The Global Pharmaceutical Grade Monoammonium Glycyrrhizinate Market was valued at US$ 187.6 Million in 2023 and is projected to reach US$ 265.3 Million by 2030, growing at a Compound Annual Growth Rate (CAGR) of 5.2% during the forecast period (2024–2030). This robust growth trajectory is primarily fueled by the escalating demand for natural sweeteners and anti-inflammatory agents in pharmaceutical formulations, alongside increasing regulatory approvals for glycyrrhizin-based drugs across major healthcare markets.

As the pharmaceutical industry intensifies its focus on natural and safe active ingredients, the spotlight falls on the key manufacturers who are pioneering the production of high-purity Monoammonium Glycyrrhizinate (MAG). Derived from licorice root, MAG is prized for its sweetening properties – approximately 50 times sweeter than sucrose – and its therapeutic benefits, including anti-viral, anti-inflammatory, and hepatoprotective effects. In this blog, we profile the Top 10 Companies in the Pharmaceutical Grade Monoammonium Glycyrrhizinate Industry – a blend of established chemical giants and specialized botanical extract suppliers shaping the future of pharmaceutical excipients and APIs.

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🔟 1. VITAL-CHEM Zhuhai Co., Ltd.

Headquarters: Zhuhai, Guangdong, China
Key Offering: High-Purity MAG (≥99%), Customized Glycyrrhizinate Derivatives

VITAL-CHEM Zhuhai is a leading global supplier of specialty ingredients, with a strong portfolio in pharmaceutical-grade botanical extracts. The company specializes in the production of high-purity Monoammonium Glycyrrhizinate, adhering to strict cGMP and ISO standards. Their MAG is widely used in cough syrups, lozenges, and injectable formulations requiring a natural sweetener with enhanced bioavailability.

Key Strategic Initiatives:

• Investment in advanced purification technologies for ≥99.5% purity MAG

• Strategic partnerships with global pharmaceutical contract manufacturers

• Expansion of R&D capabilities for novel glycyrrhizin-based drug delivery systems

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9️⃣ 2. Sabinsa Corporation

Headquarters: East Windsor, New Jersey, USA
Key Offering: Saberry® (Standardized Licorice Extracts), Pharmaceutical Grade MAG

Sabinsa is a renowned name in the nutraceutical and pharmaceutical ingredient space, with a deep-rooted expertise in botanicals. The company offers pharmaceutical-grade Monoammonium Glycyrrhizinate as part of its extensive licorice extract portfolio. Sabinsa’s commitment to science-backed ingredients is evidenced by its robust clinical research and patent portfolio surrounding glycyrrhizin’s applications.

Key Strategic Initiatives:

• Focus on Kosher, Halal, and GMP-certified production facilities

• Ongoing research into the synergistic effects of MAG with other bioactive compounds

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8️⃣ 3. Alchem International Pvt. Ltd.

Headquarters: New Delhi, India
Key Offering: Alchem MAG (Pharmaceutical Grade), Licorice Root Extracts

Alchem International has established itself as a major player in the plant-derived pharmaceutical ingredients market. With vertically integrated operations from raw material sourcing to final product manufacturing, the company ensures consistent quality and supply chain security for its Pharmaceutical Grade Monoammonium Glycyrrhizinate. Their products cater to a diverse clientele in the generics and branded pharmaceuticals sectors.

Key Strategic Initiatives:

• Backward integration with licorice root cultivators for sustainable sourcing

• Capacity expansion projects to meet growing North American and European demand

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7️⃣ 4. Shaanxi Fujie Pharmaceutical Co., Ltd.

Headquarters: Xi’an, Shaanxi, China
Key Offering: MAG for Injections, Tablet-Grade MAG

As a specialist in plant-extracted pharmaceutical ingredients, Shaanxi Fujie Pharmaceutical has a significant market share in the Asian MAG sector. The company’s strength lies in its ability to produce MAG suitable for various dosage forms, including stringent injectable-grade quality. Their manufacturing processes are designed to minimize glycyrrhetic acid content, a key impurity of concern.

Key Strategic Initiatives:

• Specialization in high-margin, application-specific MAG grades

• Active pursuit of regulatory approvals from the US FDA and European EMA

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Pharmaceutical Grade Monoammonium Glycyrrhizinate Market – View in Detailed Research Report

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6️⃣ 5. MAFCO Worldwide LLC (A McCormick & Company Subsidiary)

Headquarters: Camden, New Jersey, USA
Key Offering: Magnasweet® Flavors, Pharmaceutical Grade Licorice Extracts

MAFCO Worldwide is a globally recognized leader in licorice products, with a history spanning over a century. While widely known for its Magnasweet® flavor enhancers, the company is a critical supplier of the foundational licorice extracts used to produce Pharmaceutical Grade Monoammonium Glycyrrhizinate. Its extensive global sourcing network for Glycyrrhiza glabra root provides a significant competitive advantage.

Key Strategic Initiatives:

• Leveraging parent company McCormick’s global distribution network

• Focus on sustainable and ethical sourcing practices certified by third-party bodies

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5️⃣ 6. Alps Pharmaceutical Ind. Co., Ltd.

