The Global Polyhexamethylene Guanidine Hydrochloride (PHMG-HCl) Market is projected to grow steadily, driven by its critical role as a potent biocide and disinfectant. This polymer is increasingly vital across applications in water treatment, healthcare, and household cleaning, especially with heightened global focus on hygiene and infection control post-pandemic. The market’s expansion is supported by rising demand for effective and broad-spectrum antimicrobial solutions in public health and industrial sanitation protocols.

As industries worldwide prioritize stringent disinfection standards to ensure safety and compliance, the focus shifts to the key chemical manufacturers driving innovation, supply chain reliability, and product efficacy. In this blog, we profile the Top 10 Companies in the Polyhexamethylene Guanidine Hydrochloride Industry—specialty chemical producers and suppliers shaping the landscape of modern antimicrobial protection.

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🔟 1. Aecochem

Headquarters: Zhangjiagang, China
Key Offering: High-Purity PHMG-HCl (>98%), Custom Synthesis Services

Aecochem is a prominent supplier of fine chemicals and pharmaceutical intermediates, including high-quality Polyhexamethylene Guanidine Hydrochloride. The company serves a global clientele with a focus on rigorous quality control and scalable production capabilities for industrial and sanitary applications.

Innovation & Market Focus:

• Custom synthesis for specific antimicrobial formulations

• Focus on high-purity grades for sensitive applications

• Expanding distribution networks in North America and Europe

Download FREE Sample Report: Polyhexamethylene Guanidine Hydrochloride Market – View in Detailed Research Report

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9️⃣ 2. BOC Sciences

Headquarters: Shirley, New York, USA
Key Offering: PHMG-HCl for Research, Pharmaceutical, and Biocidal Applications

BOC Sciences provides life science chemicals and materials, offering Polyhexamethylene Guanidine Hydrochloride primarily to research institutions, pharmaceutical developers, and specialty chemical sectors. Their strength lies in supporting R&D and small-to-medium scale production with high analytical standards.

Innovation & Market Focus:

• Supplies PHMG-HCl for academic and industrial R&D

• Provides technical data and material safety support

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8️⃣ 3. Hangzhou Meite Chemical

Headquarters: Hangzhou, Zhejiang, China
Key Offering: Industrial-grade and Purified PHMG-HCl

Hangzhou Meite Chemical specializes in the manufacturing of guanidine series products, including PHMG-HCl. The company has established a strong presence in the Asian market, supplying compounds for water treatment, textiles, and disinfectant products.

Innovation & Market Focus:

• Integrated production from raw materials to finished PHMG-HCl

• Cost-effective solutions for large-volume industrial users

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7️⃣ 4. Leap Labchem

Headquarters: Fujian, China
Key Offering: PHMG-HCL, Lab Chemicals, and Custom Manufacturing

Leap Labchem is a chemical supplier focused on providing high-purity chemicals for laboratory and industrial use. Their PHMG-HCl products are used in formulation of disinfectants, preservatives, and antimicrobial coatings.

Innovation & Market Focus:

• Emphasis on purity and batch-to-batch consistency

• Serves emerging markets in Southeast Asia and the Middle East

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6️⃣ 5. Ningbo EST Chemical

Headquarters: Ningbo, Zhejiang, China
Key Offering: PHMG-HCl, Surfactants, and Specialty Chemical Intermediates

Ningbo EST Chemical is engaged in the production and export of various chemical intermediates, with PHMG-HCl being a key product in their biocides portfolio. The company caters to manufacturers of cleaning agents, water treatment chemicals, and hygiene products.

Innovation & Market Focus:

• Development of blended formulations incorporating PHMG-HCl

• Robust export operations to global markets

Download FREE Sample Report: Polyhexamethylene Guanidine Hydrochloride Market – View in Detailed Research Report

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5️⃣ 6. Xiamen Hisunny Chemical

Headquarters: Xiamen, Fujian, China
Key Offering: PHMG-HCl, Fine Chemicals for Disinfection and Preservation

Xiamen Hisunny Chemical specializes in fine chemicals with a focus on antimicrobial agents. They supply PHMG-HCl to industries requiring effective microbiological control, such as paint preservation, cosmetic preservation, and material protection.

Innovation & Market Focus:

• Targeted solutions for material preservation and antimicrobial coatings

• Strong expertise in regulatory compliance for biocidal products

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4️⃣ 7. IRO GROUP

Headquarters: Qingdao, Shandong, China
Key Offering: PHMG-HCl, Water Treatment Chemicals, Disinfectant Raw Materials

IRO GROUP is a diversified chemical company with a significant focus on water treatment and disinfection chemicals. Their production of PHMG-HCl supports applications in cooling water systems, swimming pools, and surface disinfection.

Innovation & Market Focus:

• Integration of PHMG-HCl into comprehensive water treatment programs

• Focus on sustainable and effective biocidal solutions

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3️⃣ 8. Hunan Lijie Biochemical

Headquarters: Changsha, Hunan, China
Key Offering: High-Purity PHMG-HCl, Guanidine Salts, Biocides

Hunan Lijie Biochemical specializes in the research, development, and production of guanidine-based chemicals. They are a key manufacturer of PHMG-HCl, emphasizing product quality and application support for industrial and sanitary sectors.

Innovation & Market Focus:

• Investment in R&D for novel guanidine polymer applications

• Strategic partnerships with disinfectant manufacturers globally

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2️⃣ 9. Spectrum Chemical Mfg. Corp.

Headquarters: New Brunswick, New Jersey, USA
Key Offering: USP/NF, FCC, BP, EP Grade Chemicals, including PHMG-HCl for Pharma & Research

Spectrum Chemical is a leading global supplier of high-purity fine chemicals. While not a primary manufacturer of PHMG-HCl, they are a critical distributor of the compound for pharmaceutical, research, and high-specification industrial applications, ensuring compliance with major pharmacopeias.

Innovation & Market Focus:

• Supply of certified high-purity PHMG-HCl for regulated industries

• Global logistics and quality assurance for critical applications

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1️⃣ 10. Tokyo Chemical Industry Co., Ltd. (TCI)

Headquarters: Tokyo, Japan
Key Offering: High-Purity PHMG-HCl for Research, Laboratory, and Specialty Synthesis

TCI is a global manufacturer and supplier of laboratory chemicals and high-purity organic compounds. They provide PHMG-HCl primarily to the research community, pharmaceutical companies, and developers of advanced materials, focusing on exceptional purity and detailed product characterization.

Innovation & Market Focus:

• Serving the R&D sector with high-quality reference standards

• Driving innovation in new antimicrobial material science

Read Full Report: Polyhexamethylene Guanidine Hydrochloride Market – View in Detailed Research Report

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🧪 Outlook: The Future of PHMG-HCl is Efficacy and Regulation

The Polyhexamethylene Guanidine Hydrochloride market is navigating a landscape defined by persistent demand for effective disinfection alongside evolving regulatory frameworks. While its efficacy against a broad spectrum of microorganisms is well-established, the industry is increasingly focused on safe handling, environmental impact, and application-specific formulations.

📈 Key Trends Shaping the Market:

• Stringent global regulations for biocide approval and usage (e.g., EPA, ECHA)

• Growing demand in emerging economies for public health and water treatment infrastructure

• Research into novel delivery systems and synergistic blends to enhance efficacy and safety

• Increased focus on material preservation in industries like paints, textiles, and plastics

Read Full Report: Polyhexamethylene Guanidine Hydrochloride Market – View in Detailed Research Report

The companies profiled above are not only supplying a critical antimicrobial agent—they are enabling advanced hygiene solutions for a safer world.