Top 10 Companies in the Dicyclohexylcarbodiimide Market (2025): Market Leaders Driving Global Chemical Synthesis

In Business Insights
November 09, 2025


The Global Dicyclohexylcarbodiimide (DCC) Market was valued at USD 185.7 Million in 2024 and is projected to reach USD 265.3 Million by 2029, growing at a Compound Annual Growth Rate (CAGR) of 5.75% during the forecast period (2024–2029). This consistent growth is primarily driven by the expanding pharmaceutical industry, rising demand for peptide synthesis, and the compound’s critical role as a coupling agent in organic chemistry and polymer production.

As chemical manufacturing evolves toward more efficient and specialized processes, the focus shifts to the key producers who ensure the supply, quality, and innovation of essential reagents like DCC. In this analysis, we profile the Top 10 Companies in the Dicyclohexylcarbodiimide Industry—a group of established chemical giants and specialized manufacturers shaping the backbone of modern synthetic chemistry.


🔟 1. Toyobo Co., Ltd.

Headquarters: Osaka, Japan
Key Offering: High-Purity DCC, Specialty Chemicals, Functional Materials

Toyobo is a leading Japanese chemical company with a significant presence in the high-performance chemicals sector. Its production of high-purity Dicyclohexylcarbodiimide is critical for pharmaceutical intermediates and advanced material synthesis, supported by robust R&D capabilities.

Strategic Initiatives & Financial Highlights (FY2023-24):

  • Revenue (Q3 FY23-24): ¥307,323 Million; Full-year forecast: ¥410,000 Million

  • Operating Profit (Q3 FY23-24): ¥4,992 Million; Full-year forecast: ¥8,000 Million

  • Strong growth in Environmental and Functional Materials segment

  • Launched joint venture ‘Toyobo MC Corporation’ in April 2023 to enhance functional materials business

Download FREE Sample Report: Dicyclohexylcarbodiimide Global Market – View in Detailed Research Report


9️⃣ 2. Kaneka Corporation

Headquarters: Tokyo, Japan
Key Offering: DCC, Fine Chemicals, Advanced Polymers

Kaneka is a major global chemical company with a diversified portfolio. Its functional chemicals division produces DCC, serving the pharmaceutical and biotechnology sectors with high-quality reagents essential for peptide coupling and other dehydration reactions.

Strategic Initiatives & Financial Highlights (FY2023-24):

  • Revenue (Q3 FY23-24): ¥766,000 Million; Full-year forecast: ¥1,024,600 Million

  • Operating Profit (Q3 FY23-24): ¥21,611 Million; Full-year forecast: ¥32,000 Million

  • Material Solutions Unit revenue (Q3 FY23-24): ¥237,919 Million

  • Focus on high-value-added products in life sciences and electronics


8️⃣ 3. Jincheng Pharmaceutical Co., Ltd.

Headquarters: Taizhou, Zhejiang, China
Key Offering: DCC, Pharmaceutical Intermediates, APIs

Jincheng Pharmaceutical is a key Chinese manufacturer of pharmaceutical chemicals and intermediates. The company is a significant supplier of DCC within Asia, leveraging its integrated production capabilities to serve both domestic and international markets.

Strategic Initiatives & Financial Highlights:

  • Revenue: CNY 3,538.31 Million

  • Net Income: CNY 174.71 Million

  • Strategic focus on expanding its portfolio of high-purity chemical reagents

  • Strengthening position in the global pharmaceutical supply chain


7️⃣ 4. Tianyu Pharmaceutical Co., Ltd.

Headquarters: Shandong, China
Key Offering: DCC, Chemical Reagents, Custom Synthesis

Tianyu Pharmaceutical is a prominent Chinese enterprise engaged in the research, development, and production of pharmaceutical intermediates and fine chemicals, including DCC.

Strategic Initiatives & Financial Highlights (FY2022):

  • Revenue: CNY 2,649 Million (4.95% increase from previous year)

  • Net Income: CNY (119) Million (challenging year with a net loss)

  • EBITDA: CNY 176 Million

  • Ongoing R&D investments to improve process efficiency and product quality

Download FREE Sample Report: Dicyclohexylcarbodiimide Global Market – View in Detailed Research Report


6️⃣ 5. Zibo Guansheng Chemical Co., Ltd.

