, their Phytosqualan® offers exceptional stability and skin compatibility for luxury cosmetics.

Product Benefits:

• Neutral odor profile
• 98%+ carbon renewable index
• Non-comedogenic properties

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4️⃣ 7. Kishimoto Special Liver Oil

Headquarters: Tokyo, Japan
Key Offering: Medical-grade shark squalene

With over 80 years in lipid extraction, Kishimoto delivers ultra-refined squalene preferred by premium Asian skincare brands. Their advanced molecular distillation achieves pharmaceutical-grade purity levels.

Technical Features:

• Self-emulsifying properties
• Low viscosity formulation
• Fast skin absorption

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3️⃣ 8. Empresa Figueirense De Pesca

Headquarters: Figueira da Foz, Portugal
Key Offering: Ethically sourced marine squalene

This Portuguese marine biotech company combines traditional fishing heritage with modern sustainability practices. Their squalene production adheres to EU cosmetic regulations while maintaining full supply chain transparency.

Sustainability Credentials:

• IUCN-aligned sourcing policies
• Byproduct utilization programs
• Carbon footprint tracking

Download FREE Sample Report:
Cosmetic Grade Squalene Market – View in Detailed Research Report

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2️⃣ 9. Nucelis

Headquarters: La Jolla, California, USA
Key Offering: Precision-fermented squalene

Nucelis applies synthetic biology to create sustainable cosmetic ingredients through microbial fermentation. Their lab-grown squalene matches the molecular structure of natural variants while eliminating sourcing constraints.

Innovation Highlights:

• Proprietary microbial strains
• AI-optimized fermentation
• Custom carbon chain lengths

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1️⃣ 10. Arista Industries

Headquarters: Wilton, Connecticut, USA
Key Offering: Multi-origin squalene solutions

Arista provides formulation flexibility with both marine and plant-derived squalene options. Their global sourcing network and technical support team serve over 500 cosmetic brands worldwide.

Market Advantages:

• Dual supply chain redundancy
• Custom purity specifications
• Regulatory compliance expertise

Read Full Report:
Cosmetic Grade Squalene Market – View in Detailed Research Report

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🧖 Outlook: The Next Era of High-Performance Skincare Ingredients

The cosmetic squalene market stands at an inflection point, with biotechnology and sustainability reshaping ingredient sourcing. While shark-derived squalene still dominates certain premium segments, fermentation-derived alternatives are gaining share at a 32% annual growth rate as brands prioritize clean beauty commitments.

✨ Transformational Industry Trends:

• Accelerating adoption of bioengineered squalene alternatives
• Increasing incorporation in cosmeceutical and medical skincare
• Rising demand for multifunctional active ingredients
• Growing preference for clinically validated skincare components

Read Full Report:
Cosmetic Grade Squalene Market – View in Detailed Research Report

The companies featured above represent the vanguard of cosmetic ingredient innovation—delivering the bioactive compounds powering the next generation of performance skincare solutions.