The Global 17α-Hydroxyprogesterone (17α-OHP) Market was valued at USD 180 Million in 2022 and is projected to reach USD 280 Million by 2029, growing at a Compound Annual Growth Rate (CAGR) of 6.5% during the forecast period (2022–2029). This growth is being driven by rising demand for hormone replacement therapies, increased screening for congenital adrenal hyperplasia, and expanding applications in synthesizing progesterone, megestrol, and hydrocortisone acetate across pharmaceutical and diagnostic sectors.

As the pharmaceutical landscape evolves with a focus on endocrine disorders and steroid hormone treatments, the spotlight is on the leading manufacturers advancing synthesis techniques, ensuring high-purity standards, and meeting global regulatory demands. In this blog, we profile the Top 10 Companies in the 17α-Hydroxyprogesterone (17α-OHP) Market—a blend of biotechnology firms, pharmaceutical specialists, and API producers shaping the future of hormone-based therapeutics.

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🔟 1. Shandong Sito Bio-technology

Headquarters: Jinan, Shandong Province, China
Key Offering: High-purity 17α-OHP API, pharmaceutical intermediates for hormone synthesis

Shandong Sito Bio-technology stands as a prominent player in the production of steroid hormones, with a strong emphasis on 17α-hydroxyprogesterone for medical applications. The company supplies high-quality intermediates to global pharmaceutical firms, supporting treatments for preterm labor prevention and adrenal disorders.

Key Developments:

• Expanded GMP-certified facilities for API output
• Partnerships with international pharma companies for custom synthesis
• Investments in R&D for greener synthesis methods

Download FREE Sample Report: 17α-Hydroxyprogesterone (17α-OHP) Market – View in Detailed Research Report

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9️⃣ 2. Shandong Xinhua Pharmaceutical

Headquarters: Zibo, Shandong Province, China
Key Offering: 17α-OHP with 95%+ purity, intermediates for progesterone and corticosteroids

Shandong Xinhua Pharmaceutical has established itself as a key supplier in the steroid API market, producing 17α-OHP that meets international pharmacopeia standards. Their products support synthesis of progestins and anti-inflammatory drugs for reproductive health and endocrine therapies.

Key Developments:

• Certification under EU GMP for export markets
• Collaboration with diagnostic firms for 17α-OHP-based assays

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8️⃣ 3. Jiangsu Jiaerke Pharmaceuticals

Headquarters: Nanjing, Jiangsu Province, China
Key Offering: Pharmaceutical-grade 17α-OHP, custom steroid intermediates

Jiangsu Jiaerke Pharmaceuticals excels in fine chemicals, using 17α-hydroxyprogesterone for hormonal deficiency medications. Their capabilities serve bulk API supply to pharmaceutical giants and research institutions with improved yield processes.

Key Developments:

• Targets for 95% purity segment growth to meet pharma needs
• Supply agreements with U.S. and European distributors

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7️⃣ 4. Steraloids Inc.

Headquarters: Newport, Rhode Island, USA
Key Offering: Research-grade 17α-OHP, high-purity standards for lab use

Steraloids Inc. specializes in steroid compounds like 17α-OHP for academic and pharmaceutical research. Their U.S.-based products support endocrinology advancements as biomarkers and precursors with FDA compliance.

Key Developments:

• Goal to increase production capacity for diagnostic reagents
• Inauguration of new lab facilities in the U.S.

Download FREE Sample Report: 17α-Hydroxyprogesterone (17α-OHP) Market – View in Detailed Research Report

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6️⃣ 5. Tokyo Chemical Industry Co., Ltd. (TCI)

Headquarters: Tokyo, Japan
Key Offering: 17α-OHP for research and industrial applications, various purity grades

Tokyo Chemical Industry (TCI) leads in organic chemicals, supplying 17α-hydroxyprogesterone to labs and developers. Their network aids hormone synthesis like megestrol with sustainable production techniques.

