The Global Guanidine Hydrochloride Market was valued at USD 125.7 Million in 2023 and is projected to reach USD 182.4 Million by 2030, growing at a Compound Annual Growth Rate (CAGR) of 5.2% during the forecast period (2023-2030). This growth is being driven by expanding pharmaceutical applications, increasing agrochemical demand, and specialized chemical synthesis where guanidine hydrochloride serves as a critical denaturing agent and protein solvent.
As biopharmaceutical production expands and industrial chemical standards tighten, supply chain attention turns to manufacturers ensuring purity, regulatory compliance, and bulk availability. This report profiles the Top 10 Guanidine Hydrochloride Producers Worldwide—specialty chemical firms and diversified manufacturers maintaining this niche but vital chemical supply.
🔟 1. AlzChem Group AG
Headquarters: Trostberg, Germany
Key Offering: Pharma & Technical Grade Guanidine HCl
The European chemical leader dominates high-purity guanidine hydrochloride production, serving major pharmaceutical clients through rigorous quality systems. Their integrated manufacturing covers cyanamide derivatives through final product packaging.
Technical Capabilities:
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Dedicated GMP production lines (>99.7% purity)
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REACH/CEP certified facilities
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Pharma-grade stability testing protocols
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9️⃣ 2. Hangzhou Xiangshun Chemical Co.
Headquarters: Hangzhou, China
Key Offering: Industrial-scale production
This Chinese manufacturer supplies bulk guanidine hydrochloride primarily to domestic agrochemical and textile dye markets, with growing Asia-Pacific exports. Their cost-efficient operations benefit from proximity to raw material sources.
Production Advantages:
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8,500+ metric tons annual capacity
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Streamlined logistics to chemical industry hubs
8️⃣ 3. Tangshan Sanding Chemical Technology
Headquarters: Tangshan, China
Key Offering: Custom particle size distributions
Specializing in crystallization technologies, Tangshan Sanding produces guanidine hydrochloride with tailored physical properties for pharmaceutical formulation needs—from fine powders to granular forms.
Technical Expertise:
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Patent-protected purification methods
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Particle engineering for solubility optimization
7️⃣ 4. Vihita Chemicals
Headquarters: Mumbai, India
Key Offering: Cost-competitive industrial quantities
A leading Indian supplier, Vihita serves growing pesticide and textile chemical demand across South Asia and Africa. Their competitive pricing stems from optimized feedstock procurement and energy-efficient processes.
Regional Position:
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Primary supplier to Indian agrochemical formulators
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Expanding Middle East distribution network
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6️⃣ 5. Jinhua Qianjiang Fine Chemical
Headquarters: Zhejiang, China
Key Offering: High-purity pharma intermediates
This Chinese fine chemicals specialist meets stringent pharmacopeial standards for biopharmaceutical applications. Their quality control systems ensure batch-to-batch consistency for critical drug formulation uses.
Quality Systems:
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ISO 9001 certified manufacturing
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Validated stability and impurity profiling
5️⃣ 6. SANWA Chemical Industry Co.
Headquarters: Tokyo, Japan
Key Offering: Ultra-high purity research grades
The Japanese precision chemical producer supplies laboratories and electronics manufacturers with 99.9%+ pure guanidine hydrochloride, with stricter heavy metal control than standard industrial grades.
Technical Specifications:
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Sub-ppm heavy metal content
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Nanofiltration purification technology
4️⃣ 7. Kunshan Kunhua Pharmaceutical
Headquarters: Jiangsu, China
Key Offering: Custom chemical solutions
Specializing in tailored formulations, Kunshan Kunhua provides modified guanidine hydrochloride products with enhanced solubility, stability, or compatibility characteristics for specialized applications.
Customization Options:
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Co-crystallized variants
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Buffered formulations
3️⃣ 8. Sihong Yuecheng Fine Chemical
Headquarters: Jiangsu, China
Key Offering: Integrated chemical production
With complete upstream capability from calcium cyanamide, Sihong Yuecheng maintains quality control from raw materials through final guanidine hydrochloride packaging—ensuring reliability for industrial buyers.
Supply Chain Control:
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In-house cyanoguanidine production
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Closed-loop solvent recovery
2️⃣ 9. Jinchi Chemical Co.
Headquarters: Shandong, China
Key Offering: Bulk industrial supply
Operating one of Asia’s largest dedicated facilities, Jinchi serves high-volume industrial users with consistent large-batch production and automated packaging solutions.
Scale Advantages:
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12,000+ MT annual output capacity
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Dedicated railway logistics
1️⃣ 10. Wuxi Kalider Industrial Co.
Headquarters: Jiangsu, China
Key Offering: Multi-grade global supply
Wuxi Kalider’s diverse product range serves applications from textile dyes to biopharmaceuticals, supported by international regulatory documentation and export capabilities.
Market Accessibility:
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GMP/ISO certified grade selection
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Export documentation support
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🔬 Market Outlook: Pharmaceutical Demands Drive Innovation
The guanidine hydrochloride sector is transforming through biopharmaceutical quality requirements and sustainable chemical manufacturing trends. While traditional industrial uses remain significant, advanced therapeutic applications present new technical challenges and opportunities.
📈 Key Market Development Factors:
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Biologic drug formulation requirements expanding
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Agrochemical market growth in developing regions
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Increasing purity standards across industries
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Supply chain resilience prioritization
Get Full Report Here: Guanidine Hydrochloride Market – View in Detailed Research Report
The leading producers profiled represent more than chemical suppliers—they’re critical partners in enabling pharmaceutical breakthroughs and industrial chemical solutions across diverse sectors.
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