Top 10 Companies in the 2-Methylmaleic Anhydride Industry (2025): Market Leaders Powering Global Chemical Innovation

In Business Insights
November 26, 2025

The Global 2-Methylmaleic Anhydride Market was valued at USD 62.8 Million in 2024 and is projected to reach USD 89.3 Million by 2030, growing at a Compound Annual Growth Rate (CAGR) of 6.1% during the forecast period (2024–2030). This growth is being driven by increasing demand for high-performance polymers, advancements in pharmaceutical synthesis, and the expanding applications of specialty chemicals across various industrial sectors.

As the chemical industry evolves toward more sophisticated and specialized intermediates, the focus intensifies on the key manufacturers who are driving innovation, purity standards, and application development. In this blog, we profile the Top 10 Companies in the 2-Methylmaleic Anhydride Industry—a mix of established chemical suppliers, specialty manufacturers, and research-focused entities shaping the future of this versatile chemical compound.


🔟 1. SynQuest Labs, Inc.

Headquarters: Alachua, Florida, USA
Key Offering: High-Purity 2-Methylmaleic Anhydride, Custom Synthesis

SynQuest Labs is a leading supplier of high-purity chemical reagents and catalysts, with a strong reputation for quality and reliability in the research and development sector. Their 2-Methylmaleic Anhydride is widely used in academic and industrial laboratories for synthesizing novel compounds and materials.

Innovation Initiatives:

  • Development of ultra-pure grades for sensitive pharmaceutical applications
  • Custom synthesis services for tailored molecular structures
  • Collaboration with research institutions on new application pathways

Download FREE Sample Report:
2-Methylmaleic Anhydride Market – View in Detailed Research Report


9️⃣ 2. Cepham Life Sciences, Inc

Headquarters: Owings Mills, Maryland, USA
Key Offering: Pharmaceutical-Grade 2-Methylmaleic Anhydride, Biochemical Reagents

Cepham Life Sciences specializes in providing high-quality biochemicals and pharmaceutical intermediates to the life sciences industry. Their stringent quality control processes ensure that their 2-Methylmaleic Anhydride meets the exacting standards required for drug development and biomedical research.

Innovation Initiatives:

  • Focus on cGMP-compliant manufacturing processes
  • Expansion into bio-conjugation reagent applications

8️⃣ 3. TCI (Tokyo Chemical Industry Co., Ltd.)

Headquarters: Tokyo, Japan
Key Offering: 2-Methylmaleic Anhydride, Fine Chemicals, Research Chemicals

TCI is a global leader in the manufacturing and distribution of high-purity fine chemicals. With a vast product portfolio exceeding 30,000 items, TCI’s 2-Methylmaleic Anhydride is a trusted reagent in research laboratories worldwide, known for its consistency and reliability.

Innovation Initiatives:

  • Continuous process optimization for enhanced purity levels
  • Global distribution network ensuring supply chain resilience

7️⃣ 4. Thermo Scientific Chemicals

Headquarters: Waltham, Massachusetts, USA
Key Offering: 2-Methylmaleic Anhydride, Laboratory Chemicals, Analytical Reagents

As part of Thermo Fisher Scientific, Thermo Scientific Chemicals provides a comprehensive range of high-purity chemicals for research and industrial applications. Their 2-Methylmaleic Anhydride is backed by extensive quality assurance protocols and technical support services.

Innovation Initiatives:

  • Integration with analytical instrumentation for quality verification
  • Development of application-specific chemical formulations

Download FREE Sample Report:
2-Methylmaleic Anhydride Market – View in Detailed Research Report


6️⃣ 5. Alfa Aesar

Headquarters: Haverhill, Massachusetts, USA
Key Offering: 2-Methylmaleic Anhydride, Research Chemicals, Metalorganics

Alfa Aesar, a Thermo Fisher Scientific brand, is a leading manufacturer and supplier of research chemicals, metals, and materials. Their product line includes various grades of 2-Methylmaleic Anhydride tailored for different research and industrial applications, supported by detailed technical documentation.

