The Global Sialic Acid Powder Market was valued at USD 185.7 Million in 2023 and is projected to reach USD 287.4 Million by 2030, growing at a Compound Annual Growth Rate (CAGR) of 6.4% during the forecast period (2024–2030). This significant growth is primarily driven by the rising demand for infant formula, increased focus on cognitive health supplements, and the expanding applications of sialic acid in biopharmaceuticals and advanced therapeutic development.

As the health and wellness industry pivots towards scientifically-backed, high-purity ingredients, the spotlight is on the key manufacturers who are driving innovation, ensuring supply chain integrity, and meeting stringent quality standards. In this blog, we profile the Top 10 Companies in the Sialic Acid Powder Industry—a mix of established biochemical giants and specialized biotechnology firms shaping the future of this critical ingredient.

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🔟 1. Oryza Oil & Fat Chemical Co., Ltd.

Headquarters: Ichihara, Chiba, Japan
Key Offering: High-Purity Sialic Acid Powder (N-Acetylneuraminic Acid)

Oryza is a leading global supplier of sialic acid, leveraging its expertise in carbohydrate chemistry and fermentation technology. The company specializes in producing high-purity N-Acetylneuraminic Acid (Neu5Ac) for the infant formula, pharmaceutical, and nutraceutical markets, with a strong focus on consistent quality and scalability.

Innovation and Quality Initiatives:

• Advanced enzymatic synthesis and purification processes
• Certifications for pharmaceutical and food-grade applications
• Strategic focus on expanding production capacity to meet growing global demand

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9️⃣ 2. Sanyo Fine Co., Ltd.

Headquarters: Tokyo, Japan
Key Offering: Sialic Acid (Neu5Ac) for Food and Pharma

Sanyo Fine is a prominent Japanese manufacturer with a robust portfolio of fine chemicals, including sialic acid. The company is known for its meticulous quality control and reliable supply chain, serving clients in the health food and pharmaceutical intermediates sectors across Asia and internationally.

Innovation and Quality Initiatives:

• Development of cost-effective production methodologies
• Strong R&D pipeline for novel sialic acid derivatives

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8️⃣ 3. Hubei Cabio Biotech Co., Ltd.

Headquarters: Wuhan, Hubei, China
Key Offering: Sialic Acid Powder, Biocatalysis Products

Cabio Biotech is a key Chinese player in the biotechnology sector, specializing in the research, development, and production of bioactive compounds. The company utilizes advanced biocatalysis and fermentation technologies to produce sialic acid, positioning itself as a major supplier for both domestic and international markets.

Innovation and Quality Initiatives:

• Investment in green and sustainable biomanufacturing processes
• Expansion of product portfolio to include sialylated oligosaccharides

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7️⃣ 4. Jiangsu Higrand Biotech Co., Ltd.

Headquarters: Taizhou, Jiangsu, China
Key Offering: Sialic Acid, Nucleotides, and other Biochemicals

Higrand Biotech is a rapidly growing biotechnology company with a diverse product range. Its sialic acid powder is widely used in infant nutrition and dietary supplements. The company has invested significantly in scaling up production to capitalize on the burgeoning demand from the Asia-Pacific region.

Innovation and Quality Initiatives:

• Vertical integration of raw material sourcing
• Focus on achieving high purity levels (>98%) for critical applications

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Sialic Acid Powder Market – View in Detailed Research Report

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6️⃣ 5. GlycoSphere (A part of Jennewein Biotechnologie GmbH)

Headquarters: Rheinbreitbach, Germany
Key Offering: Human Milk Oligosaccharides (HMOs) including Sialic Acid-containing compounds

While primarily known for HMOs, GlycoSphere (under the Jennewein Biotechnologie umbrella) is a critical innovator in the field of complex carbohydrates. The company’s expertise in enzymatic synthesis makes it a significant player for high-value sialic acid derivatives used in premium infant formula and clinical nutrition.

