Top 10 Companies in the Polyhexamethylene Guanidine Hydrochloride Market (2025): Key Players in Disinfection and Biocidal Solutions

In Business Insights
November 24, 2025


The Global Polyhexamethylene Guanidine Hydrochloride (PHMG-HCl) Market was valued at US$ 95.8 Million in 2023 and is projected to reach US$ 128.4 Million by 2030, growing at a Compound Annual Growth Rate (CAGR) of 4.1% during the forecast period (2024–2030). This growth is primarily driven by increasing demand for effective and broad-spectrum disinfectants in healthcare, public sanitation, and industrial water treatment applications, alongside heightened hygiene awareness post-pandemic.

As global health and safety standards continue to evolve, the demand for reliable and potent biocidal agents has never been higher. In this blog, we profile the Top 10 Companies in the Polyhexamethylene Guanidine Hydrochloride Industry—a group of specialized chemical manufacturers and suppliers who are pivotal in providing essential disinfection solutions across various sectors.


🔟 1. Aecochem

Headquarters: Shanghai, China
Key Offering: High-purity PHMG-HCl, Custom Synthesis Services

Aecochem is a leading supplier of fine chemicals and pharmaceutical intermediates, including high-quality Polyhexamethylene Guanidine Hydrochloride. The company serves a global clientele with a focus on research institutions and industrial manufacturers requiring consistent and reliable biocidal ingredients.

Key Strengths:

  • Strong R&D capabilities for custom synthesis

  • Strict quality control ensuring high product purity

  • Global distribution network for efficient logistics

Download FREE Sample Report: Polyhexamethylene Guanidine Hydrochloride Market – View in Detailed Research Report


9️⃣ 2. BOC Sciences

Headquarters: Shirley, New York, USA
Key Offering: PHMG-HCl for Research and Development, Bulk Chemical Supply

BOC Sciences is a globally recognized supplier of chemicals for research and industrial applications. The company provides Polyhexamethylene Guanidine Hydrochloride with detailed technical data and supports various industries, including healthcare and material science.

Key Strengths:

  • Comprehensive product portfolio for diverse applications

  • Extensive technical support and documentation

  • Reliable supply chain for bulk and small-scale orders


8️⃣ 3. Hangzhou Meite Chemical

Headquarters: Hangzhou, Zhejiang, China
Key Offering: Industrial-grade and High-Purity PHMG-HCl

Hangzhou Meite Chemical specializes in the production of guanidine-based compounds. With a dedicated manufacturing facility, the company is a key producer of PHMG-HCl, catering to the water treatment and disinfectant industries, particularly in the Asia-Pacific region.

Key Strengths:

  • Vertically integrated production capabilities

  • Competitive pricing for industrial-scale buyers

  • Established presence in the Asian chemical market


7️⃣ 4. Leap Labchem

Headquarters: Mumbai, Maharashtra, India
Key Offering: Laboratory Reagents and Specialty Chemicals including PHMG-HCl

Leap Labchem is a prominent supplier of high-purity laboratory chemicals and fine ingredients. The company provides Polyhexamethylene Guanidine Hydrochloride primarily to research laboratories and quality control units in various manufacturing industries.

Key Strengths:

  • Focus on high-purity grades for analytical applications

  • Strong customer service and technical assistance

  • Growing distribution network across India and neighboring countries

Download FREE Sample Report: Polyhexamethylene Guanidine Hydrochloride Market – View in Detailed Research Report


6️⃣ 5. Ningbo EST Chemical

Headquarters: Ningbo, Zhejiang, China
Key Offering: PHMG-HCl, Textile Auxiliaries, and Biocides

Ningbo EST Chemical is a manufacturer and exporter of specialty chemicals, with a significant focus on biocides and textile chemicals. The company produces PHMG-HCl used as a preservative and disinfectant in various industrial processes.

