Hesperidinase Market: Trends, Growth, and Forecast (2025-2032)

In Business Insights
March 10, 2025

The global hesperidinase market is on a steady trajectory of growth, driven by increasing demand in various industries such as food and beverages, pharmaceuticals, and cosmetics. With a market size of USD 22 million in 2023, it is projected to reach USD 27.96 million by 2032, exhibiting a compound annual growth rate (CAGR) of 2.70%.

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What is Hesperidinase?

Hesperidinase, an enzyme that catalyzes the hydrolysis of hesperidin to produce hesperetin, is a white to dark brown powder or liquid. This enzyme is soluble in water but insoluble in ethanol and is highly hygroscopic. Found predominantly in citrus fruits, hesperidinase plays a critical role in breaking down hesperidin, a flavonoid glycoside, which has notable health benefits including antioxidant, anti-inflammatory, and antimicrobial properties. Its applications extend beyond the food industry into the production of nutraceuticals and pharmaceuticals, where it is used for the production of bioactive compounds.

Hesperidinase Market Dynamics: Current Trends and Technological Advancements

The global hesperidinase market is witnessing significant growth due to several factors:

  1. Rising Health Consciousness: With increasing consumer awareness of health and wellness, there has been a surge in demand for natural and bioactive compounds found in citrus fruits, including hesperidin and its derivatives. The growing inclination towards plant-based supplements and functional foods has driven the demand for hesperidinase.
  2. Expansion of Nutraceuticals: Nutraceuticals, which combine the health benefits of food with the therapeutic effects of drugs, are gaining popularity. As a key enzyme in the production of flavonoids like hesperetin, hesperidinase is seeing increased use in the nutraceutical industry. These flavonoids, known for their cardiovascular and anti-inflammatory properties, are in high demand among health-conscious consumers.
  3. Technological Advancements in Enzyme Production: Advances in biotechnology have enhanced the production processes of hesperidinase, making it more efficient and cost-effective. The use of fermentation and enzyme immobilization technologies has expanded production capacity and lowered the cost of manufacturing, which is beneficial for widespread market adoption.
  4. Increasing Demand for Plant-Based Ingredients: The trend towards plant-based products in the food and beverage industry is another factor propelling the market. The clean-label movement, where consumers demand transparency and natural ingredients, has led to a higher demand for enzymes like hesperidinase in food products.

Recent Developments in the Hesperidinase Market

In recent years, there have been several noteworthy developments in the hesperidinase market:

  • Innovations in Enzyme Engineering: Biotechnology companies are focusing on enzyme optimization through genetic engineering and protein expression techniques. These innovations aim to improve the specificity, activity, and stability of hesperidinase, thereby broadening its range of applications.
  • Partnerships and Collaborations: Many market players have entered into strategic partnerships to advance their research on hesperidinase. Collaborations between research institutions and biotechnology firms are driving the development of innovative enzyme production methods and their integration into various industries.
  • Increase in Citrus Processing: As citrus processing becomes more advanced, the need for enzymes to extract bioactive compounds has increased. This has resulted in greater utilization of hesperidinase to enhance the yield and quality of citrus-derived products such as juices, extracts, and dietary supplements.
  • Regulatory Approvals and Certifications: Recent approvals from regulatory bodies, such as the Food and Drug Administration (FDA) and European Food Safety Authority (EFSA), have enabled market players to introduce hesperidinase-based products into new regions, enhancing global market accessibility.

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Future Growth Prospects and Market Forecast

The future of the hesperidinase market looks promising with a projected CAGR of 2.70% from 2025 to 2032. Several factors contribute to the optimistic outlook for this market:

  1. Expanding Applications in the Pharmaceutical Industry: With the growing focus on natural and sustainable alternatives in drug formulation, the pharmaceutical industry is expected to continue driving demand for hesperidinase. The enzyme’s role in the production of natural antioxidants and anti-inflammatory agents aligns with the increasing trend toward plant-based therapeutics.
  2. Emerging Markets: As the demand for functional foods, supplements, and natural healthcare products grows in developing regions like Asia-Pacific, the Middle East, and Latin America, hesperidinase is poised for expansion in these untapped markets.
  3. Sustainability and Green Chemistry: As sustainability becomes a more significant priority across industries, enzymes like hesperidinase, which are natural catalysts, are gaining traction. Their ability to facilitate environmentally friendly production processes aligns with the growing demand for green chemistry solutions in both food and pharmaceutical industries.
  4. Investment in Research and Development (R&D): Companies are increasingly investing in R&D to improve the enzymatic efficiency and scalability of hesperidinase production. This will ensure that the market can meet the growing demand from multiple industries, while also pushing the boundaries of what is possible with this enzyme.

FAQs :-

1. What is the size of the global Hesperidinase market in 2023?

The global Hesperidinase market was valued at USD 22 million in 2023.

2. What is the projected growth of the Hesperidinase market by 2032?

The Hesperidinase market is expected to reach USD 27.96 million by 2032, with a compound annual growth rate (CAGR) of 2.70% during the forecast period.

3. What factors are driving the growth of the Hesperidinase market?

The growth of the Hesperidinase market is primarily driven by the increasing demand for natural and plant-based enzymes in various industries, including food and beverages, pharmaceuticals, and cosmetics. Moreover, the rising trend toward health-conscious consumer behavior and the use of natural compounds for medical purposes contribute to this market’s expansion.

4. What is Hesperidinase used for?

Hesperidinase is an enzyme used to break down hesperidin, a flavonoid found in citrus fruits. It has applications in the food and beverage industry for improving the taste and flavor of products, as well as in the pharmaceutical and cosmetic industries for its antioxidant and anti-inflammatory properties.

5. What is the projected CAGR of the Hesperidinase market during the forecast period?

The global Hesperidinase market is projected to exhibit a CAGR of 2.70% from 2023 to 2032.

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/ Published posts: 372

Aditya is a dedicated researcher and writer with a profound interest in the world of chemicals and material science. As an author for the Chemical Research Insights blog, Aditya focuses on delivering in-depth analysis and updates on the latest developments in the chemical industry, from specialty chemicals and advanced materials to sustainability-driven innovations. With a strong academic background and hands-on experience in industrial chemistry, Aditya excels at breaking down intricate concepts into actionable insights. His articles are known for their clarity, precision, and relevance, making them a trusted resource for professionals, academics, and enthusiasts alike. Beyond writing, Aditya is an advocate for green chemistry and sustainable practices, often exploring topics that highlight the intersection of technology, environment, and industry growth. He is passionate about fostering awareness of innovative solutions that drive efficiency and environmental stewardship. Connect with Aditya on Chemical Research Insights for expert perspectives on the trends shaping the chemical and materials science industries.

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