The Global Squalene Market was valued at USD 117.5 Million in 2025 and is projected to reach USD 158.5 Million by 2032, growing at a Compound Annual Growth Rate (CAGR) of 4.6% during the forecast period (2025–2032). This expansion is primarily fueled by robust demand from the cosmetics and personal care sector, growing pharmaceutical applications, and the accelerating transition toward sustainable plant-based and biosynthetic squalene alternatives.

As consumer preferences shift toward natural, cruelty-free ingredients and the pharmaceutical industry explores advanced drug delivery systems, the focus is on the key suppliers who are pioneering sustainable sourcing and innovative production methods. In this blog, we profile the Top 10 Companies in the Squalene Industry—a mix of established marine oil processors, botanical extract specialists, and biotechnology innovators shaping the future of this versatile compound.

Download FREE Sample Report: Squalene Market – View in Detailed Research Report

---

🔟 1. Amyris, Inc.

Headquarters: Emeryville, California, USA
Key Offering: Bio-based Squalane (Neossance® Squalane)

Amyris is a pioneer in the sustainable squalene market, utilizing its proprietary yeast fermentation technology to produce high-purity squalane from sugarcane. This plant-based alternative has gained significant traction, offering a consistent, scalable, and ethically sourced ingredient for the cosmetics industry, effectively displacing traditional shark-derived squalene.

Sustainability Initiatives:

• Pioneering bio-fermentation for 100% plant-derived squalane

• Strategic partnerships with major cosmetic brands for sustainable sourcing

• Committed to a renewable carbon economy and reducing environmental impact

---

9️⃣ 2. Sophim

Headquarters: Peyruis, France
Key Offering: Phytosqualan (Olive-derived Squalane)

Sophim is a leading European supplier specializing in plant-based squalane derived from olive oil. The company has established itself as a key player in the high-end cosmetics market, providing a sustainable and high-quality alternative to animal-based squalene with excellent stability and skin compatibility.

Sustainability Initiatives:

• Expert in olive oil by-product valorization for squalane production

• Focus on traceability and eco-friendly extraction processes

---

8️⃣ 3. Kishimoto Special Liver Oil Co., Ltd.

Headquarters: Tokyo, Japan
Key Offering: Shark Liver Oil-derived Squalene

Kishimoto Special Liver Oil is one of Japan’s oldest and most established processors of marine-based squalene. With decades of experience, the company has deep expertise in the purification of high-grade squalene sourced from deep-sea shark liver oil, serving traditional markets.

Sustainability Initiatives:

• Adherence to regulated and sustainable fishing practices

• Investment in purification technologies to enhance product quality

---

7️⃣ 4. Maruha Nichiro Corporation

Headquarters: Tokyo, Japan
Key Offering: Marine and Plant-based Squalene

Maruha Nichiro, a global seafood and food product giant, is a major supplier of squalene. The company leverages its vast marine resources while also investing in the development of sustainable alternatives to cater to the evolving market demands for ethical sourcing.

Sustainability Initiatives:

• Exploring alternative squalene sources to reduce reliance on marine stocks

• Commitment to corporate sustainability goals and responsible sourcing

---

6️⃣ 5. Seadragon Marine Oils Limited

Headquarters: Nelson, New Zealand
Key Offering: Marine Oils and Squalene

Seadragon Marine Oils specializes in the production of refined marine oils, including squalene derived from shark liver oil. The company focuses on high-quality, traceable ingredients for the nutraceutical and cosmetics industries, with a strong presence in the Oceania region.

Sustainability Initiatives:

• Implementation of rigorous quality control and traceability systems

• Compliance with international marine resource management regulations

Download FREE Sample Report: Squalene Market – View in Detailed Research Report

---

5️⃣ 6. Nucelis LLC

Headquarters: San Diego, California, USA
Key Offering: Biosynthetic Squalene (Development Stage)

Nucelis LLC is an innovative biotechnology company developing sustainable ingredients through advanced metabolic engineering. The company is working on proprietary yeast strains to produce biosynthetic squalene, aiming to provide a highly pure and scalable alternative for pharmaceutical and cosmetic applications.

Sustainability Initiatives:

• Pioneering metabolic engineering for renewable chemical production

• Focus on creating a sustainable, non-animal-derived supply chain

---

4️⃣ 7. Arista Industries, Inc.

Headquarters: Wilton, Connecticut, USA
Key Offering: Natural Oils and Squalene

Arista Industries is a supplier of natural ingredients, including squalene and squalane, for cosmetic and pharmaceutical applications. The company sources both animal and plant-based variants, offering clients flexibility and a focus on high-purity, natural products.

Sustainability Initiatives:

• Providing certified and sustainably sourced oil options

• Emphasis on product transparency and customer-specific solutions

---

3️⃣ 8. Empresa Figueirense De Pesca, Lda

Headquarters: Figueira da Foz, Portugal
Key Offering: Shark Liver Oil Squalene

Empresa Figueirense De Pesca is a Portuguese company with a long history in fishing and marine product processing. It is a known supplier of squalene extracted from shark liver oil, serving European and international markets.

Sustainability Initiatives:

• Operates within the EU’s strict fisheries management framework

• Focuses on efficient processing to maximize resource utilization

---

2️⃣ 9. EKIZ Olive Oil & Soap Inc.

Headquarters: Izmir, Turkey
Key Offering: Olive Oil-derived Squalene

EKIZ leverages Turkey’s rich olive oil industry to produce squalene. As an integrated olive oil and soap manufacturer, the company utilizes by-products from its core operations to extract valuable compounds like squalene, promoting a circular economy model.

Sustainability Initiatives:

• Utilization of olive oil production by-products, reducing waste

• Promotion of local agricultural sourcing and natural ingredients

---

1️⃣ 10. New Zealand Green Health Ltd

Headquarters: Christchurch, New Zealand
Key Offering: Natural Health Products and Marine Oils

New Zealand Green Health is a supplier of natural health ingredients, including squalene sourced from the pristine waters around New Zealand. The company emphasizes the quality and purity of its marine-sourced products for the nutraceutical and cosmetics markets.

Sustainability Initiatives:

• Commitment to sustainable harvesting practices in New Zealand’s EEZ

• Focus on natural, minimally processed health ingredients

Get Full Report Here: Squalene Market – View in Detailed Research Report

---

🌍 Outlook: The Future of Squalene Is Sustainable and Science-Driven

The squalene market is undergoing a transformative shift. While marine-derived squalene still holds a significant share, the industry is rapidly investing in plant-based and biosynthetic alternatives, advanced extraction technologies, and transparent supply chains to meet ethical consumer demands.

📈 Key Trends Shaping the Market:

• Accelerated adoption of olive, sugarcane, and amaranth-derived squalene

• Biotech innovation leading to cost-effective biosynthetic production methods

• Growing pharmaceutical application in vaccine adjuvants and drug delivery systems

• Increased consumer and brand focus on cruelty-free and vegan certifications

Get Full Report Here: Squalene Market – View in Detailed Research Report

The companies listed above are not only supplying a vital ingredient to global markets—they are pioneering the sustainable evolution of the natural products industry.