The Global Water-soluble Vitamin D3 Market was valued at USD 145.8 Million in 2023 and is projected to reach USD 215.3 Million by 2030, growing at a Compound Annual Growth Rate (CAGR) of 5.7% during the forecast period (2024–2030). This robust growth is primarily driven by rising global awareness of vitamin D deficiency, increasing fortification of food and beverages, and the superior bioavailability of water-soluble D3 formulations compared to traditional oil-based versions.

As the nutraceutical and pharmaceutical industries pivot towards more effective and accessible nutrient delivery systems, the focus intensifies on the key manufacturers who are pioneering advanced formulation technologies. In this blog, we profile the Top 10 Companies in the Water-soluble Vitamin D3 Market—a blend of chemical giants, specialized ingredient suppliers, and innovators shaping the future of nutritional science.

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Water-soluble Vitamin D3 Market – View in Detailed Research Report

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🔟 1. BASF SE

Headquarters: Ludwigshafen, Germany
Key Offering: Vitamin D3 Powder (Water-soluble), DEKABON® D3

BASF is a global leader in the chemical industry and a major producer of vitamins and nutritional ingredients. Its water-soluble Vitamin D3 products are designed for enhanced stability and bioavailability in a wide range of applications, from dietary supplements to fortified dairy and beverages.

Innovation & Sustainability Initiatives:

• Investment in advanced microencapsulation technologies for superior solubility
• Commitment to sustainable production processes and reducing environmental footprint
• Global supply chain ensuring consistent quality and availability

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9️⃣ 2. DSM-Firmenich

Headquarters: Kaiseraugst, Switzerland
Key Offering: Quali®-D Water-Soluble Vitamin D3

Following the merger of DSM and Firmenich, the company has strengthened its position as a powerhouse in health, nutrition, and beauty. DSM’s Quali®-D is a renowned brand, and its water-soluble variants are trusted by manufacturers worldwide for their high purity and performance in clear liquid applications.

Innovation & Sustainability Initiatives:

• Focus on science-backed solutions for public health challenges like vitamin D deficiency
• Development of novel delivery formats for improved consumer compliance
• Ambitious sustainability targets including carbon-neutral operations

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8️⃣ 3. Zhejiang Garden Biochemical High-Tech Co., Ltd.

Headquarters: Tongxiang, Zhejiang, China
Key Offering: Water-soluble Vitamin D3 Powder, Crystalline Vitamin D3

As one of the world’s largest manufacturers of Vitamin D3, Zhejiang Garden Biochemical has a significant market share. The company has heavily invested in R&D to produce high-quality water-soluble forms, catering to the growing demand in the Asian and global markets for fortified foods and supplements.

Innovation & Sustainability Initiatives:

• Vertically integrated production from cholesterol to finished Vitamin D3
• Expansion of production capacity to meet rising global demand
• Focus on cost-effective manufacturing while maintaining high-quality standards

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7️⃣ 4. Zhejiang NHU Co., Ltd.

Headquarters: Xinchang County, Zhejiang, China
Key Offering: NHU Vitamin D3 (Water-soluble grades)

NHU is a leading global supplier of fine chemicals and nutritional ingredients. The company’s Vitamin D3 portfolio includes water-soluble formulations that are used extensively in the pharmaceutical and food industries, supported by its strong manufacturing capabilities and extensive distribution network.

Innovation & Sustainability Initiatives:

• Continuous process optimization for improved yield and purity
• Strategic partnerships with global distributors and end-users
• Investment in green chemistry principles for sustainable production

Download FREE Sample Report:
Water-soluble Vitamin D3 Market – View in Detailed Research Report

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6️⃣ 5. BASF Petronas Chemicals Sdn. Bhd. (BPC)

Headquarters: Kuantan, Pahang, Malaysia
Key Offering: Vitamin D3 precursors and intermediates

This joint venture between BASF and Petronas plays a crucial role in the vitamin D3 supply chain. While its direct offerings are often precursors, its production capacity is vital for the global market’s stability, influencing the availability and pricing of finished water-soluble Vitamin D3.

Innovation & Sustainability Initiatives:

• State-of-the-art production facility with a focus on operational excellence
• Integration into BASF’s global vitamin manufacturing network
• Commitment to responsible care and sustainable practices

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5️⃣ 6. Taizhou Hisound Pharmaceutical Co., Ltd.

