The Global 1,4-Diisocyanatobutane Market was valued at US$ 182.5 Million in 2024 and is projected to reach US$ 248.3 Million by 2029, growing at a Compound Annual Growth Rate (CAGR) of 6.3% during the forecast period (2024–2029). This significant growth is fueled by the expanding applications of polyurethanes in the biomedical sector, increasing demand for specialty adhesives and coatings, and advancements in polymer science driving the need for high-purity chemical intermediates.

As industries worldwide increasingly adopt advanced polymer materials for high-performance applications, the focus intensifies on the chemical manufacturers at the forefront of producing critical raw materials. In this analysis, we profile the Top 10 Companies in the 1,4-Diisocyanatobutane Industry—specialty chemical producers and innovators who are essential to supply chains in biomedical science, electronics, and advanced manufacturing.

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🔟 1. BASF SE

Headquarters: Ludwigshafen, Germany
Key Offering: High-Purity 1,4-Diisocyanatobutane, Polyurethane Prepolymers

BASF is a global leader in the chemical industry and a major supplier of isocyanate derivatives. The company produces high-purity 1,4-Diisocyanatobutane, which serves as a critical building block for specialty polyurethanes used in medical devices, elastomers, and coatings.

Innovation Initiatives:

• Development of biocompatible polyurethanes for medical implants

• Investment in sustainable production processes for isocyanates

• Strategic partnerships with medical device manufacturers

Download FREE Sample Report: 1,4-Diisocyanatobutane Market – View in Detailed Research Report

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9️⃣ 2. Covestro AG

Headquarters: Leverkusen, Germany
Key Offering: 1,4-Diisocyanatobutane, Aliphatic Isocyanates, Specialty Polyols

Covestro, a spin-off from Bayer, is a world-leading supplier of high-performance polymers. The company’s advanced isocyanate portfolio includes 1,4-Diisocyanatobutane, which is essential for producing light-stable and chemically resistant polyurethanes for demanding applications.

Innovation Initiatives:

• Focus on medical-grade polyurethanes with enhanced biocompatibility

• R&D in recyclable and sustainable polyurethane systems

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8️⃣ 3. Mitsui Chemicals, Inc.

Headquarters: Tokyo, Japan
Key Offering: Takeda™ 1,4-Diisocyanatobutane, High-Functionality Polymers

Mitsui Chemicals is a key player in the Asian chemical market, producing high-purity 1,4-Diisocyanatobutane under its Takeda brand. The company serves diverse industries including healthcare, automotive, and electronics with its specialized isocyanate products.

Innovation Initiatives:

• Expansion of production capacity for high-purity diisocyanates

• Development of custom polyurethane formulations for medical applications

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7️⃣ 4. TCI Chemicals (Tokyo Chemical Industry Co., Ltd.)

Headquarters: Tokyo, Japan
Key Offering: Laboratory Grade 1,4-Diisocyanatobutane, Research Chemicals

TCI Chemicals is a leading global supplier of high-purity laboratory chemicals, including 1,4-Diisocyanatobutane for research and development purposes. The company provides critical materials to academic institutions, pharmaceutical companies, and industrial R&D centers worldwide.

Innovation Initiatives:

• Continuous expansion of specialty chemical portfolio

• Support for academic research in polymer science and biomaterials

Download FREE Sample Report: 1,4-Diisocyanatobutane Market – View in Detailed Research Report

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6️⃣ 5. Merck KGaA

Headquarters: Darmstadt, Germany
Key Offering: Sigma-Aldrich Brand 1,4-Diisocyanatobutane, Life Science Reagents

Merck KGaA, through its Sigma-Aldrich brand, is a premier supplier of high-purity chemicals for life sciences and high-tech industries. The company offers 1,4-Diisocyanatobutane that meets stringent quality standards for pharmaceutical and biomedical research applications.

Innovation Initiatives:

• Investment in cGMP-compliant manufacturing facilities

• Development of analytical standards and certified reference materials

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5️⃣ 6. VWR International, LLC (Part of Avantor)

Headquarters: Radnor, Pennsylvania, USA
Key Offering: 1,4-Diisocyanatobutane, Laboratory Supplies & Equipment

VWR International, a part of Avantor, distributes 1,4-Diisocyanatobutane and other specialty chemicals to research laboratories and industrial customers globally. The company’s extensive distribution network ensures reliable supply to the scientific community.

Innovation Initiatives:

• Global logistics optimization for chemical distribution

• Digital platforms for streamlined chemical procurement

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4️⃣ 7. Santa Cruz Biotechnology, Inc.

Headquarters: Dallas, Texas, USA
Key Offering: Research-Grade 1,4-Diisocyanatobutane, Biochemicals

Santa Cruz Biotechnology is a leading supplier of research chemicals, antibodies, and biochemicals. The company provides high-purity 1,4-Diisocyanatobutane to support research in polymer chemistry, materials science, and biomedical engineering.

Innovation Initiatives:

• Expansion of chemical product portfolio for research applications

• Quality assurance programs for research chemical purity

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3️⃣ 8. Alfa Aesar (Thermo Fisher Scientific)

Headquarters: Ward Hill, Massachusetts, USA
Key Offering: 1,4-Diisocyanatobutane, Metals, Materials & Chemicals

Alfa Aesar, part of Thermo Fisher Scientific, is a leading manufacturer and supplier of research chemicals, including high-purity 1,4-Diisocyanatobutane. The company serves pharmaceutical, academic, and industrial research markets with comprehensive chemical solutions.

Innovation Initiatives:

• Integration with Thermo Fisher’s global distribution network

• Development of specialized chemical formulations for emerging applications

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2️⃣ 9. Actu-All Chemicals

Headquarters: Baroda, Gujarat, India
Key Offering: Industrial Grade 1,4-Diisocyanatobutane, Custom Synthesis

Actu-All Chemicals is a specialized manufacturer and supplier of fine chemicals and pharmaceutical intermediates, including 1,4-Diisocyanatobutane. The company has established itself as a reliable source for industrial-grade isocyanates in the Asian market.

Innovation Initiatives:

• Scale-up capabilities for custom chemical synthesis

• Focus on cost-effective production of specialty chemicals

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1️⃣ 10. BOC Sciences

Headquarters: Shirley, New York, USA
Key Offering: 1,4-Diisocyanatobutane, Pharmaceutical Intermediates, Custom Synthesis

BOC Sciences is a global chemical supplier specializing in the manufacturing and distribution of research chemicals, pharmaceutical intermediates, and custom synthesis services. The company provides high-quality 1,4-Diisocyanatobutane to research and industrial customers worldwide.

Innovation Initiatives:

• Custom synthesis services for specialized chemical compounds

• Global supply chain management for chemical distribution

Get Full Report Here: 1,4-Diisocyanatobutane Market – View in Detailed Research Report

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🔬 Outlook: The Future of 1,4-Diisocyanatobutane in Advanced Materials

The 1,4-Diisocyanatobutane market is experiencing transformative growth as emerging applications in biomedicine and advanced materials create new demand drivers. While traditional industrial applications continue to dominate volume consumption, the industry is investing significantly in high-purity grades and specialized formulations for next-generation applications.

📈 Key Trends Shaping the Market:

• Rising demand for biocompatible polymers in medical devices and implants

• Increasing applications in flexible electronics and advanced coatings

• Growing emphasis on sustainable and recyclable polyurethane systems

• Expansion of custom synthesis services for specialized applications

Get Full Report Here: 1,4-Diisocyanatobutane Market – View in Detailed Research Report

The companies profiled above are not only supplying essential chemical intermediates—they’re enabling the next generation of advanced materials across multiple high-tech industries.