Innovation and Quality Initiatives:

• Pioneering research in the biofunctional benefits of sialylated compounds
• Strong IP portfolio around fermentation-based production

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5️⃣ 6. Zhejiang Nature Biotechnology Co., Ltd.

Headquarters: Hangzhou, Zhejiang, China
Key Offering: Plant Extracts, Amino Acids, Sialic Acid

Zhejiang Nature Biotechnology has established itself as a reliable supplier of natural ingredients. Its sialic acid powder is produced under strict quality management systems, catering to the nutraceutical and cosmetic industries with an emphasis on product safety and efficacy.

Innovation and Quality Initiatives:

• Implementation of ISO and HACCP standards
• Exploration of sialic acid applications in skincare and cosmeceuticals

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4️⃣ 7. Carbosynth Limited

Headquarters: Compton, Berkshire, United Kingdom
Key Offering: Research-grade Sialic Acid, Glycobiology Reagents

Carbosynth is a global supplier of carbohydrates, biochemicals, and research reagents. It serves the academic, diagnostic, and pharmaceutical R&D sectors with high-purity sialic acid products. The company is essential for early-stage research that fuels future commercial applications.

Innovation and Quality Initiatives:

• Extensive catalog of rare and complex sugars for research
• Custom synthesis services for specialized sialic acid derivatives

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3️⃣ 8. Delecta Biotech

Headquarters: Hunan, China
Key Offering: Sialic Acid Powder, Microbial Ingredients

Delecta Biotech focuses on the microbial fermentation production of high-value ingredients. The company’s sialic acid is recognized for its consistent quality and is increasingly used by manufacturers seeking non-animal-derived sources for their products, aligning with vegetarian and vegan trends.

Innovation and Quality Initiatives:

• Optimization of fermentation yields for economic production
• Commitment to sustainable and environmentally friendly manufacturing

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2️⃣ 9. HuaXiang Bio

Headquarters: Shandong, China
Key Offering: Food-grade and Pharmaceutical-grade Sialic Acid

HuaXiang Bio is a specialized manufacturer focusing on bioactive substances. The company has carved a niche by providing competitively priced sialic acid without compromising on purity, making it a popular choice for mass-market dietary supplements and functional foods.

Innovation and Quality Initiatives:

• Continuous process improvement to reduce production costs
• Building strong B2B relationships with global distributors

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1️⃣ 10. Inalco Pharmaceuticals

Headquarters: San Marcos, California, USA
Key Offering: Ultra-high Purity Sialic Acid for Pharmaceutical Applications

Inalco Pharmaceuticals specializes in complex carbohydrates for the pharmaceutical and diagnostic industries. While a more specialized player, it is crucial for providing the ultra-pure sialic acid required for glycobiology research, vaccine development, and novel therapeutic agents where exact structural integrity is paramount.

Innovation and Quality Initiatives:

• Focus on GMP-grade production for clinical applications
• Collaborations with academic institutions for groundbreaking research

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Sialic Acid Powder Market – View in Detailed Research Report

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🧬 Outlook: The Future of Sialic Acid Powder Is Driven by Science and Wellness

The sialic acid powder market is experiencing a transformative phase. While traditional applications in infant nutrition dominate current demand, the industry is investing heavily in R&D for new therapeutic and nutraceutical applications, advanced production technologies, and broader market penetration.

📈 Key Trends Shaping the Market:

• Rising consumer awareness of cognitive health and immunity boosting
• Increased incorporation of sialic acid in adult dietary supplements and medical foods
• Advancements in enzymatic and microbial fermentation technologies reducing production costs
• Growing research into sialic acid’s role in anti-aging skincare and neurology

Get Full Report Here:
Sialic Acid Powder Market – View in Detailed Research Report

The companies listed above are not only supplying a critical bioactive ingredient—they are enabling the next generation of health and wellness innovations.