Headquarters: Taizhou, Jiangsu, China
Key Offering: Pharmaceutical-grade Water-soluble Vitamin D3

Hisound Pharmaceutical specializes in the research, development, and production of pharmaceutical raw materials, including high-purity Vitamin D3. The company has developed advanced water-soluble formulations specifically designed for pharmaceutical applications, such as injectables and oral solutions.

Innovation & Sustainability Initiatives:

• Strong focus on R&D for pharmaceutical applications
• Compliance with stringent international quality standards (GMP, USP, EP)
• Expansion into innovative dosage forms for improved therapeutic outcomes

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4️⃣ 7. Fermenta Biotech Ltd. (Formerly known as Aurore Life Science)

Headquarters: Mumbai, Maharashtra, India
Key Offering: D-MAX™ Water Soluble Vitamin D3

Fermenta Biotech is a significant player in the Vitamin D space, with a dedicated focus on fermentation technology. Its D-MAX™ brand offers a highly bioavailable, cold-water-soluble form of Vitamin D3 that is ideal for fortifying a wide array of products without altering taste or appearance.

Innovation & Sustainability Initiatives:

• Proprietary fermentation-based manufacturing process
• Focus on developing customized solutions for specific customer needs
• Investment in biotechnology for sustainable ingredient production

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3️⃣ 8. Kingdomway Nutrition Inc.

Headquarters: Ontario, California, USA (Subsidiary of Zhejiang Kingdomway)

Key Offering: Water-soluble Vitamin D3 for the North American market

Kingdomway Nutrition serves as a key link between Chinese manufacturing prowess and the demanding North American market. The company provides high-quality, competitively priced water-soluble Vitamin D3 to supplement and functional food manufacturers across the continent.

Innovation & Sustainability Initiatives:

• Strategic logistics and distribution network in North America
• Focus on regulatory compliance and quality assurance for the US and Canadian markets
• Providing technical support and formulation expertise to customers

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2️⃣ 9. Powelbone (Zhejiang Powelbone Pharmaceutical Co., Ltd.)

Headquarters: Quzhou, Zhejiang, China
Key Offering: Vitamin D3 API and Water-soluble formulations

Powelbone is a specialized manufacturer of steroidal APIs and Vitamin D3. The company has developed expertise in creating water-soluble forms that meet the specific requirements of the pharmaceutical and high-end nutraceutical industries.

Innovation & Sustainability Initiatives:

• Specialization in sterol chemistry and Vitamin D3 synthesis
• Focus on high-purity products for sensitive applications
• Ongoing R&D to improve solubility and stability characteristics

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1️⃣ 10. Siji Biology (Hangzhou Siji Biology Co., Ltd.)

Headquarters: Hangzhou, Zhejiang, China
Key Offering: Water-soluble Vitamin D3 for animal nutrition and human applications

Siji Biology is an emerging player focused on the research and production of biological products, including water-soluble vitamins. The company caters to both the animal feed and human nutrition sectors, offering formulations that improve the absorption of Vitamin D3 in various mediums.

Innovation & Sustainability Initiatives:

• Diversified product portfolio targeting both human and animal health
• Investment in application research to demonstrate efficacy
• Growing presence in international markets through strategic exports

Read Full Report:
Water-soluble Vitamin D3 Market – View in Detailed Research Report

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🌍 Outlook: The Future of Water-soluble Vitamin D3 Is Bright and Bioavailable

The Water-soluble Vitamin D3 market is experiencing a fundamental transformation. While traditional oil-based forms still hold a significant market share, the industry is rapidly adopting advanced solubilization technologies like microencapsulation, nanoemulsions, and cyclodextrin complexes to overcome the inherent challenges of fat-soluble vitamins.

📈 Key Trends Shaping the Market:

• Rising prevalence of vitamin D deficiency globally, driving preventive healthcare
• Increasing fortification of beverages, dairy alternatives, and powdered drinks
• Growing consumer preference for clean-label and highly bioavailable supplements
• Technological advancements in delivery systems enhancing stability and efficacy

Read Full Report:
Water-soluble Vitamin D3 Market – View in Detailed Research Report

The companies listed above are not only supplying a critical nutrient—they are enabling a healthier future through scientific innovation and global reach.