The Global IPG Buffer Market was valued at USD 83.6 Million in 2025 and is projected to reach USD 119 Million by 2034, growing at a Compound Annual Growth Rate (CAGR) of 3.8% during the forecast period (2025–2034). This growth is being driven by the expansion of proteomics and genomics research, rising demand for advanced analytical techniques in life sciences, and the critical need for high-resolution protein separation in drug development and biomarker discovery.

As the life sciences industry advances toward more precise and personalized medicine, the spotlight is on the key reagent suppliers who are driving innovation, quality, and reproducibility in protein analysis. In this blog, we profile the Top 10 Companies in the IPG Buffer Industry—a mix of established life science giants and specialized electrophoresis pioneers shaping the future of global proteomics research.

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🔟 1. Cytiva

Headquarters: Marlborough, Massachusetts, USA
Key Offering: Immobiline™ DryStrips, IPG Buffers, 2D Electrophoresis Systems

Cytiva is a global leader in life sciences, providing a comprehensive portfolio of IPG Buffers and associated products for two-dimensional electrophoresis. Their Immobiline™ technology is renowned for creating highly stable and reproducible pH gradients, which are essential for accurate protein separation in complex biological samples. Cytiva serves academic institutions, pharmaceutical companies, and biotech firms worldwide.

Innovation Initiatives:

• Development of next-generation immobilized pH gradient chemistries

• Integration of IPG workflows with downstream mass spectrometry analysis

• Commitment to enhancing reproducibility and reducing run-to-run variability

Download FREE Sample Report: IPG Buffer Market – View in Detailed Research Report

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9️⃣ 2. Bio-Rad Laboratories

Headquarters: Hercules, California, USA
Key Offering: ReadyStrip™ IPG Strips, IPG Buffer, Protean® IEF Systems

Bio-Rad Laboratories is a dominant force in the electrophoresis market, offering a wide range of IPG Buffers and strips designed for high-resolution protein separation. Their products are known for exceptional lot-to-lot consistency and performance, making them a preferred choice for demanding proteomics applications in both research and quality control settings.

Innovation Initiatives:

• Advanced buffer formulations for improved protein solubility and resolution

• Automation-friendly IPG products for high-throughput laboratories

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8️⃣ 3. Thermo Fisher Scientific

Headquarters: Waltham, Massachusetts, USA
Key Offering: Pierce™ IPG Strips, IPG Buffers, Novex™ Electrophoresis Systems

Thermo Fisher Scientific’s extensive life sciences portfolio includes high-quality IPG Buffers that are integral to their comprehensive proteomics workflow solutions. Their buffers are optimized for compatibility with a wide range of sample types, from whole cell lysates to purified protein fractions, ensuring reliable performance across diverse applications.

Innovation Initiatives:

• Development of specialized buffers for challenging samples like membrane proteins

• Integration with cloud-based data analysis platforms for streamlined research

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7️⃣ 4. Merck KGaA

Headquarters: Darmstadt, Germany
Key Offering: IPG Strips, Ampholytes, Electrophoresis Reagents

Merck KGaA, through its MilliporeSigma division, is a key supplier of high-purity IPG Buffers and related electrophoresis consumables. The company’s strong focus on quality control and stringent manufacturing standards ensures that their buffers deliver consistent performance for critical research and diagnostic applications.

Innovation Initiatives:

• Expansion of product portfolio for clinical proteomics applications

• Collaborations with academic centers for method development and validation

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6️⃣ 5. Serva Electrophoresis GmbH

Headquarters: Heidelberg, Germany
Key Offering: Servalyt™ Precotes, IPG Buffers, Electrophoresis Chemicals

Serva Electrophoresis is a specialized manufacturer with deep expertise in electrophoresis products, including high-performance IPG Buffers. The company is particularly recognized for its innovative buffer chemistries that enable superior protein separation with minimal cathodic drift, making them valuable for detailed proteomic analyses.

Innovation Initiatives:

• Focus on ultra-narrow range IPG buffers for high-resolution applications

• Development of environmentally friendly buffer formulations

Download FREE Sample Report: IPG Buffer Market – View in Detailed Research Report

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5️⃣ 6. Sigma-Aldrich (Part of Merck KGaA)

Headquarters: St. Louis, Missouri, USA
Key Offering: Immobilized pH Gradient Buffers, Electrophoresis Grade Reagents

Sigma-Aldrich provides research-grade IPG Buffers that are widely used in academic and industrial laboratories globally. Their products are characterized by high purity and reliability, supporting a broad spectrum of proteomics research from basic science to applied biotechnology applications.

Innovation Initiatives:

• Continuous improvement of buffer stability and shelf-life

• Development of application-specific buffer formulations

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4️⃣ 7. GE Healthcare Life Sciences (Now Cytiva)

Headquarters: Chicago, Illinois, USA
Key Offering: IPGphor System, Immobiline DryStrips, Buffer Kits

Although now part of Cytiva, the legacy GE Healthcare Life Sciences portfolio continues to be influential in the IPG Buffer market. Their products are designed for ease of use and reproducibility, making 2D electrophoresis accessible to laboratories of all sizes and expertise levels.

Innovation Initiatives:

• Integration of IPG technology with automated protein analysis systems

• Development of user-friendly buffer kits for standardized protocols

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3️⃣ 8. Lonza Group Ltd.

Headquarters: Basel, Switzerland
Key Offering: Electrophoresis Reagents, Protein Separation Tools

Lonza offers specialized IPG Buffers as part of their broader portfolio of life science research tools. While not their primary focus, their buffers are valued for quality and are often used in conjunction with their cell biology and bioprocessing products for comprehensive research workflows.

Innovation Initiatives:

• Application-focused buffer development for specific research areas

• Quality assurance protocols ensuring batch-to-batch consistency

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2️⃣ 9. Agilent Technologies

Headquarters: Santa Clara, California, USA
Key Offering: Protein Electrophoresis Supplies, Buffer Solutions

Agilent Technologies provides high-quality IPG Buffers that complement their extensive analytical instrumentation portfolio. Their buffers are designed to deliver reliable performance for researchers who require consistent protein separation results for downstream analysis using Agilent’s LC/MS systems.

Innovation Initiatives:

• Development of buffers optimized for specific protein classes

• Integration with automated sample preparation workflows

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1️⃣ 10. Harvard Apparatus

Headquarters: Holliston, Massachusetts, USA
Key Offering: Electrophoresis Equipment, Buffer Solutions, Consumables

Harvard Apparatus serves the research community with reliable IPG Buffers and electrophoresis supplies. While a smaller player compared to industry giants, they are recognized for their customer-focused approach and ability to provide specialized solutions for unique research requirements.

Innovation Initiatives:

• Custom buffer formulation services for specialized applications

• Focus on educational and research institution markets

Get Full Report Here: IPG Buffer Market – View in Detailed Research Report

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🔬 Outlook: The Future of IPG Buffers Is More Precise and Integrated

The IPG Buffer market is undergoing a significant evolution. While traditional electrophoresis remains fundamental, the industry is investing in advanced formulations, automation-compatible products, and integration with multi-omics platforms.

📈 Key Trends Shaping the Market:

• Development of ultra-narrow range buffers for high-resolution protein separation

• Integration with automated liquid handling systems for high-throughput screening

• Growing demand for application-specific buffers in clinical proteomics

• Increasing focus on reproducibility and standardization in research workflows

Get Full Report Here: IPG Buffer Market – View in Detailed Research Report

The companies listed above are not only supplying essential research reagents—they’re enabling the next generation of proteomic discoveries that will transform medicine and biotechnology.