The Global Sodium 3-Hydroxybutyrate Market was valued at USD 45.2 Million in 2023 and is projected to reach USD 89.7 Million by 2028, growing at a Compound Annual Growth Rate (CAGR) of 14.7% during the forecast period (2023–2028). This robust growth is being fueled by the expanding application of exogenous ketones in weight management protocols, the rising demand for high-performance sports nutrition, and increasing consumer awareness of the benefits associated with ketogenic diets.

As the health and wellness sector increasingly embraces metabolic health solutions, the focus shifts to the key ingredient manufacturers and suppliers who are pioneering the development and distribution of high-purity Sodium 3-Hydroxybutyrate. In this blog, we profile the Top 10 Companies in the Sodium 3-Hydroxybutyrate Industry—a dynamic mix of established chemical manufacturers and specialized biopharma firms shaping the future of ketone supplementation.

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2023-2028 Global and Regional Sodium 3-Hydroxybutyrate Industry Status and Prospects Professional Market – View in Detailed Research Report

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🔟 1. NNB

Headquarters: Zhangjiagang, China
Key Offering: High-Purity Sodium 3-Hydroxybutyrate (Purity ≥98%, Purity<98%)

NNB is a prominent supplier of fine chemicals and nutritional ingredients, including Sodium 3-Hydroxybutyrate. The company has established a strong presence in the global market by focusing on consistent quality and scalable production capabilities to meet the growing demand from the supplement industry.

Key Strengths & Market Focus:

• Robust manufacturing infrastructure for bulk ingredient supply

• Strategic focus on the Asia-Pacific dietary supplement market

• Commitment to meeting international quality and safety standards (GMP, ISO)

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9️⃣ 2. Shanghai Kangxin

Headquarters: Shanghai, China
Key Offering: Pharmaceutical and Nutraceutical Grade Sodium 3-Hydroxybutyrate

Shanghai Kangxin specializes in the research, development, and production of advanced pharmaceutical intermediates and nutraceutical ingredients. Their expertise in chemical synthesis positions them as a key player for high-grade Sodium 3-Hydroxybutyrate used in clinical research and premium supplement formulations.

Key Strengths & Market Focus:

• Advanced R&D capabilities for process optimization and purity enhancement

• Strong distribution network catering to both domestic and international clients

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8️⃣ 3. Anhui Integrity Biopharm

Headquarters: Hefei, Anhui, China
Key Offering: Sodium 3-Hydroxybutyrate for Weight Control and Sports Nutrition

Anhui Integrity Biopharm is dedicated to the production of bioactive compounds and pharmaceutical raw materials. The company has made significant investments in scaling up its Sodium 3-Hydroxybutyrate production to serve the rapidly expanding global market for ketogenic supplements.

Key Strengths & Market Focus:

• Integrated production from raw materials to finished high-purity products

• Focus on cost-effective manufacturing to improve market accessibility

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7️⃣ 4. JingYao Biotechnology

Headquarters: Taizhou, Jiangsu, China
Key Offering: Sodium 3-Hydroxybutyrate, Ketone Salts, and Custom Formulations

JingYao Biotechnology is a specialized manufacturer with a core focus on ketone body supplements. The company offers a range of ketone salts and is recognized for its technical expertise in developing formulations tailored for specific applications in sports performance and metabolic health.

Key Strengths & Market Focus:

• Specialization in ketone-based product development

• Collaborations with sports nutrition brands for custom ingredient solutions

Download FREE Sample Report:
2023-2028 Global and Regional Sodium 3-Hydroxybutyrate Industry Status and Prospects Professional Market – View in Detailed Research Report

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6️⃣ 5. Shijiazhuang Chirals Chemical

Headquarters: Shijiazhuang, Hebei, China
Key Offering: Chiral Compounds and Specialty Chemicals including Sodium 3-Hydroxybutyrate

Shijiazhuang Chirals Chemical leverages its expertise in chiral chemistry to produce high-purity Sodium 3-Hydroxybutyrate. The company serves a diverse clientele, including pharmaceutical companies and nutraceutical brands requiring stringent quality control.

