The Global Hyodeoxycholic Acid Market was valued at US$ 98.5 Million in 2024 and is projected to reach US$ 142.3 Million by 2030, growing at a Compound Annual Growth Rate (CAGR) of 6.2% during the forecast period (2024–2030). This significant growth is driven by the increasing demand for pharmaceutical intermediates, the expanding application of bile acids in health supplements, and the rising focus on liver health therapeutics globally.

As the pharmaceutical and nutraceutical industries intensify their research into metabolic and digestive health solutions, the spotlight is on the key producers who are ensuring a reliable supply of high-purity active pharmaceutical ingredients (APIs). In this blog, we profile the Top 10 Companies in the Hyodeoxycholic Acid Industry—a mix of established chemical manufacturers, specialized bile acid producers, and innovative API suppliers shaping the future of therapeutic and wellness applications.

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🔟 1. ICE Group

Headquarters: Milan, Italy
Key Offering: High-Purity Hyodeoxycholic Acid (98% and 99% grades)

ICE Group is a leading European supplier of fine chemicals and pharmaceutical intermediates, with a strong reputation for quality and consistency in Hyodeoxycholic Acid production. The company serves major pharmaceutical clients worldwide, providing materials critical for synthesizing advanced therapeutic agents.

Key Strengths and Initiatives:

• Stringent quality control compliant with major pharmacopeias (USP, EP)

• Strategic partnerships with global pharmaceutical corporations

• Investment in green chemistry and sustainable manufacturing processes

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Hyodeoxycholic Acid Market – View in Detailed Research Report

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9️⃣ 2. PharmaZell GmbH

Headquarters: Raubling, Germany
Key Offering: Pharmaceutical-grade Hyodeoxycholic Acid, Custom Synthesis

PharmaZell GmbH is a globally recognized leader in the development and manufacturing of complex APIs, including niche bile acids. Their expertise in steroid chemistry positions them as a key partner for innovator pharmaceutical companies requiring high-purity Hyodeoxycholic Acid for drug development.

Key Strengths and Initiatives:

• Dedicated R&D center for bile acid derivatives

• cGMP certified manufacturing facilities

• Focus on developing novel synthetic pathways for improved efficiency

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8️⃣ 3. Daewoong

Headquarters: Seoul, South Korea
Key Offering: Hyodeoxycholic Acid APIs, Pharmaceutical Intermediates

Daewoong is a major South Korean pharmaceutical company with a robust chemical division that produces a wide range of APIs. Their production of Hyodeoxycholic Acid supports both domestic and international markets, particularly in Asia where demand for liver health products is growing rapidly.

Key Strengths and Initiatives:

• Integrated production from raw materials to finished APIs

• Strong distribution network across Asia-Pacific regions

• Investment in bio-fermentation technologies as an alternative to extraction

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7️⃣ 4. Dipharma Francis

Headquarters: Milan, Italy
Key Offering: High-Purity HDCA, Customized Bile Acid Salts

Dipharma Francis specializes in the production of active ingredients for the pharmaceutical industry, with a strong focus on steroids and bile acids. The company’s technical expertise allows it to offer both standard and customized forms of Hyodeoxycholic Acid to meet specific customer formulation requirements.

Key Strengths and Initiatives:

• Advanced purification technologies for ultra-high purity grades

• Long-standing relationships with leading gastroenterology drug manufacturers

• Commitment to regulatory excellence and international compliance

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Hyodeoxycholic Acid Market – View in Detailed Research Report

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6️⃣ 5. Suzhou Tianlu

Headquarters: Suzhou, China
Key Offering: Hyodeoxycholic Acid (98% and 99%), Bile Acid Extracts

Suzhou Tianlu is a prominent Chinese manufacturer specializing in bile acid products derived from animal sources. The company leverages China’s significant resources in animal bile extraction to produce cost-effective Hyodeoxycholic Acid for both pharmaceutical and health product applications.