Key Developments:

• Offers 95%+ purity products for quick delivery
• Aims for net-zero operations in chemical synthesis

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5️⃣ 6. Merck KGaA (Sigma-Aldrich)

Headquarters: Darmstadt, Germany
Key Offering: Analytical standards of 17α-OHP, API for pharmaceutical use

Merck KGaA via Sigma-Aldrich offers 17α-OHP for research and production in diagnostics and progesterone manufacturing. Their global R&D ensures consistency with pharmacopeial compliance.

Key Developments:

• Current output exceeding industry averages for high-purity segments
• Target to double capacity for steroid APIs by 2026

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4️⃣ 7. Cayman Chemical Company

Headquarters: Ann Arbor, Michigan, USA
Key Offering: Bioactive 17α-OHP compounds, reference standards

Cayman Chemical provides 17α-hydroxyprogesterone as reference materials for endocrine research and trials. Their focus on purity supports reproductive medicine and personalized therapies.

Key Developments:

• Limited but focused involvement in API scale-up
• R&D programs for synthetic steroid variants

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3️⃣ 8. Hebei Yanxi Chemical Co., Ltd.

Headquarters: Shijiazhuang, Hebei Province, China
Key Offering: Bulk 17α-OHP intermediates, pharmaceutical raw materials

Hebei Yanxi Chemical contributes to chemical exports, supplying 17α-OHP for progesterone and corticosteroid production. Their cost-effective processes attract emerging markets with sustainability focus.

Key Developments:

• Indigenous research into bio-based synthesis
• Collaborations to enhance purity for export standards

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2️⃣ 9. Wuhan Senwayer Century Chemical Co., Ltd.

Headquarters: Wuhan, Hubei Province, China
Key Offering: High-purity 17α-OHP, custom hormone intermediates

Wuhan Senwayer Century Chemical supports API chains with 17α-hydroxyprogesterone for oncology and endocrinology. Their expansions improve purity amid regulatory demands.

Key Developments:

• Aims to produce expanded volumes for new applications
• Ongoing supply chain enhancements for international markets

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1️⃣ 10. Hangzhou Dayangchem Co., Ltd.

Headquarters: Hangzhou, Zhejiang Province, China
Key Offering: 17α-OHP API and distribution, logistics for steroid chemicals

Hangzhou Dayangchem distributes fine chemicals including 17α-OHP to pharmaceutical clients. Their logistics ensure reliable supply for endocrine disorder treatments.

Key Developments:

• Comprehensive solutions for API integration in formulations
• Partnerships with key producers for market expansion

Get Full Report Here: 17α-Hydroxyprogesterone (17α-OHP) Market – View in Detailed Research Report

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🌍 Outlook: The Future of the 17α-Hydroxyprogesterone (17α-OHP) Market Is Innovative and Accessible

The 17α-hydroxyprogesterone market is undergoing significant transformation, with traditional synthesis methods prevailing while substantial investments flow into biotechnological processes, purity enhancements, and distribution networks to meet pharmaceutical demands. This niche segment benefits from trends in personalized medicine and diagnostics, where the 95% purity category grows due to regulations; Asia leads production as North America and Europe drive clinical demand, though challenges like volatility require diversified chains.

📈 Key Trends Shaping the Market:

• Rapid capacity buildup in Asia, North America, and Europe
• Regulatory mandates for higher purity in APIs by 2029
• Digital tracking for supply chains and quality assurance
• Strategic alliances between manufacturers and pharma firms for therapy development

Get Full Report Here: 17α-Hydroxyprogesterone (17α-OHP) Market – View in Detailed Research Report

Download FREE Sample Report: 17α-Hydroxyprogesterone (17α-OHP) Market – View in Detailed Research Report

The companies profiled here are not only supplying critical intermediates—they’re propelling the evolution of endocrine healthcare through precision, innovation, and global accessibility.