The Global 3,5-Difluoroacetophenone Market was valued at USD 43.5 Million in 2025 and is projected to reach USD 68.2 Million by 2034, growing at a Compound Annual Growth Rate (CAGR) of 5.1% during the forecast period. This growth is primarily driven by its indispensable role as a high-value chemical intermediate in the synthesis of active pharmaceutical ingredients (APIs) and advanced agrochemicals, coupled with expanding applications in material science.

As the pharmaceutical and agrochemical industries increasingly rely on sophisticated molecular building blocks, the spotlight is on the specialized chemical manufacturers who ensure a consistent, high-purity supply of critical intermediates. In this blog, we profile the Top 10 Companies in the 3,5-Difluoroacetophenone Industry—a group of leading chemical suppliers and innovators shaping the future of modern synthesis.

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🔟 1. Glentham Life Sciences

Headquarters: Corsham, Wiltshire, United Kingdom
Key Offering: High-Purity 3,5-Difluoroacetophenone (NLT 98%), Custom Synthesis

Glentham Life Sciences is a globally recognized supplier of fine chemicals and raw materials for life science research. The company offers high-purity 3,5-Difluoroacetophenone, catering primarily to pharmaceutical R&D and specialty chemical applications, with a strong focus on quality and supply chain reliability for its international clientele.

Innovation & Quality Initiatives:

• Maintenance of extensive chemical catalog with stringent quality control

• Supply chain partnerships ensuring global distribution

• Commitment to supporting academic and industrial research with high-grade intermediates

Download FREE Sample Report: 3,5-Difluoroacetophenone Market – View in Detailed Research Report

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9️⃣ 2. Shaoxin Catsyn Co., Ltd

Headquarters: Shaoxing, Zhejiang, China
Key Offering: 3,5-Difluoroacetophenone (various grades), Fluorinated Intermediates

Shaoxin Catsyn is a specialized manufacturer of fluorinated aromatic compounds, positioning itself as a key player in the Chinese market for 3,5-Difluoroacetophenone. The company leverages its expertise in fluorine chemistry to serve both domestic and international markets in the pharmaceutical and agrochemical sectors.

Innovation & Quality Initiatives:

• Specialization in complex fluorination processes

• Focus on cost-effective production for competitive pricing

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8️⃣ 3. Suzhou Qihang Biotechnology Co., Ltd

Headquarters: Suzhou, Jiangsu, China
Key Offering: 3,5-Difluoroacetophenone, Pharmaceutical Intermediates

Suzhou Qihang Biotechnology specializes in the research, development, and production of pharmaceutical intermediates and fine chemicals. The company has established a strong reputation for supplying high-quality 3,5-Difluoroacetophenone to the growing API manufacturing sector in China and abroad.

Innovation & Quality Initiatives:

• Integration of R&D with manufacturing capabilities

• Adherence to international quality standards for chemical purity

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7️⃣ 4. Hangzhou Hairui Chemical Co., Ltd

Headquarters: Hangzhou, Zhejiang, China
Key Offering: 3,5-Difluoroacetophenone (Purity 97%-98%), Custom Synthesis Services

Hangzhou Hairui Chemical is a prominent manufacturer of fluorinated compounds and other fine chemicals. The company is a significant supplier of 3,5-Difluoroacetophenone, with a focus on scaling production to meet rising global demand from the pharmaceutical industry.

Innovation & Quality Initiatives:

• Continuous process optimization for improved yield and purity

• Expansion of production capacity to secure market position

Download FREE Sample Report: 3,5-Difluoroacetophenone Market – View in Detailed Research Report

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6️⃣ 5. Beijing Golden Olive Company

Headquarters: Beijing, China
Key Offering: 3,5-Difluoroacetophenone, Fine Chemical Exports

Beijing Golden Olive Company operates as a supplier and exporter of fine chemicals, including 3,5-Difluoroacetophenone. The company connects Chinese chemical production with global markets, serving a diverse customer base in research and industrial applications.