Headquarters: Zibo, Shandong, China
Key Offering: DCC, Fine Chemicals

Zibo Guansheng is a specialized chemical manufacturer in China, recognized as a leading producer of Dicyclohexylcarbodiimide. The company focuses on the production and supply of high-quality reagents for the chemical industry.

Strategic Initiatives:

  • Primary focus on DCC manufacturing with established production capacity

  • Private entity with a strong domestic market presence

  • Commitment to maintaining competitive pricing and reliable supply chains


5️⃣ 6. Zhanhua Jiashi Chemical Co., Ltd.

Headquarters: Binzhou, Shandong, China
Key Offering: DCC, Chemical Intermediates

Zhanhua Jiashi is another significant Chinese manufacturer in the fine chemicals space, contributing to the global supply of DCC. As a private company, it operates with a focus on efficiency and market responsiveness.

Strategic Initiatives:

  • Specialized production of chemical intermediates

  • Private entity, focusing on agile operations and customer-specific solutions

  • Active participant in the regional chemical manufacturing ecosystem


4️⃣ 7. Sigma-Aldrich (Merck KGaA)

Headquarters: Darmstadt, Germany
Key Offering: High-Purity DCC, Laboratory Reagents, Life Science Products

As part of the global Merck KGaA group, Sigma-Aldrich is a premier supplier of laboratory reagents and fine chemicals for research and development. The company offers high-purity DCC, serving academic institutions, pharmaceutical R&D, and biotech companies worldwide.

Strategic Initiatives:

  • Extensive global distribution network for research chemicals

  • Focus on ultra-high purity grades for critical research applications

  • Investment in digital platforms for seamless procurement and supply chain transparency


3️⃣ 8. TCI Chemicals (Tokyo Chemical Industry Co., Ltd.)

Headquarters: Tokyo, Japan
Key Offering: DCC, Organic Reagents, Specialty Chemicals

TCI is a leading global manufacturer and supplier of high-quality organic laboratory chemicals. The company provides DCC of various grades, catering to the stringent requirements of synthetic chemistry research and development.

Strategic Initiatives:

  • Reputation for high-quality and reliable organic reagents

  • Strong international sales presence, particularly in North America, Europe, and Asia

  • Continuous expansion of its chemical catalog to support advanced research


2️⃣ 9. Alfa Aesar (Thermo Fisher Scientific)

Headquarters: Heysham, Lancashire, UK
Key Offering: DCC, Research Chemicals, Materials Science Products

Alfa Aesar, a Thermo Fisher Scientific company, is a key supplier of research chemicals, metals, and materials. It offers DCC as part of its comprehensive portfolio of reagents for chemical synthesis and material science.

Strategic Initiatives:

  • Integration within Thermo Fisher’s vast global distribution and logistics network

  • Focus on providing documented quality and consistency for research and production

  • Investment in sustainable and safe chemical handling solutions


1️⃣ 10. Spectrum Chemical Mfg. Corp.

Headquarters: New Brunswick, New Jersey, USA
Key Offering: DCC, USP/NF/FCC Grade Chemicals, GMP Services

Spectrum Chemical is a leading supplier of fine chemicals and laboratory products with a strong focus on quality and regulatory compliance. The company provides DCC suitable for various applications, including pharmaceutical development under GMP guidelines.

Strategic Initiatives:

  • Provision of high-purity chemicals with extensive documentation

  • Strong foothold in the North American pharmaceutical and biopharma sectors

  • Emphasis on quality assurance and regulatory support services

Get Full Report Here: Dicyclohexylcarbodiimide Global Market – View in Detailed Research Report


🧪 Outlook: The Future of Dicyclohexylcarbodiimide Is Driven by Innovation and Specialization

The Dicyclohexylcarbodiimide market is experiencing steady evolution. While its core application in peptide synthesis remains a dominant driver, the industry is exploring process optimizations, alternative reagents, and applications in advanced material science.

📈 Key Trends Shaping the Market:

  • Growing demand for pharmaceuticals and biologics, fueling need for peptide synthesis reagents

  • Research into greener and more sustainable coupling agents alongside established DCC processes

  • Increasing capacity and technological advancements from Chinese manufacturers

  • Expansion of DCC applications in polymer chemistry and material science

Get Full Report Here: Dicyclohexylcarbodiimide Global Market – View in Detailed Research Report

The companies listed above are not only supplying a critical chemical reagent—they are enabling innovation across pharmaceuticals and advanced materials worldwide.