The Global Sodium Acetylated Hyaluronate (AcHA) Market was valued at USD 42.5 Million in 2025 and is projected to reach USD 78.2 Million by 2034, growing at a Compound Annual Growth Rate (CAGR) of 7.8% during the forecast period (2024–2030). This robust growth is driven by the rising demand for advanced anti-aging skincare solutions, the increasing consumer preference for high-efficacy cosmetic ingredients, and the expansion of the premium cosmetics industry worldwide.

As the skincare sector evolves towards more sophisticated and scientifically-backed formulations, the focus shifts to the key ingredient manufacturers that are pioneering innovation in bioavailability and skin penetration. In this analysis, we profile the Top 10 Companies in the Sodium Acetylated Hyaluronate (AcHA) Market—a group of leading biotech firms and chemical suppliers that are defining the next generation of hyaluronic acid derivatives.

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🔟 1. Bloomage BioTechnology Corporation Limited

Headquarters: Jinan, Shandong, China
Key Offering: High-purity AcHA Powder, Custom Molecular Weight Grades

Bloomage BioTechnology is the world’s largest manufacturer of hyaluronic acid and its derivatives, holding a dominant position in the AcHA market. The company’s extensive R&D capabilities allow it to produce AcHA with superior moisture retention and skin penetration properties, catering to global cosmetic and pharmaceutical clients.

Innovation Initiatives:

• Patented enzymatic synthesis technology for AcHA production

• Strategic partnerships with L’Oréal, Estée Lauder, and other cosmetic giants

• Continuous investment in biotech research for novel HA derivatives

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9️⃣ 2. Shandong Focusfreda Biotech Co., Ltd.

Headquarters: Jinan, Shandong, China
Key Offering: Cosmetic-grade AcHA, Pharmaceutical-grade AcHA

Focusfreda Biotech specializes in the research, development, and production of hyaluronic acid and its acetylated form. The company has established itself as a key supplier to the Asian cosmetics market, with growing international exports.

Innovation Initiatives:

• Advanced purification processes ensuring 99%+ purity levels

• Focus on sustainable and green manufacturing practices

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8️⃣ 3. Shandong Weifang Tiansheng Group

Headquarters: Weifang, Shandong, China
Key Offering: AcHA raw materials, HA-based active ingredients

Tiansheng Group is a comprehensive enterprise engaged in the production of hyaluronic acid and its derivatives. The company has vertically integrated operations from raw material sourcing to finished product manufacturing.

Innovation Initiatives:

• Vertical integration strategy for cost-effective production

• Expansion into high-value cosmetic active ingredients

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7️⃣ 4. Topscience

Headquarters: Xi’an, Shaanxi, China
Key Offering: Ultra-pure AcHA, Customized HA derivatives

Topscience focuses on the development and production of high-quality hyaluronic acid derivatives for medical and cosmetic applications. The company is known for its technological expertise in modifying HA molecules for enhanced functionality.

Innovation Initiatives:

• Strong R&D focus on molecular modification technologies

• Collaborations with academic institutions for breakthrough research

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Sodium Acetylated Hyaluronate (AcHA) Market – View in Detailed Research Report

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6️⃣ 5. Contipro Group

Headquarters: Dolní Dobrouč, Czech Republic
Key Offering: AcHA under the Hyaluronan DV trademark

Contipro is a European leader in hyaluronic acid research and production, offering a wide range of HA derivatives including AcHA. The company combines biotechnology with nanotechnology to create advanced materials for cosmetics and pharmaceuticals.

Innovation Initiatives:

• Proprietary fermentation and purification technologies

• Focus on sustainable production from renewable resources

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5️⃣ 6. Givaudan Active Beauty

Headquarters: Vernier, Switzerland
Key Offering: AcHA-based active ingredients, Finished formulations

Givaudan, through its Active Beauty division, offers sophisticated AcHA ingredients as part of its comprehensive skincare actives portfolio. The company provides both raw materials and tailored solutions to cosmetic brands worldwide.

Innovation Initiatives:

• Integration of AcHA into multifunctional active complexes

• Strong focus on clinical efficacy and consumer-perceivable benefits

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4️⃣ 7. Evonik Industries AG

Headquarters: Essen, Germany
Key Offering: Specialty AcHA grades for premium cosmetics

Evonik’s Care Solutions business line includes high-performance ingredients for the personal care industry, with AcHA being part of their advanced skincare portfolio. The company leverages its chemical expertise to produce premium-grade materials.

Innovation Initiatives:

• Development of multifunctional skincare polymers

• Sustainability-driven product development approach

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3️⃣ 8. Shiseido Company, Limited

Headquarters: Tokyo, Japan
Key Offering: AcHA for in-house brands, Selective B2B supply

While primarily known as a cosmetic brand, Shiseido maintains significant R&D capabilities in ingredient development, including advanced hyaluronic acid derivatives like AcHA for its premium skincare lines.

Innovation Initiatives:

• Proprietary research on skin absorption and efficacy

• Vertical integration from ingredient development to finished products

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2️⃣ 9. CPN Spol. s r.o. (Contipro)

Headquarters: Dolní Dobrouč, Czech Republic
Key Offering: High-quality AcHA, Custom molecular weights

CPN, operating under the Contipro brand, is specialized in the development and production of hyaluronic acid and its derivatives. The company offers AcHA with specific molecular characteristics tailored to customer requirements.

Innovation Initiatives:

• Focus on pharmaceutical-grade purity standards

• Custom synthesis services for specialized applications

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1️⃣ 10. Fidelity Chemicals (Hyaluronic Acid Division)

Headquarters: Guangzhou, Guangdong, China
Key Offering: Cost-effective AcHA, Bulk supply options

Fidelity Chemicals has established itself as a reliable supplier of hyaluronic acid derivatives, including AcHA, to the global market. The company focuses on delivering quality products at competitive prices.

Innovation Initiatives:

• Process optimization for enhanced production efficiency

• Expansion into emerging markets with tailored product offerings

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Sodium Acetylated Hyaluronate (AcHA) Market – View in Detailed Research Report

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🌍 Outlook: The Future of Sodium Acetylated Hyaluronate Is Smarter Formulations and Broader Applications

The Sodium Acetylated Hyaluronate market is experiencing a significant transformation. While traditional hyaluronic acid continues to be widely used, the industry is increasingly adopting acetylated variants for their superior skin penetration and prolonged moisturizing effects.

📈 Key Trends Shaping the Market:

• Rising demand for anti-aging products with proven efficacy

• Growth in premium skincare segments across Asia-Pacific and North America

• Increasing investment in research for multifunctional cosmetic actives

• Expansion of AcHA applications into pharmaceutical and dermal fillers

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Sodium Acetylated Hyaluronate (AcHA) Market – View in Detailed Research Report

The companies profiled above are not only supplying critical ingredients to the global cosmetics industry—they’re driving the scientific advancement of skincare formulations.