Innovation Initiatives:

  • Expansion of certified reference materials portfolio
  • Investment in sustainable manufacturing practices

5️⃣ 6. Merck Millipore

Headquarters: Darmstadt, Germany
Key Offering: 2-Methylmaleic Anhydride, Life Science Reagents, Lab Solutions

Merck Millipore, part of Merck KGaA, offers a comprehensive portfolio of products and services for the life science and biopharmaceutical industries. Their 2-Methylmaleic Anhydride is manufactured under strict quality controls suitable for critical research and development applications.

Innovation Initiatives:

  • Development of chromatography and purification reagents
  • Focus on biopharmaceutical processing applications

4️⃣ 7. MP Biomedicals

Headquarters: Irvine, California, USA
Key Offering: 2-Methylmaleic Anhydride, Biochemicals, Diagnostic Reagents

MP Biomedicals is a global life sciences and diagnostics company that provides high-quality biochemicals and reagents. Their expertise in manufacturing specialty chemicals makes them a reliable supplier of 2-Methylmaleic Anhydride for research and industrial applications.

Innovation Initiatives:

  • Expansion into immunoassay and molecular biology applications
  • Quality systems compliant with international standards

3️⃣ 8. Santa Cruz Biotechnology, Inc.

Headquarters: Dallas, Texas, USA
Key Offering: 2-Methylmaleic Anhydride, Research Antibodies, Biochemicals

Santa Cruz Biotechnology is primarily known for its antibodies but also offers a diverse portfolio of biochemicals for research purposes. Their 2-Methylmaleic Anhydride supports various chemical synthesis applications in academic and industrial research settings.

Innovation Initiatives:

  • Integration of chemical and biological research products
  • Support for proteomics and genomics research applications

2️⃣ 9. BASF SE

Headquarters: Ludwigshafen, Germany
Key Offering: 2-Methylmaleic Anhydride, Chemical Intermediates, Performance Chemicals

BASF is one of the world’s largest chemical producers with extensive capabilities in chemical intermediate manufacturing. While their portfolio is vast, they maintain production capabilities for specialty anhydrides including 2-Methylmaleic Anhydride for industrial applications.

Innovation Initiatives:

  • Scale-up production for commercial applications
  • Development of sustainable chemical processes

1️⃣ 10. Sigma-Aldrich (Merck KGaA)

Headquarters: St. Louis, Missouri, USA
Key Offering: 2-Methylmaleic Anhydride, Laboratory Reagents, Analytical Standards

Sigma-Aldrich, now part of Merck KGaA, is a leading life science and high-technology company. Their 2-Methylmaleic Anhydride is available in various purity grades and packaging options to meet diverse research and industrial needs, backed by comprehensive technical support.

Innovation Initiatives:

  • Development of certified reference materials
  • Expansion of high-purity chemical portfolio

Get Full Report Here:
2-Methylmaleic Anhydride Market – View in Detailed Research Report


🔬 Outlook: The Future of 2-Methylmaleic Anhydride Is Innovation-Driven

The 2-Methylmaleic Anhydride market is experiencing significant transformation. While traditional applications in polymer chemistry continue to dominate, the industry is investing heavily in new application development, purification technologies, and sustainable manufacturing processes.

📈 Key Trends Shaping the Market:

  • Growing demand for high-purity grades in pharmaceutical synthesis
  • Expansion into agrochemical and material science applications
  • Increasing research into bioconjugation and protein modification techniques
  • Strategic collaborations between chemical suppliers and end-user industries

Get Full Report Here:
2-Methylmaleic Anhydride Market – View in Detailed Research Report

The companies listed above are not only supplying essential chemical intermediates—they’re driving the innovation ecosystem that enables advancements across multiple high-technology industries.