The Global Polyhexamethylene Guanidine Hydrochloride (PHMG-HCl) Market was valued at USD 68.3 Million in 2023 and is projected to reach USD 102.5 Million by 2030, growing at a Compound Annual Growth Rate (CAGR) of 5.9% during the forecast period (2023–2030). This robust growth is primarily driven by heightened awareness of hygiene and infection control post-pandemic, increasing demand for effective water treatment solutions, and the expanding application of PHMG-HCl in the textile and pulp & paper industries.

As industries worldwide prioritize antimicrobial protection and material preservation, the role of high-efficacy biocides like PHMG-HCl has become indispensable. This blog profiles the Top 10 Companies in the Polyhexamethylene Guanidine Hydrochloride Market—a group of specialized chemical manufacturers and distributors shaping the supply chain for this critical polymer.

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Global and Regional Polyhexamethylene Guanidine HydrochlorideMarket – View in Detailed Research Report

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🔟 1. Aecochem

Headquarters: Nanjing, China
Key Offering: High-Purity PHMG-HCl, Custom Synthesis Services

Aecochem is a leading supplier of fine chemicals and pharmaceutical intermediates, including high-grade Polyhexamethylene Guanidine Hydrochloride. The company serves a global clientele with a focus on quality control and scalable production capabilities for industrial biocides.

Innovation and Market Focus:

• Specialization in high-purity (>98%) PHMG-HCl for sensitive applications

• Strong R&D focus on developing eco-friendly antimicrobial formulations

• Strategic partnerships with water treatment and coating manufacturers

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9️⃣ 2. BOC Sciences

Headquarters: Shirley, New York, USA
Key Offering: PHMG-HCl for Research, Pharmaceutical, and Industrial Use

BOC Sciences provides comprehensive chemical products and services, including Polyhexamethylene Guanidine Hydrochloride for various applications. Their strength lies in supplying high-quality compounds for research institutions and industrial customers worldwide.

Innovation and Market Focus:

• Extensive product portfolio catering to R&D and large-scale industrial needs

• Robust logistics network ensuring reliable global supply

• Technical support for formulation development

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8️⃣ 3. Chemieliva Pharmaceutical

Headquarters: Nanjing, China
Key Offering: Pharmaceutical-Grade PHMG-HCl, Custom Synthesis

Chemieliva Pharmaceutical specializes in the research, development, and production of advanced pharmaceutical intermediates and fine chemicals. The company is a significant producer of PHMG-HCl, with applications extending to antimicrobial agents and preservatives.

Innovation and Market Focus:

• GMP-compliant manufacturing processes

• Focus on pharmaceutical and high-value industrial applications

• Investment in green chemistry initiatives

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Global and Regional Polyhexamethylene Guanidine HydrochlorideMarket – View in Detailed Research Report

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7️⃣ 4. Hangzhou J&H Chemical

Headquarters: Hangzhou, Zhejiang, China
Key Offering: PHMG-HCl, Chemical Intermediates, Custom Manufacturing

Hangzhou J&H Chemical is a well-established supplier of chemical intermediates, including Polyhexamethylene Guanidine Hydrochloride. The company leverages its strong manufacturing base in China to serve both domestic and international markets efficiently.

Innovation and Market Focus:

• Competitive pricing due to integrated manufacturing

• Broad application expertise in biocides and disinfectants

• Strict quality assurance protocols

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6️⃣ 5. Hangzhou Meite Chemical

Headquarters: Hangzhou, Zhejiang, China
Key Offering: PHMG-HCl, Specialty Surfactants, Antimicrobial Agents

Hangzhou Meite Chemical specializes in the production of specialty chemicals, with a dedicated focus on antimicrobial agents like PHMG-HCl. The company has built a reputation for reliability and product consistency in the global market.

