The Global Ammoniated Glycyrrhizin Market was valued at USD 150 Million in 2024 and is projected to reach USD 240 Million by 2032, growing at a Compound Annual Growth Rate (CAGR) of 6% during the forecast period (2025–2032). This growth is being driven by surging demand for natural sweeteners in the food & beverage industry, expanding applications in pharmaceutical formulations, and the rising preference for clean-label, plant-derived ingredients in cosmetics and personal care.

As the global market for natural active ingredients continues its upward trajectory, the spotlight is on the key producers and innovators who are leading in quality, scalability, and application development. In this blog, we profile the Top 10 Companies in the Ammoniated Glycyrrhizin Industry—a mix of established pharmaceutical giants, specialized biotechnology firms, and strategic suppliers shaping the future of this versatile compound.

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🔟 1. Ruihong Bio-technique (Shandong Ruihong Biotechnology Co., Ltd.)

Headquarters: Shandong, China
Key Offering: Food-grade, Pharmaceutical-grade, and Feed-grade Ammoniated Glycyrrhizin

Ruihong Bio-technique is a dominant force in the Asian glycyrrhizin market, recognized for its vertically integrated operations from licorice cultivation to high-purity extraction. The company serves a vast clientele across the pharmaceutical, confectionery, and health supplement industries, leveraging its significant production capacity to maintain a leading market share.

Key Innovations & Strategic Focus:

• Investment in supercritical CO2 extraction technology for higher purity yields
• Strong export network across Europe and Southeast Asia
• Focus on developing customized glycyrrhizin blends for specific customer formulations

Download FREE Sample Report:
Global Ammoniated Glycyrrhizin Market – View in Detailed Research Report

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9️⃣ 2. ELION Group

Headquarters: Henan, China
Key Offering: High-purity Pharmaceutical-grade Ammoniated Glycyrrhizin, Glycyrrhizic Acid

ELION Group has carved a niche as a specialist in high-purity botanical extracts, with ammoniated glycyrrhizin being a flagship product. Its stringent quality control processes make it a preferred supplier for major domestic and international pharmaceutical companies requiring certified active pharmaceutical ingredients (APIs).

Key Innovations & Strategic Focus:

• GMP-certified production facilities catering to stringent pharmacopoeia standards
• Active R&D in novel delivery systems for enhanced bioavailability in drugs
• Strategic partnerships with herbal medicine manufacturers

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8️⃣ 3. Hunan Dinuo Pharmaceutical Co., Ltd.

Headquarters: Hunan, China
Key Offering: Pharmaceutical-grade Ammoniated Glycyrrhizin, Finished Drug Formulations

Hunan Dinuo Pharmaceutical uniquely positions itself as both a bulk API producer and a manufacturer of finished dosage forms. This integration allows the company to deeply understand application nuances, driving innovation in both the supply of raw ammoniated glycyrrhizin and its use in hepatoprotective and anti-inflammatory medicines.

Key Innovations & Strategic Focus:

• Dual business model spanning API supply and proprietary drug manufacturing
• Focus on TCM (Traditional Chinese Medicine) modernization projects
• Expansion of production lines to meet growing export demand for pharmaceutical-grade material

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7️⃣ 4. Minophagen Pharmaceutical Co., Ltd.

Headquarters: Tokyo, Japan
Key Offering: Proprietary Pharmaceutical-grade Ammoniated Glycyrrhizin (Stronger Neo-Minophagen C®)

Minophagen is a veteran Japanese pharmaceutical company with a legendary brand built around glycyrrhizin. Its Stronger Neo-Minophagen C® injection and tablets are widely prescribed in Asia for chronic liver diseases, giving the company unparalleled clinical experience and brand recognition that underpins its premium position in the market.

Key Innovations & Strategic Focus:

• Decades of clinical data supporting efficacy and safety profiles
• Continuous process refinement for its flagship pharmaceutical product
• Exploring new therapeutic indications through ongoing clinical research

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6️⃣ 5. Xinjiang TIANSHAN Pharmaceutical Industry Co., Ltd.

Headquarters: Xinjiang, China
Key Offering: Food-grade & Pharmaceutical-grade Ammoniated Glycyrrhizin, Licorice Extracts

Benefiting from proximity to China’s primary licorice-growing regions in Xinjiang, TIANSHAN Pharmaceutical controls a critical part of the raw material supply chain. This strategic advantage allows for cost-effective production and a strong focus on commodity-grade ammoniated glycyrrhizin for the food and tobacco industries, alongside higher-grade pharmaceutical output.

Key Innovations & Strategic Focus:

• Backward integration into sustainable licorice root sourcing and cultivation
• Major supplier to the flavor and fragrance industry
• Investing in purification technologies to upgrade product portfolio

Download FREE Sample Report:
Global Ammoniated Glycyrrhizin Market – View in Detailed Research Report

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5️⃣ 6. Alps Pharmaceutical Ind. Co., Ltd.