Key Strengths and Initiatives:

• Large-scale extraction and purification capabilities

• Competitive pricing strategy for volume buyers

• Expanding international market presence through strategic exports

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5️⃣ 6. Henan Liwei Biological

Headquarters: Zhengzhou, China
Key Offering: Plant-derived Bile Acids, HDCA for Nutraceuticals

Henan Liwei Biological focuses on biological products and extracts, with a growing portfolio in bile acids. The company is exploring innovative approaches to Hyodeoxycholic Acid production, including potential plant-based sources to address sourcing and sustainability concerns.

Key Strengths and Initiatives:

• Research into alternative sourcing and synthetic biology methods

• Strong focus on the nutraceutical and health supplement markets

• Cost-effective production models for high-volume applications

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4️⃣ 7. Zhongshan Belling

Headquarters: Zhongshan, China
Key Offering: Pharmaceutical Intermediates, Hyodeoxycholic Acid

Zhongshan Belling is a chemical manufacturer with expertise in steroid and bile acid chemistry. The company serves as an important supplier in the Asian market, providing intermediates to pharmaceutical companies developing drugs for metabolic disorders and liver diseases.

Key Strengths and Initiatives:

• Strategic location in China’s major chemical manufacturing hub

• Continuous process optimization for yield improvement

• Focus on meeting the specific quality standards of international clients

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3️⃣ 8. Tianjin NWS

Headquarters: Tianjin, China
Key Offering: Fine Chemicals, HDCA for Research and Development

Tianjin NWS manufactures and supplies fine chemicals to the pharmaceutical and research sectors. Their Hyodeoxycholic Acid products are used by research institutions and smaller pharmaceutical companies requiring high-quality materials for drug discovery and development.

Key Strengths and Initiatives:

• Flexible manufacturing for small to medium batch sizes

• Strong customer service and technical support for research clients

• Adapting to evolving regulatory requirements in different markets

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2️⃣ 9. Aktin Chemicals

Headquarters: Chengdu, China
Key Offering: High-Purity Bile Acids, Custom Synthesis Services

Aktin Chemicals specializes in the production of steroid compounds and bile acids, with a focus on serving the global research and pharmaceutical markets. The company has built a reputation for reliability and consistency in Hyodeoxycholic Acid supply.

Key Strengths and Initiatives:

• Technical expertise in complex organic synthesis

• Ability to produce custom derivatives and analogs

• Investment in analytical capabilities for quality assurance

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1️⃣ 10. Chengdu Organic Chemicals

Headquarters: Chengdu, China
Key Offering: Research-grade Hyodeoxycholic Acid, Biochemical Reagents

Chengdu Organic Chemicals, affiliated with the Chinese Academy of Sciences, is a leading supplier of biochemical reagents and fine chemicals. The company provides high-purity Hyodeoxycholic Acid primarily to academic institutions, research organizations, and pharmaceutical companies for investigative studies.

Key Strengths and Initiatives:

• Strong academic and research foundation

• Focus on purity and consistency for research applications

• Collaborations with research institutions on bile acid applications

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Hyodeoxycholic Acid Market – View in Detailed Research Report

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🔬 Outlook: The Future of Hyodeoxycholic Acid Is Research-Driven and Application-Diverse

The Hyodeoxycholic Acid market is undergoing a significant transformation. While traditional pharmaceutical applications continue to dominate, new research is unlocking potential uses in metabolic health, microbiome modulation, and even oncology, driving innovation across the supply chain.

📈 Key Trends Shaping the Market:

• Increasing research into bile acid receptors (FXR, TGR5) and their therapeutic potential

• Growing demand for high-purity ingredients in pharmaceutical formulations

• Expansion of the nutraceutical sector and consumer interest in digestive health

• Technological advancements in purification and synthetic biology production methods

Get Full Report Here:
Hyodeoxycholic Acid Market – View in Detailed Research Report

The companies listed above are not only supplying a critical pharmaceutical intermediate—they’re enabling cutting-edge research and therapeutic innovation in metabolic health and beyond.