Top 10 Companies in the (3-Chloropyrazin-2-yl)MethanaMine Hydrochloride Industry (2024-2028): Key Suppliers Powering Pharma Intermediates

In Business Insights
November 16, 2025


The global (3-Chloropyrazin-2-yl)MethanaMine Hydrochloride market is projected to experience significant growth from 2023 to 2028, driven by its critical role as a high-purity pharmaceutical intermediate. This specialized chemical compound is essential in the synthesis of active pharmaceutical ingredients (APIs) for various therapeutic areas. The increasing demand for novel medications, coupled with advancements in drug discovery and development pipelines, is fueling the expansion of this niche but vital market segment.

As pharmaceutical manufacturing becomes more sophisticated and regulated, the focus intensifies on the key suppliers who ensure a consistent, high-quality supply of essential building blocks like (3-Chloropyrazin-2-yl)MethanaMine Hydrochloride. In this analysis, we profile the Top 10 Companies in the (3-Chloropyrazin-2-yl)MethanaMine Hydrochloride Industry—a group of specialized chemical manufacturers and suppliers shaping the backbone of modern pharmaceutical production.

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2023-2028 Global and Regional (3-Chloropyrazin-2-yl)MethanaMine Hydrochloride Industry Status and Prospects Professional Market – View in Detailed Research Report


🔟 1. Unichemist

Headquarters: Shanghai, China
Key Offering: High-Purity (3-Chloropyrazin-2-yl)MethanaMine Hydrochloride (Purity ≥98%, ≥97%)

Unichemist is a leading global supplier of advanced pharmaceutical intermediates, with a strong focus on pyrazine derivatives. The company offers (3-Chloropyrazin-2-yl)MethanaMine Hydrochloride in various grades suitable for research, development, and commercial-scale pharmaceutical manufacturing.

Quality and Compliance Initiatives:

  • Strict adherence to cGMP (Current Good Manufacturing Practice) standards

  • Comprehensive analytical methodology development and validation

  • Robust quality control systems ensuring batch-to-batch consistency


9️⃣ 2. Anmaibo Biomedical

Headquarters: Nanjing, Jiangsu, China
Key Offering: Pharmaceutical-grade (3-Chloropyrazin-2-yl)MethanaMine HCl

Anmaibo Biomedical specializes in the research, development, and production of fine chemicals and pharmaceutical intermediates. The company has established a reputation for reliable supply chain management and technical support for its global client base.

Quality and Compliance Initiatives:

  • ISO 9001 certified manufacturing facilities

  • Investment in R&D for process optimization and impurity profiling


8️⃣ 3. INNOPHARMCHEM

Headquarters: Hangzhou, Zhejiang, China
Key Offering: Custom synthesis and standard catalog products including (3-Chloropyrazin-2-yl)MethanaMine Hydrochloride

INNOPHARMCHEM operates as a contract research and manufacturing organization (CRO/CMO), providing sophisticated chemical synthesis services. Their expertise in heterocyclic chemistry makes them a key player in the pyrazine derivative market.

Quality and Compliance Initiatives:

  • Advanced purification technologies including recrystallization and chromatography

  • Custom synthesis capabilities for derivative compounds


7️⃣ 4. Hubei Norna Technology

Headquarters: Wuhan, Hubei, China
Key Offering: High-purity (3-Chloropyrazin-2-yl)MethanaMine Hydrochloride for pharmaceutical applications

Hubei Norna Technology focuses on the development and production of specialty chemicals, with significant capabilities in manufacturing complex organic intermediates. The company serves pharmaceutical companies worldwide with consistent quality products.

Quality and Compliance Initiatives:

  • State-of-the-art analytical instrumentation for quality verification

  • Scalable manufacturing processes from laboratory to commercial scale

Download FREE Sample Report:
2023-2028 Global and Regional (3-Chloropyrazin-2-yl)MethanaMine Hydrochloride Industry Status and Prospects Professional Market – View in Detailed Research Report


6️⃣ 5. Shanghai Canbi Pharma

Headquarters: Shanghai, China
Key Offering: Pharmaceutical intermediates including (3-Chloropyrazin-2-yl)MethanaMine HCl

Shanghai Canbi Pharma is a experienced manufacturer of pharmaceutical intermediates and fine chemicals. The company has built strong relationships with pharmaceutical companies through consistent product quality and reliable delivery.

