Top 10 Companies in the 4-Phenylbutyric Acid Industry (2025): Market Leaders Driving Pharmaceutical Innovation

In Business Insights
October 24, 2025


The Global 4-Phenylbutyric Acid Market was valued at USD 122.8 Million in 2023 and is projected to reach USD 168.5 Million by 2030, growing at a Compound Annual Growth Rate (CAGR) of 4.7% during the forecast period (2024–2030). This growth is being driven by increasing applications in pharmaceutical intermediates, rising demand for high-purity chemical compounds, and the expanding therapeutic applications across neurology, oncology, and metabolic disorders.

As the pharmaceutical and chemical industries continue to evolve with precision medicine and advanced manufacturing, the spotlight is on the key manufacturers who are driving innovation, quality control, and supply chain reliability. In this blog, we profile the Top 10 Companies in the 4-Phenylbutyric Acid Industry—a mix of established chemical manufacturers, pharmaceutical intermediates producers, and specialty chemical innovators shaping the future of this critical compound.


🔟 1. Zhejiang Shaxing Technology Co., Ltd.

Headquarters: Shaoxing, Zhejiang, China
Key Offering: 98% Purity 4-Phenylbutyric Acid, 99% Purity Pharmaceutical Grade

Zhejiang Shaxing Technology is one of China’s leading producers of 4-Phenylbutyric Acid, specializing in high-purity grades for pharmaceutical applications. Their manufacturing facilities adhere to strict quality control standards, serving both domestic and international markets with consistent product quality and reliable supply chains.

Manufacturing Capabilities:

  • Advanced purification technologies for high-purity grades

  • Strategic partnerships with global pharmaceutical companies

  • Continuous expansion of production capacity to meet growing market demand

Download FREE Sample Report: Global 4-Phenylbutyric Acid Market – View in Detailed Research Report


9️⃣ 2. Seqens

Headquarters: Paris, France
Key Offering: Pharmaceutical Grade 4-PBA, Ultra-Pure Chemical Intermediates

Seqens is a global leader in pharmaceutical solutions and specialty chemicals, offering high-quality 4-Phenylbutyric Acid through their extensive chemical synthesis expertise. The company operates multiple GMP-certified facilities across Europe and North America, ensuring consistent quality for critical pharmaceutical applications.

Manufacturing Capabilities:

  • Integrated manufacturing from chemical synthesis to purification

  • Custom synthesis capabilities for specialized pharmaceutical requirements


8️⃣ 3. AlzChem Group AG

Headquarters: Trostberg, Germany
Key Offering: Fine Chemicals, Pharmaceutical Intermediates, 4-PBA

AlzChem is a globally active specialty chemicals company with strong expertise in fine chemicals and pharmaceutical raw materials. Their production capabilities include both standard and custom synthesis of 4-Phenylbutyric Acid with rigorous quality assurance.

Manufacturing Capabilities:

  • Manufacturing plants in Germany and China

  • Focus on neurodegenerative and metabolic disorder applications


7️⃣ 4. Tokyo Chemical Industry Co., Ltd.

Headquarters: Tokyo, Japan
Key Offering: Research Grade 4-PBA, Laboratory Chemicals

Tokyo Chemical Industry (TCI) is a leading global manufacturer of laboratory chemicals and fine chemicals, including high-purity 4-Phenylbutyric Acid. TCI serves pharmaceutical companies, research institutions, and academic laboratories worldwide with high-purity chemical compounds.

Manufacturing Capabilities:

  • Extensive portfolio of specialty chemicals for research and development

  • Advanced analytical laboratories for quality verification

Download FREE Sample Report: Global 4-Phenylbutyric Acid Market – View in Detailed Research Report


6️⃣ 5. Merck KGaA

Headquarters: Darmstadt, Germany
Key Offering: Life Science Reagents, Pharmaceutical Intermediates

Merck KGaA, through its Life Science business, offers high-purity chemicals including 4-Phenylbutyric Acid for research and pharmaceutical applications.

