The Global Medical Plasmin Market was valued at USD 287.5 Million in 2023 and is projected to reach USD 432.1 Million by 2030, growing at a Compound Annual Growth Rate (CAGR) of 6.2% during the forecast period (2024–2030). This robust growth is primarily driven by the rising prevalence of thrombotic disorders, increasing applications in wound care and ophthalmic surgeries, and expanding research and development activities in life sciences.

As the demand for advanced therapeutic enzymes surges, the medical plasmin market is attracting significant investment from leading biopharmaceutical and life sciences companies. These key players are not only manufacturing high-purity plasmin but also pioneering novel applications and production technologies. In this blog, we profile the Top 10 Companies in the Medical Plasmin Industry—a diverse group of innovators shaping the future of this critical enzyme market.

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Medical Plasmin Market – View in Detailed Research Report

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🔟 1. Kedrion (Prometic)

Headquarters: Castelvecchio Pascoli, Italy
Key Offering: High-Purity Plasmin for Therapeutic Use, Plasma-Derived Therapies

Kedrion, through its acquisition of Prometic’s plasma assets, is a major force in the plasma-derived therapeutics market. The company specializes in purifying proteins from human plasma, including plasmin, which is used in critical medical procedures to dissolve blood clots.

Research & Development Initiatives:

• Advanced plasmin purification technologies for enhanced efficacy and safety

• Clinical development of plasmin for intravitreal injection in eye diseases

• Focus on expanding indications for plasmin-based therapies

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9️⃣ 2. Thermo Fisher Scientific Inc.

Headquarters: Waltham, Massachusetts, USA
Key Offering: Research-Grade Plasmin, Biochemical Reagents, Assay Kits

Thermo Fisher Scientific is a global leader serving the life sciences industry. Its portfolio includes high-quality plasmin and related enzymes used extensively in biomedical research, drug discovery, and diagnostic assay development.

Research & Development Initiatives:

• Production of ultra-pure plasmin for sensitive research applications

• Integration of plasmin into comprehensive proteomics and cell culture systems

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8️⃣ 3. Merck KGaA

Headquarters: Darmstadt, Germany
Key Offering: Plasmin for Research, Process Solutions for Biomanufacturing

Merck KGaA provides essential products and services to the scientific community, including high-purity enzymes like plasmin. Its MilliporeSigma division is a key supplier of biochemicals that support academic research and biopharmaceutical production.

Research & Development Initiatives:

• Development of cGMP-grade plasmin for therapeutic manufacturing processes

• Investment in novel enzyme stabilization and delivery technologies

Download FREE Sample Report:
Medical Plasmin Market – View in Detailed Research Report

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7️⃣ 4. Genzyme Corporation (Sanofi)

Headquarters: Cambridge, Massachusetts, USA
Key Offering: Specialty Therapeutics, Enzyme Replacement Therapies

As a subsidiary of Sanofi, Genzyme is renowned for its expertise in developing enzyme-based treatments for rare diseases. While not a direct plasmin manufacturer, its deep knowledge of therapeutic enzymes and bioprocessing positions it as an influential player in the broader enzyme therapeutics space.

Research & Development Initiatives:

• Pioneering work in recombinant enzyme production techniques

• Exploration of novel enzyme applications in metabolic and genetic disorders

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6️⃣ 5. Promega Corporation

Headquarters: Madison, Wisconsin, USA
Key Offering: Molecular Biology Reagents, Proteases including Plasmin

Promega Corporation is a leading provider of innovative solutions for life sciences research. The company supplies high-quality plasmin primarily for use in laboratory settings, supporting studies in fibrinolysis, cell signaling, and protein biochemistry.

Research & Development Initiatives:

• Development of specialized plasmin formulations for specific research applications

• Creation of配套检测试剂盒 to measure plasmin activity

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5️⃣ 6. Asahi Kasei Corporation

Headquarters: Tokyo, Japan
Key Offering: Medical Devices, Bioprocessing Materials, Plasmin-related Products

Asahi Kasei is a diversified Japanese multinational with a significant presence in healthcare. Its medical segment engages in the development of technologies related to blood processing and purification, placing it within the plasmin ecosystem.

Research & Development Initiatives:

• R&D in advanced separation technologies for plasma protein purification

• Collaborations with academic institutions on novel therapeutic applications for fibrinolytic enzymes

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4️⃣ 7. Takeda Pharmaceutical Company Limited

Headquarters: Tokyo, Japan
Key Offering: Plasma-Derived Therapies, Hematology Products

Takeda is a global biopharmaceutical leader with a strong portfolio in plasma-derived therapies. Its expertise in fractionating plasma to produce vital proteins, such as immunoglobulins and clotting factors, underpins its strategic position in the plasmin supply chain.

Research & Development Initiatives:

• Continuous improvement of plasma fractionation yields and purity

• Investment in next-generation plasma purification platforms

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3️⃣ 8. Cytiva (Danaher)

Headquarters: Marlborough, Massachusetts, USA
Key Offering: Bioprocessing Equipment, Chromatography Resins, Consumables

Cytiva provides the essential tools and technologies that enable the production of biotherapeutics, including enzymes like plasmin. Its products are critical for the downstream purification processes used by plasmin manufacturers to achieve regulatory-grade purity.

Research & Development Initiatives:

• Innovation in chromatography media for efficient plasmin purification

• Development of single-use systems for flexible and scalable bioprocessing

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2️⃣ 9. Agilent Technologies, Inc.

Headquarters: Santa Clara, California, USA
Key Offering: Analytical Instruments, Bio-reagents, Solutions for QA/QC

Agilent Technologies is a key enabler in the life sciences and diagnostic markets. The company provides sophisticated analytical instruments and reagents used to characterize, quantify, and ensure the quality of plasmin products throughout the development and manufacturing lifecycle.

Research & Development Initiatives:

• Advancements in liquid chromatography and mass spectrometry for protein analysis

• Development of validated methods for plasmin potency and purity testing

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1️⃣ 10. Sun Pharmaceutical Industries Ltd.

Headquarters: Mumbai, India
Key Offering: Generic and Specialty Pharmaceuticals, Active Pharmaceutical Ingredients (APIs)

As one of the world’s largest specialty generic pharmaceutical companies, Sun Pharma has extensive manufacturing capabilities. Its expertise in producing complex APIs and biologics positions it as a potential significant manufacturer of therapeutic enzymes, including plasmin, for global markets.

Research & Development Initiatives:

• Investment in biopharmaceutical R&D and manufacturing infrastructure

• Focus on expanding its portfolio in niche therapeutic areas, including hematology

Read Full Report:
Medical Plasmin Market – View in Detailed Research Report

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🧬 Outlook: The Future of Medical Plasmin Is Precision and Innovation

The medical plasmin market is undergoing a significant transformation. While its traditional use in research and specific therapeutic areas remains strong, the industry is actively exploring new frontiers in precision medicine and advanced therapies.

📈 Key Trends Shaping the Market:

• Expansion into novel therapeutic areas like ophthalmology for vitreoretinal surgery

• Development of recombinant plasmin technologies to reduce reliance on human plasma

• Increasing regulatory scrutiny and emphasis on high-purity, well-characterized enzyme products

• Strategic collaborations between biotech innovators and large pharmaceutical companies to accelerate product development

Read Full Report:
Medical Plasmin Market – View in Detailed Research Report

The companies listed above are not only supplying a critical enzyme—they are actively driving innovation in life sciences and therapeutic development.