The Global Biocatalysis and Biocatalysts Market was valued at USD 6.8 Billion in 2023 and is projected to reach USD 12.1 Billion by 2030, growing at a Compound Annual Growth Rate (CAGR) of 8.5% during the forecast period (2024–2030). This robust growth is being propelled by increasing demand for sustainable manufacturing processes, stringent environmental regulations, and the expanding application of enzymes across the pharmaceutical, food and beverage, and biofuel industries.

As industries worldwide pivot towards greener and more efficient production methods, biocatalysis—the use of natural catalysts like enzymes to accelerate chemical reactions—has emerged as a transformative technology. In this blog, we profile the Top 10 Companies in the Biocatalysis and Biocatalysts Industry, highlighting the innovators and market leaders who are engineering the biological tools for a more sustainable future.

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🔟 1. Novozymes A/S

Headquarters: Bagsværd, Denmark
Key Offering: A wide portfolio of industrial enzymes including proteases, lipases, carbohydrases, and phytases.

Novozymes is the undisputed global leader in the industrial enzymes market, holding a significant share of the biocatalysis sector. The company’s solutions are critical in over 30 industries, enabling customers to reduce energy consumption, waste, and raw material usage. Their R&D focuses on discovering and optimizing enzymes for complex biochemical processes.

Sustainability and Innovation Initiatives:

• Pioneering enzyme technologies for advanced biofuels and bioplastics

• Strategic partnerships with major players in the agriculture, food, and energy sectors

• Committed to enabling a circular bioeconomy through biological solutions

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9️⃣ 2. BASF SE

Headquarters: Ludwigshafen, Germany
Key Offering: Specialty enzymes, bio-based chemicals, and tailored biocatalysis solutions.

BASF, a global chemical giant, has integrated biocatalysis as a core component of its white (industrial) biotechnology division. The company leverages enzymes for the sustainable production of vitamins, aroma chemicals, and active pharmaceutical ingredients (APIs), offering a competitive alternative to traditional chemical synthesis.

Sustainability and Innovation Initiatives:

• Development of proprietary enzyme cascades for complex molecule synthesis

• Investment in bio-acrylic acid and other bio-based platform chemicals

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8️⃣ 3. DuPont de Nemours, Inc.

Headquarters: Wilmington, Delaware, USA
Key Offering: Industrial enzymes for food, feed, and fuel applications under the Danisco brand.

Following its acquisition of Danisco, DuPont possesses one of the world’s most extensive enzyme portfolios. Its biocatalysts are essential in baking, brewing, animal nutrition, and bioethanol production, driving efficiency and sustainability for a global customer base.

Sustainability and Innovation Initiatives:

• Leading provider of enzymes for second-generation (cellulosic) biofuels

• Focus on developing high-performance enzymes that reduce water and energy use in manufacturing

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7️⃣ 4. Codexis, Inc.

Headquarters: Redwood City, California, USA
Key Offering: Engineered enzymes and biocatalytic processes for pharmaceuticals and fine chemicals.

Codexis specializes in using its proprietary protein engineering platform, CodeEvolver®, to design novel enzymes that traditional discovery methods cannot find. The company is a key enabler for the pharmaceutical industry, providing cleaner and more efficient routes to complex drug molecules.

Sustainability and Innovation Initiatives:

• Strategic collaborations with major pharma companies to develop greener manufacturing processes

• Development of biocatalysts for RNAi therapeutics and other novel modalities

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6️⃣ 5. Royal DSM

Headquarters: Heerlen, Netherlands
Key Offering: Enzymes for human and animal nutrition, personal care, and bio-based materials.

DSM is a purpose-led global science company with a strong foothold in health and nutrition. Its biocatalysis segment focuses on developing enzymes that improve digestive health, food quality, and the sustainability profile of various consumer products.

Sustainability and Innovation Initiatives:

• Launch of enzyme solutions to reduce methane emissions from cattle

• Commitment to creating 100% bio-based and recyclable materials

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Biocatalysis and Biocatalysts Market – View in Detailed Research Report

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5️⃣ 6. Amano Enzyme Inc.