Headquarters: Gifu, Japan
Key Offering: Japanese Pharmacopoeia (JP) Grade MAG, High-Purity Glycyrrhizin

Alps Pharmaceutical is a key Asian manufacturer with a strong focus on quality and compliance with stringent pharmacopoeial standards, particularly the Japanese Pharmacopoeia (JP). The company’s Pharmaceutical Grade MAG is renowned for its high purity levels and consistency, making it a preferred choice for pharmaceutical companies targeting the exacting Japanese and Southeast Asian markets.

Key Strategic Initiatives:

• R&D focused on enhancing the solubility and stability of MAG in formulations

• Strategic exports to markets with high regulatory standards

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4️⃣ 7. BGG World (Beijing Gingko Group)

Headquarters: Beijing, China
Key Offering: BGG Monoammonium Glycyrrhizinate, ASTALIFT® Active Ingredients

BGG World is a leading supplier of botanical extracts for the cosmetic, nutraceutical, and pharmaceutical industries. The company’s pharmaceutical division produces high-quality Monoammonium Glycyrrhizinate, supported by its strong IP portfolio and scientific expertise. BGG’s vertical integration allows for tight control over the entire production process, from raw material selection to final purification.

Key Strategic Initiatives:

• Extensive investment in clinical research to validate MAG’s efficacy

• Development of proprietary extraction and purification technologies

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3️⃣ 8. Qingdao Taitong Pharmaceutical Co., Ltd.

Headquarters: Qingdao, Shandong, China
Key Offering: MAG for Syrups and Lozenges, Custom Purity Grades

Qingdao Taitong Pharmaceutical is a specialized manufacturer of pharmaceutical intermediates and active ingredients, with a significant output of Monoammonium Glycyrrhizinate. The company has built a reputation for reliability and cost-effectiveness, serving both domestic Chinese pharmaceutical companies and international clients. Their product range includes MAG tailored for specific applications like throat lozenges and pediatric syrups.

Key Strategic Initiatives:

• Cost-competitive manufacturing leveraging local licorice root supply

• Focus on expanding market presence in emerging economies

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2️⃣ 9. Jiangsu Tiansheng Pharmaceutical Co., Ltd.

Headquarters: Nanjing, Jiangsu, China
Key Offering: TSP MAG, Pharmaceutical Excipients

Jiangsu Tiansheng Pharmaceutical is a well-established API manufacturer in China, with a diversified product portfolio that includes Pharmaceutical Grade Monoammonium Glycyrrhizinate. The company’s strength lies in its modern manufacturing facilities and rigorous quality control systems that meet international standards. They are a key supplier to the growing domestic pharmaceutical market and export-oriented contract manufacturing organizations (CMOs).

Key Strategic Initiatives:

• Modernization of production lines to improve yield and reduce environmental impact

• Building long-term supply agreements with multinational pharmaceutical corporations

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1️⃣ 10. Shaanxi Jintai Biological Engineering Co., Ltd.

Headquarters: Xi’an, Shaanxi, China
Key Offering: Jintai MAG, Botanical Active Ingredients

Completing the top ten is Shaanxi Jintai Biological Engineering, a company focused on the research, development, and production of natural biological products. Their Pharmaceutical Grade Monoammonium Glycyrrhizinate is produced using proprietary bio-engineering techniques that enhance purity and reduce residual solvents. The company is actively exploring new applications for MAG in functional foods and advanced therapeutic systems.

Key Strategic Initiatives:

• Investment in green chemistry principles for sustainable manufacturing

• Exploration of MAG’s potential in novel drug delivery systems like nanoparticles

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Pharmaceutical Grade Monoammonium Glycyrrhizinate Market – View in Detailed Research Report

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🌍 Outlook: The Future of Pharmaceutical Grade MAG is Driven by Innovation and Regulation

The Pharmaceutical Grade Monoammonium Glycyrrhizinate market is undergoing a significant transformation. While demand from traditional applications like cough syrups remains strong, the industry is investing heavily in novel therapeutic applications, advanced purification technologies, and sustainable sourcing practices.

📈 Key Trends Shaping the Market:

• Expansion into New Therapeutic Areas: Growing research into MAG’s efficacy in treating liver disorders, dermatological conditions, and as an adjuvant in antiviral therapies is opening new revenue streams.

• Stringent Regulatory Scrutiny: Regulatory bodies like the FDA and EMA are imposing stricter limits on glycyrrhetic acid content, pushing manufacturers toward higher purity standards and more sophisticated analytical testing.

• Sustainability and Traceability: Increasing consumer and regulatory pressure for ethically sourced, sustainably harvested licorice root is compelling companies to invest in traceable supply chains and agricultural best practices.

• Synergy with Nutraceuticals: The blurring lines between pharmaceuticals and nutraceuticals are creating opportunities for MAG in dietary supplements targeting wellness and preventive health.

Get Full Report Here:
Pharmaceutical Grade Monoammonium Glycyrrhizinate Market – View in Detailed Research Report

The companies listed above are not only supplying a critical pharmaceutical ingredient—they are at the forefront of innovating and securing the sustainable future of plant-derived medicines.