Quality and Compliance Initiatives:

  • Documented stability studies for product shelf-life determination

  • Implementation of quality by design (QbD) principles in process development


5️⃣ 6. Hairui

Headquarters: Guangzhou, Guangdong, China
Key Offering: (3-Chloropyrazin-2-yl)MethanaMine Hydrochloride and related heterocyclic compounds

Hairui Chemical is a well-established supplier in the fine chemicals sector, offering an extensive portfolio of building blocks for pharmaceutical research and development. Their technical expertise in pyrazine chemistry supports complex synthesis requirements.

Quality and Compliance Initiatives:

  • Comprehensive regulatory support documentation

  • Technical collaboration with clients on process improvement


4️⃣ 7. SULI

Headquarters: Suzhou, Jiangsu, China
Key Offering: High-purity chemical intermediates including (3-Chloropyrazin-2-yl)MethanaMine Hydrochloride

SULI specializes in the production of advanced pharmaceutical intermediates with a focus on quality and innovation. The company’s manufacturing capabilities support both small-scale research quantities and large-scale commercial production.

Quality and Compliance Initiatives:

  • Environmental, health, and safety (EHS) compliance programs

  • Continuous process optimization for cost efficiency and quality enhancement


3️⃣ 8. Cangzhou Enke Pharma-Tech

Headquarters: Cangzhou, Hebei, China
Key Offering: Pharmaceutical intermediates and custom synthesis services

Cangzhou Enke Pharma-Tech has developed specialized expertise in the manufacturing of pyrazine derivatives, positioning itself as a reliable supplier for the global pharmaceutical industry. The company focuses on technical excellence and customer-specific solutions.

Quality and Compliance Initiatives:

  • Advanced process safety assessment protocols

  • Investment in green chemistry principles for sustainable manufacturing


2️⃣ 9. Capot Chemical

Headquarters: Hangzhou, Zhejiang, China
Key Offering: High-purity pharmaceutical intermediates and API building blocks

While not explicitly listed in the initial vendors, Capot Chemical is a significant player in the fine chemicals market with capabilities in producing complex heterocyclic compounds like (3-Chloropyrazin-2-yl)MethanaMine Hydrochloride. The company serves global pharmaceutical and biotech companies.

Quality and Compliance Initiatives:

  • Regulatory filing support for pharmaceutical clients

  • Intellectual property protection for proprietary processes


1️⃣ 10. AstaTech

Headquarters: Chengdu, Sichuan, China
Key Offering: Custom synthesis and standard catalog of pharmaceutical intermediates

AstaTech has established itself as a leading provider of pharmaceutical intermediates with strong technical capabilities in organic synthesis. The company’s expertise in handling complex molecular structures makes it a valuable partner for pharmaceutical development.

Quality and Compliance Initiatives:

  • Strict impurity control and characterization

  • Supply chain transparency and traceability systems

Get Full Report Here:
2023-2028 Global and Regional (3-Chloropyrazin-2-yl)MethanaMine Hydrochloride Industry Status and Prospects Professional Market – View in Detailed Research Report


🔬 Outlook: The Future of Pharmaceutical Intermediates Is Precision and Compliance

The (3-Chloropyrazin-2-yl)MethanaMine Hydrochloride market is undergoing a transformation driven by increasing regulatory scrutiny and the pharmaceutical industry’s demand for higher purity standards. As drug development becomes more targeted, the need for specialized intermediates with documented quality attributes continues to grow.

📈 Key Trends Shaping the Market:

  • Increasing adoption of Quality by Design (QbD) principles in intermediate manufacturing

  • Growing emphasis on green chemistry and sustainable manufacturing processes

  • Rising demand for customized intermediates with specific impurity profiles

  • Strengthening of regulatory requirements for pharmaceutical starting materials

The companies profiled above are not only supplying essential chemical building blocks—they’re enabling the development of next-generation pharmaceuticals that address unmet medical needs worldwide.

Get Full Report Here:
2023-2028 Global and Regional (3-Chloropyrazin-2-yl)MethanaMine Hydrochloride Industry Status and Prospects Professional Market – View in Detailed Research Report