Headquarters: Gifu, Japan
Key Offering: High-purity Ammoniated Glycyrrhizin for Cosmetics and Pharmaceuticals

Alps Pharmaceutical is a key Japanese player known for its high-quality standards and focus on the cosmetics and premium pharmaceutical sectors. The company emphasizes the skin-brightening and anti-inflammatory properties of ammoniated glycyrrhizin, marketing specialized grades to leading cosmetic brands.

Key Innovations & Strategic Focus:

• Development of cosmetic-grade ammoniated glycyrrhizin with enhanced stability
• Strong B2B relationships with Japanese and Korean cosmetic manufacturers
• Commitment to research on topical applications for skin health

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4️⃣ 7. Shandong Jincheng Pharmaceutical Co., Ltd.

Headquarters: Shandong, China
Key Offering: Ammoniated Glycyrrhizin, Glycyrrhetinic Acid, Various Pharmaceutical APIs

As a diversified pharmaceutical company, Shandong Jincheng has a significant chemical synthesis and natural extraction business unit. Its production of ammoniated glycyrrhizin is part of a broader portfolio, allowing for economies of scale and cross-technology expertise in purification that ensures consistent quality.

Key Innovations & Strategic Focus:

• Leveraging broad pharmaceutical manufacturing infrastructure for efficiency
• Export-oriented strategy with certifications for key international markets
• Investment in green chemistry principles for sustainable extraction

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3️⃣ 8. Jiangsu Tiansheng Pharmaceutical Co., Ltd.

Headquarters: Jiangsu, China
Key Offering: Pharmaceutical Intermediates and Ammoniated Glycyrrhizin

Jiangsu Tiansheng operates at the intersection of fine chemicals and natural products. The company applies advanced chemical engineering principles to the purification of ammoniated glycyrrhizin, resulting in products that meet the exacting specifications of modern pharmaceutical compounding.

Key Innovations & Strategic Focus:

• Focus on analytical method development for impurity profiling
• Serves as a critical API supplier for contract manufacturing organizations (CMOs)
• Active in developing derivative compounds for enhanced therapeutic effects

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2️⃣ 9. Gansu Yalan Pharmaceutical Co., Ltd.

Headquarters: Gansu, China
Key Offering: Licorice Extract Powders, Ammoniated Glycyrrhizin

Located in another key licorice-producing province, Gansu Yalan focuses on the upstream to midstream segments. The company is a reliable volume supplier of standard-grade ammoniated glycyrrhizin, particularly serving the domestic Chinese market for traditional remedies, herbal supplements, and basic food additive applications.

Key Innovations & Strategic Focus:

• Cost leadership strategy based on regional raw material access
• Strengthening quality systems to compete in more regulated segments
• Expanding product range to include more refined licorice derivatives

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1️⃣ 10. Ningxia Herb Laboratory (and other regional specialists)

Headquarters: Various across China (Ningxia, Inner Mongolia)
Key Offering: Regional-grade Ammoniated Glycyrrhizin, Crude Licorice Extracts

This segment comprises several regional specialists concentrated in China’s northwest. These companies are integral to the market’s ecosystem, often supplying semi-processed material to larger refiners or catering to local, price-sensitive end-users in the feed and traditional product sectors. Their deep knowledge of local cultivars and harvesting is invaluable.

Key Innovations & Strategic Focus:

• Deep expertise in local licorice botany and agronomy
• Act as important consolidators of raw material for the broader industry
• Increasingly adopting better extraction practices to meet rising quality expectations

Get Full Report Here:
Global Ammoniated Glycyrrhizin Market – View in Detailed Research Report

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🌍 Outlook: The Future of Ammoniated Glycyrrhizin is Integrated and Application-Led

The ammoniated glycyrrhizin market is evolving beyond a commoditized botanical extract. While bulk production for traditional uses remains substantial, the industry’s value growth is increasingly driven by innovation in high-margin, application-specific segments.

📈 Key Trends Shaping the Market:

• Pharmaceutical Integration: Leading companies are moving beyond API supply to develop proprietary finished dosage forms and explore new therapeutic indications through clinical trials.
• Clean-Label Demand: The global shift towards natural ingredients in food, beverage, and cosmetics is creating sustained, double-digit growth for food-grade and cosmetic-grade ammoniated glycyrrhizin.
• Quality & Standardization: Investment in advanced purification technologies (like chromatography and supercritical extraction) is becoming a key competitive differentiator to meet stringent international regulatory standards.
• Supply Chain Sustainability: Forward-thinking companies are investing in sustainable licorice cultivation and transparent sourcing to ensure long-term raw material security and appeal to environmentally conscious buyers.

The companies listed above are not only supplying a critical global ingredient—they are actively driving its evolution from a traditional herbal extract to a modern, versatile, and clinically relevant compound for the 21st century.

Get Full Report Here:
Global Ammoniated Glycyrrhizin Market – View in Detailed Research Report