The Global EDTA Solution Market was valued at USD 286.5 Million in 2023 and is projected to reach USD 398.2 Million by 2030, growing at a Compound Annual Growth Rate (CAGR) of 4.8% during the forecast period (2024–2030). This growth is driven by expanding applications in water treatment, pharmaceuticals, food preservation, and industrial processes where EDTA’s chelating properties are essential for metal ion control.

As industries seek safer and more effective metal sequestration solutions, the EDTA market is evolving with innovations in formulation and application-specific solutions. In this blog, we profile the Top 10 Companies in the EDTA Solution Industry—key manufacturers blending chemical expertise with sector-specific solutions across global markets.

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🔟 1. Biological Industries

Headquarters: Cromwell, Connecticut, USA
Key Offering: EDTA Solutions for Cell Culture & Biotechnology (0.05M-0.5M concentrations)

A leader in cell culture media and reagents, Biological Industries provides high-purity EDTA solutions optimized for biomedical research. Their sterile-filtered formulations meet ISO 13485 standards for critical life science applications.

Production Capabilities:

• GMP-compliant manufacturing facilities
• Global distribution to 50+ countries
• Custom molarity formulations (pH 8.0 standard)

Download FREE Sample Report: EDTA Solution Market – View in Detailed Research Report

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9️⃣ 2. Spectrum Chemical

Headquarters: Gardena, California, USA
Key Offering: USP/FCC/NF Grade EDTA Solutions (0.1M-1.0M)

Spectrum Chemical manufactures pharmaceutical-grade EDTA solutions compliant with demanding pharmacopeia standards. Their solutions are widely used in IV drugs, ophthalmic preparations, and cosmetic stabilizers.

Quality Certifications:

• FDA-registered facilities
• ISO 9001:2015 certified production
• Documented stability studies for all formulations

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8️⃣ 3. LabChem Inc.

Headquarters: Zelienople, Pennsylvania, USA
Key Offering: EDTA Titration Solutions & Buffer Systems

LabChem specializes in analytical-grade EDTA solutions for environmental testing and industrial quality control. Their 0.01M-0.1M standardized solutions are traceable to NIST reference materials.

Technical Advantages:

• ±1% concentration accuracy
• Color-coded stabilization packages
• Compatible with automated analyzers

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7️⃣ 4. GeneLinx International

Headquarters: Shirley, New York, USA
Key Offering: Molecular Biology Grade EDTA (0.5M stock solutions)

GeneLinx provides DNase/RNase-free EDTA solutions for nucleic acid extraction and purification workflows. Their products feature ultra-low heavy metal contamination (<0.1ppm).

Innovation Focus:

• EDTA-2Na formulations for buffer systems
• Ready-to-use aliquots for high-throughput labs
• PCR-grade purity certifications

Download FREE Sample Report: EDTA Solution Market – View in Detailed Research Report

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6️⃣ 5. Millipore Sigma

Headquarters: Burlington, Massachusetts, USA
Key Offering: EMPROVE® Bio & Pharma Grade EDTA

This life science giant offers EDTA solutions under stringent quality systems, with dedicated formulations for bioprocessing (upstream/downstream) and vaccine production.

Regulatory Support:

• EDMF/CEP documentation available
• Validated for classified cleanrooms
• Global regulatory support team

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5️⃣ 6. Inorganic Ventures

Headquarters: Christiansburg, Virginia, USA
Key Offering: Certified EDTA Reference Standards

Specializing in measurement science, Inorganic Ventures produces NIST-traceable EDTA solutions with <0.5% uncertainty for calibration and method validation.

Metrology Capabilities:

• ISO/IEC 17025 accredited lab
• Custom gravimetric formulations
• Stability-guaranteed packaging

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4️⃣ 7. Pulpdent Corporation

Headquarters: Watertown, Massachusetts, USA
Key Offering: Dental EDTA Chelating Gels (17% w/v)

Pulpdent pioneered EDTA solutions for endodontic procedures, with pH-optimized gels that combine EDTA’s demineralization with antimicrobial properties.

Clinical Advantages:

• Viscosity-controlled for canal penetration
• Synergistic formulations with surfactants
• Biological compatibility testing data

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3️⃣ 8. Titan Biotech Ltd.

Headquarters: Rajasthan, India
Key Offering: Cost-Effective Bulk EDTA Solutions

This Indian manufacturer supplies economical EDTA solutions to emerging markets, with capacities exceeding 5,000 metric tons annually across various concentrations.

Market Position:

• 45% market share in South Asia
• B2B custom compounding services
• REACH-compliant exports to EU

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2️⃣ 9. Hebei Extrand Biological Technology

Headquarters: Shijiazhuang, China
Key Offering: Industrial-Grade EDTA Solutions

A major Chinese producer, Hebei Extrand manufactures EDTA solutions for textile processing, paper bleaching, and boiler water treatment applications.

Production Scale:

• 10,000MT annual EDTA derivative capacity
• On-site raw material synthesis
• Wastewater EDTA recovery systems

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1️⃣ 10. Dojindo Laboratories

Headquarters: Kumamoto, Japan
Key Offering: Ultra-High Purity EDTA (>99.95%)

Dojindo sets the benchmark for purity with EDTA solutions containing less than 50ppb transition metals, critical for semiconductor manufacturing and nanotechnology.

Quality Leadership:

• ICP-MS certified impurity profiles
• Class 100 cleanroom filling
• Proprietary crystallization technology

Get Full Report Here: EDTA Solution Market – View in Detailed Research Report

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🧪 Outlook: EDTA Solutions Evolve with Industry 4.0 Requirements

The EDTA solution market is adapting to new industrial and regulatory realities, with smart manufacturing and sustainability becoming key differentiators.

📈 Critical Market Trends:

• Adoption of continuous manufacturing for EDTA solutions
• Growing demand for plant-based EDTA alternatives
• Automated quality control with inline analytics
• Tighter restrictions on EDTA discharge in wastewater

Get Full Report Here: EDTA Solution Market – View in Detailed Research Report

The featured companies demonstrate how specialized EDTA solutions are becoming—each carving distinct niches through formulation science and application expertise in this essential chelation chemistry market.