Manufacturing Capabilities:

  • Manufacturing capabilities for pharmaceutical-grade compounds

  • Global distribution network serving pharmaceutical manufacturers and research institutions


5️⃣ 6. Spectrum Chemical Mfg. Corp.

Headquarters: Gardena, California, USA
Key Offering: GMP-grade Chemicals, Pharmaceutical Raw Materials

Spectrum Chemical is a leading manufacturer and worldwide supplier of fine chemicals and laboratory products, including 4-Phenylbutyric Acid. The company provides comprehensive quality documentation and regulatory support for pharmaceutical customers.

Manufacturing Capabilities:

  • Multiple manufacturing facilities with regulatory compliance

  • Focus on quality assurance and batch-to-batch consistency for pharmaceutical applications.


    4️⃣ 7. Hefei TNJ Chemical Industry Co., Ltd.

    Headquarters: Hefei, Anhui, China
    Key Offering: Industrial Grade 4-PBA, Chemical Intermediates

    Hefei TNJ Chemical is a professional manufacturer and supplier of pharmaceutical intermediates and fine chemicals, supplying 4-Phenylbutyric Acid to global customers across multiple industries.

    Manufacturing Capabilities:

    • Diversified chemical manufacturing capabilities

    • Focus on cost-effective production while maintaining quality standards


    3️⃣ 8. Sisco Research Laboratories Pvt. Ltd.

    Headquarters: Mumbai, Maharashtra, India
    Key Offering: Fine Chemicals, Pharmaceutical Raw Materials

    As a prominent chemical manufacturer, Sisco Research Laboratories produces high-purity 4-Phenylbutyric Acid, leveraging India’s growing chemical manufacturing infrastructure.

    Manufacturing Capabilities:

    • Strong presence in pharmaceutical intermediates market

    • Growing export capabilities to emerging markets


    2️⃣ 9. Carbosynth Ltd.

    Headquarters: Berkshire, United Kingdom
    Key Offering: Research Chemicals, Pharmaceutical Intermediates, 4-PBA

    Carbosynth is a leading supplier of chemical and biochemical products, including 4-Phenylbutyric Acid in various purity grades for different applications.

    Manufacturing Capabilities:

    • Specialized in custom synthesis and contract manufacturing

    • Extensive network serving academic and industrial research sectors


    1️⃣ 10. Santa Cruz Biotechnology, Inc.

    Headquarters: Dallas, Texas, USA
    Key Offering: Biochemicals, Research Grade Chemicals

    Santa Cruz Biotechnology is a leader in the development and manufacturing of biochemicals for research purposes, offering 4-Phenylbutyric Acid among its extensive product portfolio for life science research applications.

    Manufacturing Capabilities:

    • Focus on research and development of novel chemical compounds

    • Strong presence in North American and European research markets

    Get Full Report Here: Global 4-Phenylbutyric Acid Market – View in Detailed Research Report


    🌍 Outlook: The Future of 4-Phenylbutyric Acid is Pharmaceutical-Focused and Quality-Driven

    The 4-Phenylbutyric Acid market is undergoing a strategic transformation. While traditional applications continue to drive volume, the industry is increasingly focusing on high-purity grades, regulatory compliance, and specialized applications in precision medicine.

    📈 Key Trends Shaping the Market:

    • Expanding therapeutic applications in neurology and metabolic disorders

    • Growing demand for pharmaceutical intermediates in emerging markets

    • Increasing regulatory requirements for chemical purity and documentation

    • Emphasis on GMP-compliant manufacturing for pharmaceutical applications

    Get Full Report Here: Global 4-Phenylbutyric Acid Market – View in Detailed Research Report

    The companies listed above are not only supplying critical chemical compounds—they’re shaping the pharmaceutical innovation landscape.

    Read Full Report: Global 4-Phenylbutyric Acid Market – View in Detailed Research Report