Innovation & Quality Initiatives:

• Strategic sourcing from qualified manufacturers

• Robust logistics network for international distribution

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5️⃣ 6. Cangzhou Pure Science Co., Ltd

Headquarters: Cangzhou, Hebei, China
Key Offering: 3,5-Difluoroacetophenone, Specialty Aromatic Ketones

Cangzhou Pure Science is a chemical manufacturer with a focus on producing specialty intermediates like 3,5-Difluoroacetophenone. The company contributes to the market with a production base in a major Chinese chemical industry zone, benefiting from integrated supply chains.

Innovation & Quality Initiatives:

• Focus on purity control for demanding applications

• Competitive positioning within the domestic Chinese market

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4️⃣ 7. Hangzhou Fluoro Pharmaceutical Co., Ltd

Headquarters: Hangzhou, Zhejiang, China
Key Offering: 3,5-Difluoroacetophenone, Fluorinated Pharmaceutical Intermediates

As the name suggests, Hangzhou Fluoro Pharmaceutical specializes in fluorine-containing compounds tailored for the pharmaceutical industry. The company’s expertise makes it a relevant producer of 3,5-Difluoroacetophenone, targeting high-value API synthesis pathways.

Innovation & Quality Initiatives:

• Specialized knowledge in fluorination chemistry relevant to drug discovery

• Alignment of product portfolio with pharmaceutical industry needs

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3️⃣ 8. Capot Chemical Co., Ltd

Headquarters: Hangzhou, Zhejiang, China
Key Offering: 3,5-Difluoroacetophenone, BOC-Amino Acids, Advanced Intermediates

Capot Chemical is a well-established supplier of advanced chemical intermediates, including 3,5-Difluoroacetophenone. The company serves a global clientele in pharmaceuticals, agrochemistry, and material science, supported by strong R&D and manufacturing capabilities.

Innovation & Quality Initiatives:

• Investment in R&D for new synthetic routes

• Certifications and quality systems catering to international markets

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2️⃣ 9. Biosynth Carbosynth

Headquarters: Staad, Switzerland
Key Offering: High-Purity 3,5-Difluoroacetophenone, Research Chemicals

Biosynth Carbosynth is a leading global supplier of life science reagents, carbohydrates, and fine chemicals. The company offers 3,5-Difluoroacetophenone primarily to the research and development sector, emphasizing high purity and documentation for scientific use.

Innovation & Quality Initiatives:

• Extensive product catalog for research institutions

• Stringent analytical controls and batch-specific data

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1️⃣ 10. Thermo Fisher Scientific (Alfa Aesar)

Headquarters: Waltham, Massachusetts, USA
Key Offering: 3,5-Difluoroacetophenone (Lab-scale to bulk), Fine Chemicals

Through its Alfa Aesar brand, Thermo Fisher Scientific is a major distributor of research chemicals, including 3,5-Difluoroacetophenone. While not a primary manufacturer, its global logistics network and reputation for quality make it a critical channel for researchers and developers requiring reliable access to this intermediate.

Innovation & Quality Initiatives:

• Global supply chain ensuring availability

• High standard of quality assurance for research applications

Get Full Report Here: 3,5-Difluoroacetophenone Market – View in Detailed Research Report

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🔬 Outlook: The Future of 3,5-Difluoroacetophenone is Driven by Specialization and Purity

The 3,5-Difluoroacetophenone market is evolving beyond a standard chemical commodity into a strategically important intermediate. While volume growth remains steady, the industry’s value is increasingly defined by technological expertise in fluorination, adherence to stringent purity standards, and the ability to support complex synthesis pathways in regulated industries.

📈 Key Trends Shaping the Market:

• Increasing demand for NLT 98% purity grade from the pharmaceutical sector

• Geographical concentration of production in China, with global distribution networks

• Growing R&D into new applications within material science and electronics

• Strategic partnerships between intermediate suppliers and end-user manufacturers

Get Full Report Here: 3,5-Difluoroacetophenone Market – View in Detailed Research Report

The companies listed above are not only supplying a critical chemical intermediate—they’re enabling the innovation pipelines of the pharmaceutical and agrochemical industries worldwide.