The Global Liquiritigenin Market was valued at US$ 12.8 Million in 2023 and is projected to reach US$ 18.5 Million by 2030, growing at a Compound Annual Growth Rate (CAGR) of 5.4% during the forecast period (2024–2030). This expansion is driven by the rising consumer demand for natural therapeutic ingredients, increased research into flavonoid-based pharmaceuticals, and the growing application of liquiritigenin in the food and agriculture sectors.

As the health and wellness industry increasingly favors plant-derived, bioactive compounds, the focus shifts to the key manufacturers and suppliers who are ensuring the purity, availability, and innovation of this valuable flavonoid. In this blog, we profile the Top 10 Companies in the Liquiritigenin Industry—specialty chemical firms, biotechnology leaders, and research-focused suppliers shaping the future of natural product sourcing.

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🔟 1. Tocris Bioscience (Bio-Techne)

Headquarters: Minneapolis, Minnesota, USA
Key Offering: High-Purity Liquiritigenin (≥98%, ≥99%), Research-Use Only (RUO)

Tocris Bioscience, a Bio-Techne brand, is a leading global supplier of high-performance life science reagents, including premium-grade liquiritigenin. The company caters primarily to academic, pharmaceutical, and biotechnology research institutions, providing compounds of verified purity and biological activity for drug discovery and mechanistic studies.

Research & Development Focus:

• Supply of high-purity standards for pharmacological research

• Support for studies on ERβ (Estrogen Receptor Beta) activation and anti-inflammatory pathways

• Global distribution network ensuring reliable access for the scientific community

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9️⃣ 2. ChemFaces

Headquarters: Wuhan, Hubei, China
Key Offering: Liquiritigenin (98%-99% Purity), Natural Product Extracts

ChemFaces specializes in the isolation and synthesis of reference standards and natural products for research and development. The company is a key supplier of liquiritigenin, sourced from Glycyrrhiza species (licorice root), and serves a global clientele in the pharmaceutical and cosmetic industries.

Research & Development Focus:

• Development of analytical standards for quality control

• Extraction and purification technologies for plant-derived flavonoids

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8️⃣ 3. Merck KGaA

Headquarters: Darmstadt, Germany
Key Offering: Liquiritigenin (Analytical Standard, Research Grade)

Merck, a global science and technology leader, offers liquiritigenin as part of its extensive portfolio of life science chemicals and bioactives. Its products are integral to high-throughput screening, assay development, and academic research, backed by stringent quality assurance protocols.

Research & Development Focus:

• Integration into drug discovery and development workflows

• Commitment to sustainable and traceable sourcing of natural products

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7️⃣ 4. Santa Cruz Biotechnology, Inc.

Headquarters: Dallas, Texas, USA
Key Offering: Liquiritigenin (sc-202642), Antibodies, Biochemicals

Santa Cruz Biotechnology is a prominent supplier of research reagents, including a wide array of small molecules like liquiritigenin. The company supports biomedical research with products validated for use in various applications, from cancer research to neuroscience.

Research & Development Focus:

• Providing compounds for studying oxidative stress and apoptosis

• Supporting academic and industrial research with reliable, well-characterized products

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Liquiritigenin Market – View in Detailed Research Report

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6️⃣ 5. Jinan Boss Chemical Industry Co., Ltd

Headquarters: Jinan, Shandong, China
Key Offering: Liquiritigenin (Bulk Quantities, 98% Purity)

Jinan Boss Chemical Industry is a specialized manufacturer and supplier of fine chemicals and plant extracts, including liquiritigenin. The company focuses on producing high-quality ingredients for the pharmaceutical, nutraceutical, and cosmetic markets, with an emphasis on competitive pricing and scalable production.

Research & Development Focus:

• Optimization of extraction and purification processes for cost-effective production

• Expansion of product portfolio to include derivative compounds

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5️⃣ 6. Cayman Chemical Company

Headquarters: Ann Arbor, Michigan, USA
Key Offering: Liquiritigenin (≥95% Purity), Screening Libraries & Bioassays

Cayman Chemical is a leader in the supply of biochemical tools for research, offering high-purity liquiritigenin primarily used in pharmacological and toxicological studies. The company is renowned for the quality of its reference standards and assay kits.

Research & Development Focus:

• Providing key compounds for inflammation and cancer research programs

• Development of companion assay kits for compound validation

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4️⃣ 7. TargetMol Chemicals Inc.

Headquarters: Boston, Massachusetts, USA
Key Offering: Liquiritigenin (T6000), Natural Product Libraries

TargetMol specializes in providing a vast collection of bioactive small molecules, including natural products like liquiritigenin, for drug discovery and chemical biology. Their products are widely used in screening campaigns to identify novel therapeutic agents.

Research & Development Focus:

• Curated natural product libraries for high-throughput screening

• Structure-activity relationship (SAR) studies support

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3️⃣ 8. BOC Sciences

Headquarters: Shirley, New York, USA
Key Offering: Liquiritigenin (Custom Synthesis, Bulk Supply)

BOC Sciences offers comprehensive chemical services and products, including the supply of liquiritigenin for research and development. The company provides custom synthesis, formulation, and analytical services tailored to client needs in the pharmaceutical and agrochemical sectors.

Research & Development Focus:

• Custom synthesis of liquiritigenin analogs for proprietary research

• Scale-up services from milligram to kilogram quantities

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2️⃣ 9. Sigma-Aldrich (Merck KGaA)

Headquarters: St. Louis, Missouri, USA
Key Offering: Liquiritigenin (L 8294), Laboratory Reagents & Fine Chemicals

Operating under the Merck Group, Sigma-Aldrich is a cornerstone supplier for the global research community. It offers liquiritigenin with certified purity levels, ensuring reproducibility and reliability for scientific experiments across diverse fields.

Research & Development Focus:

• Support for academic and industrial research with guaranteed purity standards

• Global logistics network for efficient delivery of research chemicals

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1️⃣ 10. Excolla Pharma Inc

Headquarters: Cambridge, Massachusetts, USA
Key Offering: High-Purity Liquiritigenin, Pharmaceutical Intermediates

Excolla Pharma Inc. focuses on the development and supply of high-purity natural compounds and pharmaceutical intermediates. The company positions liquiritigenin as a key ingredient for developing novel therapeutics, particularly in oncology and metabolic diseases.

Research & Development Focus:

• Development of liquiritigenin-based formulations for therapeutic applications

• Collaborative R&D projects with biopharma companies

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Liquiritigenin Market – View in Detailed Research Report

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🌿 Outlook: The Future of Liquiritigenin Lies in Therapeutic Innovation

The liquiritigenin market is experiencing a significant transformation. While its traditional use as a research chemical continues, the compound is gaining prominence as a potential therapeutic agent and a valuable natural ingredient. The industry is investing in advanced extraction technologies, clinical validation, and novel applications to unlock its full potential.

📈 Key Trends Shaping the Market:

• Growing body of preclinical evidence supporting cardioprotective, neuroprotective, and anticancer properties

• Increasing incorporation into nutraceuticals and functional foods for health benefits

• Rising demand for plant-based, sustainable ingredients in the cosmetics and personal care industry

• Advancements in purification technologies enabling higher yield and purity levels at a lower cost

Get Full Report Here:
Liquiritigenin Market – View in Detailed Research Report

The companies listed above are not only supplying a critical research compound—they are actively contributing to the scientific discovery and commercial application of a promising natural molecule.