Headquarters: Nagoya, Japan
Key Offering: Specialty enzymes for food processing, pharmaceutical intermediates, and diagnostics.

Amano Enzyme is a leading Japanese enzyme manufacturer with a reputation for high-quality and niche enzyme products. The company serves global markets with enzymes tailored for specific reactions in starch processing, dairy, and diagnostic kits.

Sustainability and Innovation Initiatives:

• Focus on R&D for transglutaminase and other food texture-modifying enzymes

• Expansion of production capacity to meet growing Asian market demand

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4️⃣ 7. AB Enzymes GmbH

Headquarters: Darmstadt, Germany
Key Offering: Enzymes for the food, feed, and beverage industries.

A subsidiary of Associated British Foods, AB Enzymes is a major European player with deep expertise in bakery, animal feed, and alcohol production enzymes. The company’s products help improve yield, quality, and shelf-life for its industrial customers.

Sustainability and Innovation Initiatives:

• Development of enzymes that reduce baking time and energy consumption

• Solutions to enhance the nutritional value of animal feed, reducing waste

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3️⃣ 8. Chr. Hansen Holding A/S

Headquarters: Hørsholm, Denmark
Key Offering: Microbial and enzyme solutions primarily for the food industry.

While best known for its microbial cultures, Chr. Hansen is a significant player in enzymes, particularly in the dairy sector for cheese production and in preventing food waste. The company leverages its strong microbial science platform to develop integrated biological solutions.

Sustainability and Innovation Initiatives:

• Enzymes for natural food preservation, reducing the need for chemical additives

• Commitment to helping customers reduce food loss through extended shelf-life solutions

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2️⃣ 9. Thermo Fisher Scientific Inc.

Headquarters: Waltham, Massachusetts, USA
Key Offering: High-purity enzymes for life science research, diagnostics, and bioprocessing.

Through its Thermo Scientific brand, the company is a leading supplier of restriction enzymes, polymerases, and other molecular biology tools. These biocatalysts are fundamental to genetic engineering, PCR, and biomanufacturing workflows in labs worldwide.

Sustainability and Innovation Initiatives:

• Providing essential tools for the development of biologics and cell & gene therapies

• Focus on reproducibility and quality for critical research and manufacturing applications

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1️⃣ 10. Megazyme Ltd. (A subsidiary of Neogen Corporation)

Headquarters: Bray, Ireland
Key Offering: Analytical-grade enzymes and test kits for food and feed analysis.

Megazyme is a specialist provider of high-purity enzymes used primarily in analytical testing to measure components like dietary fiber, starch, and beta-glucan. Its products are the international standard for quality control in the food and agricultural industries.

Sustainability and Innovation Initiatives:

• Development of accurate and reliable test methods that ensure food labeling integrity

• Supporting global food safety and nutritional standards through precise enzymatic analysis

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Biocatalysis and Biocatalysts Market – View in Detailed Research Report

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🌍 Outlook: The Future of Biocatalysis Is Personalized and Precision-Driven

The biocatalysis and biocatalysts market is undergoing a fundamental transformation. While hydrolytic enzymes like proteases and carbohydrases still dominate the market volume, the industry is rapidly advancing towards engineered enzymes for stereoselective synthesis, carbon capture, and plastic degradation.

📈 Key Trends Shaping the Market:

• Protein Engineering Revolution: AI and machine learning are accelerating the design of enzymes with novel functions and enhanced stability.

• Pharmaceutical Dominance: The shift towards chiral APIs and complex molecules is driving high-value biocatalysis adoption in drug manufacturing.

• Circular Economy Drive: Enzymes are key to upcycling waste plastics and biomass into valuable chemicals, aligning with global sustainability goals.

• Regulatory Tailwinds: Government policies favoring green chemistry and bio-based products are creating a favorable environment for market growth.

Get Full Report Here:
Biocatalysis and Biocatalysts Market – View in Detailed Research Report

The companies listed above are not just supplying enzymes—they are providing the biological toolkit that is essential for building a more sustainable and efficient industrial landscape.