Top 10 Companies in the Rolipram Market (2025): Key Suppliers Fueling Pharmaceutical Innovation

In Business Insights
December 01, 2025



The Global Rolipram Market was valued at US$ 12.8 Million in 2024 and is projected to reach US$ 18.3 Million by 2029, growing at a Compound Annual Growth Rate (CAGR) of 5.8% during the forecast period (2024–2029). This growth is being driven by increasing research into novel therapeutics for neurological and inflammatory diseases, rising demand for high-purity research chemicals, and the expanding pipeline of PDE4 inhibitor-based drug candidates across global pharmaceutical and biotechnology sectors.

As the life sciences industry accelerates its focus on targeted therapies for complex conditions, the demand for critical research compounds like Rolipram is intensifying. This blog profiles the Top 10 Companies in the Rolipram Market—specialty chemical manufacturers, biotech suppliers, and research reagent specialists who are enabling breakthroughs in neuroscience, immunology, and oncology research.

Download FREE Sample Report:
Rolipram Market – View in Detailed Research Report


🔟 1. Adooq Bioscience

Headquarters: Irvine, California, USA
Key Offering: High-purity Rolipram (≥98%, ≥99%), Research-grade compounds

Adooq Bioscience is a leading supplier of small molecule inhibitors for research, including a comprehensive portfolio of PDE4 inhibitors. The company provides high-quality Rolipram to academic institutions, pharmaceutical companies, and contract research organizations worldwide, supporting drug discovery and mechanistic studies.

Research Support Initiatives:

  • Comprehensive analytical data with each batch (HPLC, NMR, MS)

  • Custom synthesis and bulk manufacturing capabilities

  • Technical support for research applications


9️⃣ 2. Focus Biomolecules

Headquarters: Plymouth Meeting, Pennsylvania, USA
Key Offering: Rolipram (PDE4 inhibitor), Biochemical tools

Focus Biomolecules specializes in providing bioactive small molecules for research purposes. Their Rolipram offerings support investigations into cAMP signaling pathways and inflammatory processes, serving the global research community with reliable, well-characterized compounds.

Research Support Initiatives:

  • Rigorous quality control standards

  • Application-specific product documentation


8️⃣ 3. PeproTech

Headquarters: Cranbury, New Jersey, USA
Key Offering: Rolipram, Cytokines, Growth factors

PeproTech, acquired by Thermo Fisher Scientific, is a recognized manufacturer of recombinant proteins and research chemicals. The company supplies Rolipram to support cellular and molecular biology research, particularly in immunology and neuroscience applications.

Research Support Initiatives:

  • GMP-like manufacturing standards for research products

  • Global distribution network ensuring prompt delivery


7️⃣ 4. R&D Systems (Bio-Techne)

Headquarters: Minneapolis, Minnesota, USA
Key Offering: Rolipram, Antibodies, Assays

R&D Systems, a Bio-Techne brand, is a premier supplier of reagents for life science research. Their Rolipram product is backed by extensive quality control and supports research in neurobiology, inflammation, and cancer biology through well-established distribution channels.

Research Support Initiatives:

  • Comprehensive technical data sheets and protocols

  • Integration with complementary research tools

Download FREE Sample Report:
Rolipram Market – View in Detailed Research Report


6️⃣ 5. Sincere Chemical

Headquarters: Shanghai, China
Key Offering: Rolipram (98%, 99% purity), Pharmaceutical intermediates

Sincere Chemical is a Chinese manufacturer and supplier of fine chemicals and pharmaceutical intermediates. The company produces Rolipram for both research and potential therapeutic development, serving global markets with competitive pricing and scalable production capabilities.

Research Support Initiatives:

  • Cost-effective manufacturing for research budgets

  • Custom synthesis services for derivative compounds


5️⃣ 6. STEMCELL Technologies

Headquarters: Vancouver, Canada
Key Offering: Rolipram, Cell culture reagents, Differentiation kits

STEMCELL Technologies develops specialized reagents and tools for cell biology research. While primarily known for cell culture products, the company supplies Rolipram as part of its portfolio of small molecules used in stem cell research, particularly in neural differentiation protocols.

Research Support Initiatives:

  • Application-specific optimization for stem cell research

  • Scientific support from field application specialists


4️⃣ 7. Toronto Research Chemicals

Headquarters: Toronto, Canada
Key Offering: High-purity Rolipram, Metabolites, Isotope-labeled compounds

Toronto Research Chemicals (TRC), a LGC company, is a leading global manufacturer of high-purity biochemicals for research. TRC offers Rolipram with comprehensive analytical characterization, supporting academic, pharmaceutical, and governmental research institutions worldwide.

Research Support Initiatives:

  • Extensive certificate of analysis with each product

  • Custom synthesis of Rolipram analogs and metabolites


3️⃣ 8. XpressBio

Headquarters: Thurmont, Maryland, USA
Key Offering: Rolipram, Life science reagents, Custom services

XpressBio provides research chemicals and biological reagents to the scientific community. The company supplies Rolipram for various research applications, focusing on quality and reliability for researchers investigating PDE4 biology and related pathways.

Research Support Initiatives:

  • Competitive pricing for academic research programs

  • Flexible packaging options from milligram to gram quantities


2️⃣ 9. Cayman Chemical

Headquarters: Ann Arbor, Michigan, USA
Key Offering: Rolipram, Biochemical assay kits, Research chemicals

Cayman Chemical is a leading supplier of biochemical tools for research, including high-quality Rolipram for studying phosphodiesterase activity. The company serves pharmaceutical, biotechnology, and academic researchers with rigorously tested compounds and comprehensive product support.

Research Support Initiatives:

  • Batch-specific quality control documentation

  • Technical support for assay development


1️⃣ 10. MedChemExpress

Headquarters: Monmouth Junction, New Jersey, USA
Key Offering: Rolipram (HY-12314), Inhibitor compounds, Reference standards

MedChemExpress (MCE) provides high-performance biochemicals for research and development. The company offers Rolipram with guaranteed purity and stability, supporting drug discovery efforts in neurological disorders, inflammatory conditions, and cancer research.

Research Support Initiatives:

  • Strict quality control with multiple analytical methods

  • Bulk quantities available for screening campaigns

Get Full Report Here:
Rolipram Market – View in Detailed Research Report


🔬 Outlook: The Future of Rolipram Research and Applications

The Rolipram market is experiencing steady growth as research into PDE4 inhibition continues to uncover new therapeutic possibilities. While primarily used as a research tool, the compound’s mechanism of action continues to inform drug development programs targeting inflammation, neurological disorders, and cancer.

📈 Key Trends Shaping the Market:

  • Increasing research into neuroinflammatory conditions and depression mechanisms

  • Growing demand for high-purity research chemicals with comprehensive documentation

  • Expansion of pharmaceutical R&D in emerging markets driving reagent demand

  • Advancements in analytical techniques ensuring product quality and reproducibility

Get Full Report Here:
Rolipram Market – View in Detailed Research Report

The companies profiled above are not only supplying critical research tools—they’re enabling the scientific discoveries that may lead to future therapies for some of medicine’s most challenging conditions.