The Global 10-Hydroxycamptothecin Market was valued at USD 7.9 Million in 2025 and is projected to reach USD 10.3 Million by 2034, growing at a Compound Annual Growth Rate (CAGR) of 3.7% during the forecast period. This steady growth is primarily driven by the rising global incidence of various cancers, increasing investment in oncology R&D, and the proven efficacy of camptothecin derivatives in targeted cancer therapies.

As the pharmaceutical industry intensifies its focus on developing more effective and less toxic chemotherapeutic agents, the spotlight falls on the specialized manufacturers producing this critical active pharmaceutical ingredient (API). In this analysis, we profile the Top 10 Companies in the 10-Hydroxycamptothecin Industry—a group of fine chemical and pharmaceutical specialists shaping the supply chain for innovative cancer treatments.

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🔟 1. TAIZHOU CREATING BIO-PHARM

Headquarters: Taizhou, Jiangsu, China
Key Offering: High-Purity 10-Hydroxycamptothecin API (>99.5%)

TAIZHOU CREATING BIO-PHARM is a leading global supplier of 10-Hydroxycamptothecin, specializing in the production of high-purity Active Pharmaceutical Ingredients (APIs) derived from natural plant extracts. The company leverages advanced extraction and purification technologies to serve pharmaceutical companies worldwide.

Research & Development Initiatives:

• Advanced chromatographic purification systems for enhanced purity

• Continuous process optimization for yield improvement

• Strict adherence to cGMP and international quality standards

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9️⃣ 2. Sichuan Xieli Pharmaceutical

Headquarters: Chengdu, Sichuan, China
Key Offering: 10-Hydroxycamptothecin for injectable formulations

Sichuan Xieli Pharmaceutical has established itself as a key manufacturer of anti-tumor APIs, with 10-Hydroxycamptothecin being one of its flagship products. The company supplies to both domestic and international markets, with a focus on meeting the stringent requirements for injectable drug formulations.

Research & Development Initiatives:

• Development of stable salt forms for improved solubility

• Investment in scalable synthesis pathways

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8️⃣ 3. Taizhou Hoyoo Chemical

Headquarters: Taizhou, Zhejiang, China
Key Offering: 10-Hydroxycamptothecin for research and pharmaceutical use

Taizhou Hoyoo Chemical specializes in the production of fine chemicals and pharmaceutical intermediates, including 10-Hydroxycamptothecin. The company serves a diverse client base, from academic research institutions to large pharmaceutical manufacturers.

Research & Development Initiatives:

• Optimization of synthetic routes for cost efficiency

• Expansion of GMP-compliant production capacity

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7️⃣ 4. Sichuan JingYu Chemical

Headquarters: Chengdu, Sichuan, China
Key Offering: High-purity 10-Hydroxycamptothecin and derivatives

Sichuan JingYu Chemical is a specialized manufacturer of naturally derived pharmaceutical compounds. The company has developed expertise in the complex extraction and purification processes required for camptothecin alkaloids, positioning it as a reliable supplier in the global market.

Research & Development Initiatives:

• Development of novel camptothecin analogs

• Quality control methods for batch-to-batch consistency

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6️⃣ 5. Chengdu Tianyuan

Headquarters: Chengdu, Sichuan, China
Key Offering: 10-Hydroxycamptothecin API and custom synthesis services

Chengdu Tianyuan operates as a contract manufacturer and supplier of pharmaceutical intermediates and APIs, with 10-Hydroxycamptothecin representing a significant part of its product portfolio. The company focuses on serving the needs of innovative drug developers.

Research & Development Initiatives:

• Custom synthesis services for derivative development

• Process development for regulatory compliance

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5️⃣ 6. Hangzhou Hyper Chemicals

Headquarters: Hangzhou, Zhejiang, China
Key Offering: Research-grade and pharmaceutical-grade 10-Hydroxycamptothecin

Hangzhou Hyper Chemicals has established a strong presence in the fine chemicals market, supplying high-quality 10-Hydroxycamptothecin to research laboratories and pharmaceutical companies. The company emphasizes technical support and customer collaboration.

Research & Development Initiatives:

• Development of analytical reference standards

• Stability studies for formulation support

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4️⃣ 7. Shaanxi Huike Botanical Development

Headquarters: Xi’an, Shaanxi, China
Key Offering: Plant-extracted 10-Hydroxycamptothecin

Shaanxi Huike Botanical Development specializes in the extraction of bioactive compounds from medicinal plants. The company utilizes sustainable sourcing practices for Camptotheca acuminata, the natural source of camptothecin precursors.

Research & Development Initiatives:

• Sustainable cultivation of source plants

• Green extraction technologies

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3️⃣ 8. Nanjing Dilger Medical Technology

Headquarters: Nanjing, Jiangsu, China
Key Offering: 10-Hydroxycamptothecin for clinical trial materials

Nanjing Dilger Medical Technology focuses on supplying high-purity compounds for pharmaceutical development and clinical research. The company’s 10-Hydroxycamptothecin meets the stringent requirements for Investigational New Drug (IND) applications.

Research & Development Initiatives:

• GMP manufacturing for clinical supply

• Impurity profiling and characterization

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2️⃣ 9. Wuhan Sunrise Technology

Headquarters: Wuhan, Hubei, China
Key Offering: 10-Hydroxycamptothecin and related analytical services

Wuhan Sunrise Technology provides both the compound and complementary analytical services to support drug development. The company’s expertise in quality control makes it a valuable partner for pharmaceutical companies requiring comprehensive documentation.

Research & Development Initiatives:

• Development of validated analytical methods

• Technical consulting for formulation development

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1️⃣ 10. Shanghai Jingsheng Pharmaceutical Technology

Headquarters: Shanghai, China
Key Offering: 10-Hydroxycamptothecin API and custom manufacturing

Shanghai Jingsheng Pharmaceutical Technology rounds out the top ten with its focus on pharmaceutical technology development and API manufacturing. The company serves global clients with a commitment to quality and regulatory compliance.

Research & Development Initiatives:

• Process validation for regulatory submissions

• Scale-up from laboratory to commercial production

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🧪 Outlook: The Future of 10-Hydroxycamptothecin Is More Targeted and Accessible

The 10-Hydroxycamptothecin market is evolving significantly. While the compound itself remains a vital chemotherapeutic agent, the industry is focusing on improved formulations, combination therapies, and expanding therapeutic applications beyond traditional oncology.

📈 Key Trends Shaping the Market:

• Development of liposomal and nanoparticle formulations for targeted delivery

• Increased use in combination therapies with other anticancer agents

• Expansion into new therapeutic areas beyond conventional cancers

• Growing emphasis on sustainable and scalable production methods

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10-Hydroxycamptothecin Market – View in Detailed Research Report

The companies profiled above are not only supplying a critical oncology ingredient—they’re enabling the next generation of cancer therapeutics through innovation and quality excellence.