Key Strengths:

  • Specialization in chemicals for textile and material preservation

  • Competitive manufacturing cost structure

  • Experience in international trade and export compliance


5️⃣ 6. Xiamen Hisunny Chemical

Headquarters: Xiamen, Fujian, China
Key Offering: PHMG-HCl, Pharmaceutical Intermediates, and Fine Chemicals

Xiamen Hisunny Chemical is an integrated company engaged in the development, production, and sale of fine chemicals. It supplies Polyhexamethylene Guanidine Hydrochloride to sectors requiring effective antimicrobial agents, such as coatings and personal care.

Key Strengths:

  • Diverse application knowledge across multiple industries

  • Focus on innovation and developing new chemical solutions

  • Robust quality assurance protocols


4️⃣ 7. IRO GROUP

Headquarters: Qingdao, Shandong, China
Key Offering: Industrial Biocides, including PHMG-HCl for Water Treatment

IRO GROUP is a specialist in water treatment chemicals and industrial antimicrobials. The company is a key supplier of PHMG-HCl, which is extensively used to control microbial growth in cooling towers, pulp and paper processing, and other industrial water systems.

Key Strengths:

  • Deep expertise in industrial water treatment applications

  • Customized formulations for specific industrial needs

  • Strong technical service and on-site support


3️⃣ 8. Hunan Lijie Biochemical

Headquarters: Changsha, Hunan, China
Key Offering: PHMG-HCl, Guanidine Salts, and Other Biochemicals

Hunan Lijie Biochemical is a manufacturer focused on guanidine derivatives and other biochemical products. The company has production facilities dedicated to synthesizing high-purity PHMG-HCl for domestic and international markets.

Key Strengths:

  • Specialized manufacturing of guanidine-based compounds

  • Strategic location in a major Chinese chemical industry hub

  • Commitment to expanding production capacity to meet growing demand


2️⃣ 9. Shanghai UCHEM

Headquarters: Shanghai, China
Key Offering: High-Purity PHMG-HCl for Pharmaceutical and Cosmetic Applications

Shanghai UCHEM is a supplier of fine chemicals and ingredients for the pharmaceutical, cosmetic, and personal care industries. The company provides high-grade PHMG-HCl used as a preservative in formulations where stringent purity standards are required.

Key Strengths:

  • Focus on high-value applications in pharmaceuticals and cosmetics

  • Adherence to international quality and regulatory standards

  • Strong relationships with manufacturers in regulated industries


1️⃣ 10. Wilshire Technologies

Headquarters: Princeton, New Jersey, USA
Key Offering: Specialty Chemicals and Custom Synthesis of PHMG-HCl

Wilshire Technologies is a North American supplier specializing in custom synthesis and the distribution of specialty chemicals. The company caters to clients requiring PHMG-HCl for research, development, and specialized industrial applications, offering tailored solutions and reliable supply.

Key Strengths:

  • Strategic presence in the North American market

  • Flexibility in handling custom synthesis and small-batch production

  • Expertise in navigating regulatory requirements for biocides

Get Full Report Here: Polyhexamethylene Guanidine Hydrochloride Market – View in Detailed Research Report


🌍 Outlook: The Future of PHMG-HCl is Driven by Hygiene and Safety Demands

The Polyhexamethylene Guanidine Hydrochloride market is experiencing steady growth, underpinned by its critical role as a powerful biocide. While traditional applications dominate current consumption, the industry is exploring new formulations and synergistic blends to enhance efficacy and meet evolving regulatory standards.

📈 Key Trends Shaping the Market:

  • Increasing incorporation in long-lasting disinfectant coatings for high-touch surfaces

  • Growing demand from the water treatment industry for biofilm control

  • R&D focused on improving environmental profile and biodegradability

  • Expansion of applications in agricultural chemicals and veterinary hygiene

Get Full Report Here: Polyhexamethylene Guanidine Hydrochloride Market – View in Detailed Research Report

The companies listed above are not only supplying a crucial chemical ingredient—they are enabling advanced hygiene solutions that protect public health and ensure industrial safety worldwide.