The Global Chlorhexidine Gluconate Market was valued at USD 742.8 Million in 2024 and is projected to reach USD 1.1 Billion by 2029, growing at a Compound Annual Growth Rate (CAGR) of 6.8% during the forecast period (2024–2029). This robust growth is being driven by increasing awareness of infection prevention and control (IPC), rising demand for advanced oral care products, and the expanding applications of chlorhexidine gluconate in both healthcare and consumer goods sectors.

As global health priorities continue to emphasize hygiene and antimicrobial efficacy, the spotlight is on the key manufacturers and suppliers who are driving innovation, quality, and accessibility. In this blog, we profile the Top 10 Companies in the Chlorhexidine Gluconate Industry—a mix of healthcare giants, chemical specialists, and consumer product leaders shaping the future of antiseptic solutions.

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🔟 1. 3M Company

Headquarters: Maplewood, Minnesota, USA
Key Offering: 3M™ SoluPrep™ Chlorhexidine Gluconate (CHG) Solution, skin antiseptics

3M is a global leader in healthcare and infection prevention, offering a comprehensive portfolio of CHG-based products. Their solutions are widely used for patient pre-surgical skin preparation to reduce the risk of surgical site infections (SSIs) in hospitals worldwide.

Innovation & Market Focus:

• Advanced formulation for persistent antimicrobial activity

• Focus on healthcare-associated infection (HAI) reduction

• Strong presence in North American and European hospital markets

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9️⃣ 2. Ecolab Inc.

Headquarters: St. Paul, Minnesota, USA
Key Offering: Surgical and healthcare antiseptics, Skin & Wound Care solutions

Ecolab provides critical infection prevention solutions to healthcare facilities globally. Their chlorhexidine gluconate products are integral to their comprehensive hygiene and sanitation programs for hospitals, clinics, and long-term care facilities.

Innovation & Market Focus:

• Integrated solutions for surgical site preparation

• Emphasis on sustainability and reduced environmental impact

• Global distribution network serving over 170 countries

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8️⃣ 3. BASF SE

Headquarters: Ludwigshafen, Germany
Key Offering: Chlorhexidine Gluconate API (Active Pharmaceutical Ingredient)

BASF is a leading chemical company and a major supplier of high-quality chlorhexidine gluconate as a raw material. They supply pharmaceutical and personal care manufacturers globally, ensuring strict quality control and regulatory compliance.

Innovation & Market Focus:

• Production of pharmaceutical-grade CHG

• Strong foothold in the European and Asian API markets

• Investment in sustainable chemical production processes

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7️⃣ 4. Johnson & Johnson (J&J)

Headquarters: New Brunswick, New Jersey, USA
Key Offering: LISTERINE® mouthwash with CHG, surgical care products

Through its Consumer Health division (Kenvue), Johnson & Johnson is a dominant player in the over-the-counter oral care market. Their LISTERINE brand, which includes formulations with chlorhexidine gluconate, is one of the world’s most recognized mouthwashes.

Innovation & Market Focus:

• Brand leadership in consumer oral antiseptics

• Extensive consumer marketing and education campaigns

• Broad retail distribution across pharmacies and supermarkets

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Chlorohexidine Gluconate Global Market – View in Detailed Research Report

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6️⃣ 5. GlaxoSmithKline plc (GSK)

Headquarters: London, United Kingdom
Key Offering: Corsodyl® mouthwash & gel, PanOptic™ CHG products

GSK’s consumer healthcare division markets Corsodyl, a leading CHG-based mouthwash brand in Europe and other markets, specifically indicated for treating and preventing gingivitis. Their products are backed by extensive clinical research.

Innovation & Market Focus:

• Specialization in evidence-based oral therapeutic products

• Strong focus on gum health and periodontal disease management

• Strategic partnerships with dental professionals

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5️⃣ 6. Xttrium Laboratories

Headquarters: Chicago, Illinois, USA
Key Offering: Chlorhexidine Gluconate solutions for compounding pharmacies

Xttrium Laboratories specializes in supplying high-quality active ingredients to the compounding pharmacy industry. They are a key supplier of chlorhexidine gluconate for customized medication preparations in hospitals and independent pharmacies.

Innovation & Market Focus:

• CGMP-compliant manufacturing for pharmacy compounding

• Specialization in niche and custom formulations

• Direct support for personalized patient care solutions

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4️⃣ 7. ABC Compounding Company

Headquarters: Atlanta, Georgia, USA
Key Offering: Custom-compounded CHG formulations

ABC Compounding is a prominent US-based compounding pharmacy that develops and supplies tailored chlorhexidine gluconate preparations. They serve specific patient needs that cannot be met by mass-produced, commercially available products.

Innovation & Market Focus:

• Patient-specific CHG formulations (e.g., different concentrations, allergen-free bases)

• Strong regional presence in the Southeastern United States

• Focus on dermatological and pre-surgical applications

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3️⃣ 8. B. Braun SE

Headquarters: Melsungen, Germany
Key Offering: Disinfectants and antiseptics for hospital use

B. Braun is a leading global healthcare company with a strong portfolio of infection control products. Their chlorhexidine gluconate-based skin antiseptics are essential components of their “Sharing Expertise” healthcare solutions.

Innovation & Market Focus:

• Integrated catheter care bundles incorporating CHG

• Leadership in hospital procedure trays and kits

• Global manufacturing and distribution capabilities

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2️⃣ 9. Henkel AG & Co. KGaA

Headquarters: Düsseldorf, Germany
Key Offering: CHG in consumer detergents and hygiene products

While primarily known for consumer brands, Henkel utilizes chlorhexidine gluconate in specific professional and consumer hygiene product lines. Their industrial applications include disinfectants and preservatives where broad-spectrum antimicrobial activity is required.

Innovation & Market Focus:

• Application of CHG in laundry and surface disinfectants

• Research into synergistic effects with other antimicrobials

• Expansion in emerging markets with growing hygiene awareness

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1️⃣ 10. Medical Chemical Corporation

Headquarters: Torrance, California, USA
Key Offering: Laboratory and diagnostic-grade CHG solutions

Medical Chemical Corporation specializes in reagents and chemicals for the diagnostic and laboratory markets. They supply chlorhexidine gluconate for use in medical, research, and biotechnology applications, ensuring high purity and consistency.

Innovation & Market Focus:

• Supply of CHG for in-vitro diagnostics and laboratory procedures

• Quality control for research and development applications

• Serving niche B2B markets with specialized chemical needs

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Chlorohexidine Gluconate Global Market – View in Detailed Research Report

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🌍 Outlook: The Future of Chlorhexidine Gluconate Is Integrated and Preventive

The chlorhexidine gluconate market is undergoing a significant transformation. While traditional applications in oral care and surgical scrubs remain strong, the industry is increasingly focused on innovative delivery systems, combination products, and expanding into new therapeutic areas.

📈 Key Trends Shaping the Market:

• Rising use of CHG-impregnated medical devices (e.g., central line dressings)

• Development of sustained-release CHG formulations for extended protection

• Growing demand in emerging economies for affordable antiseptic solutions

• Increased regulatory scrutiny and emphasis on product safety and efficacy data

Get Full Report Here:
Chlorohexidine Gluconate Global Market – View in Detailed Research Report

The companies listed above are not only supplying essential antiseptic products—they’re pioneering the next generation of infection control strategies that are vital for global public health.