Key Strengths & Market Focus:

• Expertise in the synthesis of stereochemically pure compounds

• Supplies intermediates for pharmaceutical research beyond nutraceuticals

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5️⃣ 6. Cayman Chemical

Headquarters: Ann Arbor, Michigan, USA
Key Offering: High-Purity Biochemicals for Research, including Sodium 3-Hydroxybutyrate

Cayman Chemical is a leading global supplier of biochemicals for research and development. While not a bulk manufacturer, the company is critical for providing high-purity, research-grade Sodium 3-Hydroxybutyrate used in academic studies, clinical trials, and early-stage product development, thereby validating the ingredient’s efficacy and safety.

Key Strengths & Market Focus:

• Reputation for supplying ultra-high-purity compounds for scientific research

• Essential partner for universities and R&D departments validating ketone applications

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4️⃣ 7. Sigma-Aldrich (Merck KGaA)

Headquarters: Darmstadt, Germany
Key Offering: Laboratory Chemicals and Analytical Standards, including Sodium 3-Hydroxybutyrate

As part of Merck KGaA, Sigma-Aldrich is a fundamental supplier to the global scientific community. The company provides certified reference standards and high-purity Sodium 3-Hydroxybutyrate, which are indispensable for quality control testing, method development, and regulatory compliance within the supplement manufacturing industry.

Key Strengths & Market Focus:

• Global distribution network ensuring reliable supply for analytical and R&D purposes

• Provision of certified reference materials that set industry benchmarks for quality

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3️⃣ 8. TCI Chemicals

Headquarters: Tokyo, Japan
Key Offering: Fine Chemicals and Reagents, including Sodium 3-Hydroxybutyrate

Tokyo Chemical Industry (TCI) is a major international supplier of high-quality fine chemicals. TCI offers Sodium 3-Hydroxybutyrate primarily for research institutions and companies conducting foundational studies on ketone metabolism, contributing to the scientific backbone of the industry.

Key Strengths & Market Focus:

• Extensive catalog of over 30,000 products supporting diverse research needs

• Strong reputation for purity and consistency in the scientific supply chain

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2️⃣ 9. Alta Laboratories

Headquarters: Hyderabad, India
Key Offering: Pharmaceutical Intermediates and Nutraceutical Ingredients

Alta Laboratories is an emerging player in the active pharmaceutical ingredient (API) and nutraceutical space. The company is increasingly focusing on metabolic health ingredients, including Sodium 3-Hydroxybutyrate, aiming to capture growth in the cost-sensitive markets of South Asia and the Middle East.

Key Strengths & Market Focus:

• Competitive manufacturing costs benefiting price-sensitive markets

• Strategic expansion into the growing wellness and preventive healthcare sector

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1️⃣ 10. BOC Sciences

Headquarters: Shirley, New York, USA
Key Offering: Chemical Products and Custom Synthesis Services

BOC Sciences operates as a comprehensive supplier and service provider in the chemical industry. The company offers Sodium 3-Hydroxybutyrate and provides custom synthesis services for brands looking to develop proprietary ketone formulations or require specific quantities for product development.

Key Strengths & Market Focus:

• Flexible custom synthesis and manufacturing services for niche requirements

• Strong online presence and customer-centric supply model

Read Full Report:
2023-2028 Global and Regional Sodium 3-Hydroxybutyrate Industry Status and Prospects Professional Market – View in Detailed Research Report

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🌍 Outlook: The Future of Sodium 3-Hydroxybutyrate Is Personalized and Application-Driven

The Sodium 3-Hydroxybutyrate market is experiencing a paradigm shift from a niche supplement to a mainstream ingredient. While its use in sports nutrition remains a primary driver, new therapeutic and lifestyle applications are creating significant growth avenues, supported by ongoing clinical research.

📈 Key Trends Shaping the Market:

• Expansion into Therapeutic Areas: Growing research into applications for neurological health, metabolic disorders, and endurance athletics.

• Product Formulation Innovation: Development of improved delivery formats such as powders, ready-to-drink beverages, and capsules to enhance user compliance and bioavailability.

• Regulatory Scrutiny and Standardization: Increasing focus on quality control, purity standards, and clear labeling to build consumer trust and ensure product safety.

• Geographical Market Expansion: Rising disposable incomes and health awareness in emerging economies of Asia-Pacific and Latin America are opening new consumer bases.

Read Full Report:
2023-2028 Global and Regional Sodium 3-Hydroxybutyrate Industry Status and Prospects Professional Market – View in Detailed Research Report

The companies leading the Sodium 3-Hydroxybutyrate market are not just supplying an ingredient—they are enabling a new frontier in metabolic health and human performance.