Innovation and Market Focus:

• Development of synergistic antimicrobial blends

• Focus on sustainable and low-toxicity formulations

• Expansion into emerging markets for water treatment chemicals

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5️⃣ 6. Leap Labchem

Headquarters: Changsha, Hunan, China
Key Offering: Laboratory Chemicals, PHMG-HCl for Research

Leap Labchem is a supplier focused on providing high-purity chemicals for research and development purposes. Their offering of PHMG-HCl supports academic, pharmaceutical, and industrial R&D activities globally.

Innovation and Market Focus:

• Supply of analytical-grade PHMG-HCl for research

• Support for innovation in new antimicrobial applications

• Collaboration with research institutions

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4️⃣ 7. Ningbo EST Chemical

Headquarters: Ningbo, Zhejiang, China
Key Offering: Industrial Biocides, PHMG-HCl, Chemical Intermediates

Ningbo EST Chemical is a manufacturer and exporter of chemical products, including Polyhexamethylene Guanidine Hydrochloride used in disinfection, water treatment, and material preservation. The company emphasizes cost-effective production and global distribution.

Innovation and Market Focus:

• Scalable production to meet large-volume industrial demand

• Focus on export markets, particularly in Southeast Asia and Europe

• Continuous process optimization for efficiency

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3️⃣ 8. Xiamen Hisunny Chemical

Headquarters: Xiamen, Fujian, China
Key Offering: PHMG-HCl, Fine Chemicals, Custom Synthesis

Xiamen Hisunny Chemical is engaged in the development, production, and sale of fine chemicals. The company supplies PHMG-HCl to various sectors, leveraging its technical expertise and manufacturing capabilities.

Innovation and Market Focus:

• Custom synthesis services for specific customer requirements

• Strong presence in the Asian chemical market

• Investment in R&D for novel applications of guanidine-based compounds

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Global and Regional Polyhexamethylene Guanidine HydrochlorideMarket – View in Detailed Research Report

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2️⃣ 9. IRO GROUP

Headquarters: Qingdao, Shandong, China
Key Offering: Industrial Chemicals, PHMG-HCl, Water Treatment Chemicals

IRO GROUP is a diversified chemical company with a significant focus on water treatment chemicals and industrial biocides. Their production of PHMG-HCl supports applications in cooling water systems, paper mills, and swimming pool sanitation.

Innovation and Market Focus:

• Integrated supply chain from raw materials to finished products

• Expertise in formulating biocides for complex industrial systems

• Focus on environmental regulations and compliance

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1️⃣ 10. Hunan Lijie Biochemical

Headquarters: Changsha, Hunan, China
Key Offering: High-Purity PHMG-HCl, Biochemical Products

Hunan Lijie Biochemical specializes in the production of biochemical products and fine chemicals, with a strong portfolio that includes Polyhexamethylene Guanidine Hydrochloride. The company is known for its technical expertise and commitment to quality.

Innovation and Market Focus:

• Production of high-purity PHMG-HCl for critical applications

• Strong R&D capabilities in polymer chemistry

• Strategic focus on the growing biocide market in Asia-Pacific

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Global and Regional Polyhexamethylene Guanidine HydrochlorideMarket – View in Detailed Research Report

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🌍 Outlook: The Future of PHMG-HCl Is Driven by Sustainability and Efficacy

The Polyhexamethylene Guanidine Hydrochloride market is evolving rapidly, influenced by global health trends, environmental regulations, and technological advancements. While traditional applications remain strong, the industry is increasingly focused on developing safer, more sustainable formulations and exploring new, high-value applications.

📈 Key Trends Shaping the Market:

• Growing demand for green and sustainable biocides with lower environmental impact

• Increasing regulatory scrutiny and the need for compliant formulations

• Expansion into novel applications in medical devices and functional textiles

• R&D focus on enhancing the efficacy and selectivity of PHMG-HCl based products

Get Full Report Here:
Global and Regional Polyhexamethylene Guanidine HydrochlorideMarket – View in Detailed Research Report

The companies profiled above are at the forefront of supplying a critical component for modern hygiene and material preservation—they are enabling safer environments and more durable products across multiple industries.