The Global Chloroform (CAS 67-66-3) Market was valued at USD 320.5 Million in 2024 and is projected to reach USD 465.9 Million by 2032, growing at a Compound Annual Growth Rate (CAGR) of 4.6% during the forecast period (2024–2032). This growth is being driven by steady demand from the pharmaceutical sector for API synthesis, expanding chemical manufacturing in Asia-Pacific, and rising applications in dyes, polymers, and refrigerant production.

As the chemical industry advances toward sustainable practices, regulatory compliance, and innovative solvent solutions, the spotlight is on the key producers who are driving efficiency, safety, and environmental responsibility. In this blog, we profile the Top 10 Companies in the Global Chloroform (CAS 67-66-3) Market—a mix of multinational chemical giants, specialized manufacturers, and regional leaders shaping the future of chloroform production and applications.

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🔟 1. Dow Chemical Company

Headquarters: Midland, Michigan, USA
Key Offering: Industrial Grade and Reagent Grade Chloroform

Dow Chemical Company is a global leader in chloromethane production, supplying high-quality chloroform for pharmaceutical synthesis, chemical intermediates, and solvent applications worldwide. Their integrated manufacturing processes ensure reliable supply to industries ranging from pharmaceuticals to dyes, with a focus on high-purity reagent-grade products for sensitive API extraction and purification.

Innovation Initiatives:

• Investments in sustainable chlorination technologies to reduce emissions
• Partnerships with pharmaceutical firms for customized high-purity grades
• Commitment to compliance with global environmental standards like REACH and EPA guidelines

Download FREE Sample Report: Global Chloroform (CAS 67-66-3) Market – View in Detailed Research Report

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9️⃣ 2. BASF SE

Headquarters: Ludwigshafen, Germany
Key Offering: Industrial Grade Chloroform, Reagent Grade for Labs

BASF SE operates extensive chemical production facilities, providing chloroform as a versatile solvent and intermediate for HCFC and PTMEG manufacturing. The company serves diverse sectors including textiles, refrigerants, and pharmaceuticals, emphasizing eco-friendly production methods to meet European sustainability targets.

Innovation Initiatives:

• Development of low-emission production processes for chlorinated solvents
• Collaborations with dye manufacturers to optimize chloroform usage in pigment synthesis

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8️⃣ 3. Solvay S.A.

Headquarters: Brussels, Belgium
Key Offering: High-Purity Reagent Grade, Industrial Grade Chloroform

Solvay S.A. is a prominent supplier of specialty chemicals, offering chloroform for pharmaceutical applications and chemical synthesis. Their focus on innovation supports the growing demand for high-purity grades in drug formulation and extraction processes, while navigating regulatory challenges in volatile organic compounds.

Innovation Initiatives:

• Targets for reducing chloroform-related emissions by 20% through advanced treatment systems
• Supply partnerships with global chemical and pharma industries for sustainable sourcing

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7️⃣ 4. Ineos Group Limited

Headquarters: London, United Kingdom
Key Offering: Industrial Grade Chloroform for Chemical Processing

Ineos Group Limited excels in basic and intermediate chemicals, producing chloroform primarily for use in refrigerant intermediates and polymer manufacturing. The company has a strong presence in Europe and Asia, supporting the chemical industry’s rebound with reliable, cost-effective supply chains.

Innovation Initiatives:

• Goal to integrate 15% more efficient feedstock utilization by 2030
• R&D into alternative synthesis routes to minimize environmental impact

Download FREE Sample Report: Global Chloroform (CAS 67-66-3) Market – View in Detailed Research Report

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6️⃣ 5. Shin-Etsu Chemical Co., Ltd.

Headquarters: Tokyo, Japan
Key Offering: Reagent Grade and Industrial Grade Chloroform

Shin-Etsu Chemical Co., Ltd. is a key player in Asia’s chemical sector, supplying chloroform for high-tech applications in electronics, pharmaceuticals, and dyes. Their advanced facilities ensure high-purity products compatible with precision manufacturing needs.

Innovation Initiatives:

• Offers certified low-toxicity grades at major industrial hubs
• Aims for net-zero operations in chemical production by 2050

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5️⃣ 6. Akzo Nobel N.V.

Headquarters: Amsterdam, Netherlands
Key Offering: Industrial Grade Chloroform for Coatings and Dyes

Akzo Nobel N.V. provides chloroform as part of its broad portfolio in paints, coatings, and specialty chemicals, focusing on solvent applications in the dyes and pigments sector. The company supports global trade in colored products with efficient, compliant production.

Innovation Initiatives:

• Current output enhancements for over 500,000 tons/year in related intermediates
• Target: Expand sustainable solvent lines by 2027

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4️⃣ 7. Tokuyama Corporation

Headquarters: Tokyo, Japan
Key Offering: High-Purity Chloroform for Pharmaceuticals

Tokuyama Corporation is renowned for its chloroform production tailored to pharmaceutical and semiconductor industries, supplying reagent-grade products that meet stringent purity requirements. Their expansions in 2023 underscore confidence in ongoing demand from API synthesis.

Innovation Initiatives:

• Indigenous research into bio-compatible chloroform derivatives
• Collaborations to scale production for emerging markets

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3️⃣ 8. Arihant Chemicals

Headquarters: Mumbai, India
Key Offering: Industrial Grade Chloroform for Dyes and Chemicals

Arihant Chemicals serves the South Asian market with affordable chloroform for textile dyes and chemical processing, playing a crucial role in India’s growing manufacturing sector. They focus on local supply to support export-oriented industries.

Innovation Initiatives:

• Adaptations to local environmental regulations for safer handling
• R&D programs for synthetic alternatives under innovation grants

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2️⃣ 9. Productos Aditivos de Venezuela

Headquarters: Caracas, Venezuela
Key Offering: Industrial Grade Chloroform for Regional Chemicals

Productos Aditivos de Venezuela contributes to Latin America’s chemical landscape by producing chloroform for pesticide and polymer applications, despite regional challenges. Their operations support local industries in extraction and synthesis processes.

Innovation Initiatives:

• Production aims of 100,000 tons/year through facility upgrades
• Supply chain expansions in South America

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1️⃣ 10. Solvay S.A.

Headquarters: Brussels, Belgium (Global Operations)
Key Offering: Comprehensive Chloroform Solutions, Including Logistics

Solvay S.A. leads in global distribution of chloroform, supporting over 500 industrial clients with end-to-end solutions for pharmaceutical, chemical, and dye sectors. They excel in logistics and compliance services, ensuring seamless supply amid regulatory shifts.

Innovation Initiatives:

• Full-spectrum solutions for reagent and industrial needs
• Partnerships with producers for enhanced purity and distribution

Read Full Report: Global Chloroform (CAS 67-66-3) Market – View in Detailed Research Report

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🌍 Outlook: The Future of the Chloroform Market Is Sustainable and Innovative

The chloroform market is undergoing a significant transformation. While industrial-grade products continue to lead in volume for chemical processing, the sector is channeling substantial investments into high-purity alternatives, green synthesis technologies, and compliance with international protocols like the Montreal Protocol.

📈 Key Trends Shaping the Market:

• Rapid capacity expansions in Asia-Pacific, Europe, and North America for reagent-grade production
• Regulatory mandates for reducing HCFC usage and promoting safer solvents by 2030
• Digitalization of supply chains and real-time emissions monitoring
• Industry alliances for R&D in bio-based and low-toxicity chemical pathways

Read Full Report: Global Chloroform (CAS 67-66-3) Market – View in Detailed Research Report

The companies listed above are not only supplying essential solvents globally—they’re leading the sustainable evolution of the chemical industry.