The Global Neutral Cellulase Enzyme Market was valued at USD 422.5 Million in 2025 and is projected to reach USD 752.8 Million by 2034, growing at a Compound Annual Growth Rate (CAGR) of 6.4% during the forecast period (2024–2034). This significant growth is primarily driven by the escalating demand for sustainable industrial processes, the expansion of the textile industry, and continuous advancements in enzyme engineering that enhance efficiency and stability.

As industries worldwide pivot towards green chemistry and eco-friendly solutions, neutral cellulase enzymes have become indispensable biocatalysts. Operating optimally in a neutral pH range (6.0-7.5), these enzymes efficiently hydrolyze cellulose without the need for harsh acids or alkalis. In this blog, we profile the Top 10 Companies in the Neutral Cellulase Enzyme Industry—a select group of biotechnology innovators and specialized manufacturers shaping the future of sustainable textile processing, animal nutrition, and biofuel production.

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🔟 1. Novozymes A/S

Headquarters: Bagsværd, Denmark
Key Offering: Cellic® CTec3, Novozyme 476 (Specialty Neutral Cellulases)

Novozymes stands as the global leader in industrial enzymes, with a commanding presence in the neutral cellulase segment. The company’s enzymes are widely used in textiles for bio-polishing and denim finishing, in agriculture for feed enhancement, and in biorefineries for biomass conversion. Its strong R&D focus continually yields advanced enzyme formulations with higher activity and stability.

Innovation Initiatives:

• Pioneering research in fungal and microbial enzyme production
• Development of low-water-consumption enzymes for textile applications
• Strategic partnerships with major brands in apparel and biofuel sectors

Download FREE Sample Report:
Neutral Cellulase Enzyme Market – View in Detailed Research Report

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9️⃣ 2. AB Enzymes GmbH

Headquarters: Darmstadt, Germany
Key Offering: ROHALASE® SEP, Veron® CE (Neutral Cellulase Blends)

A subsidiary of Associated British Foods, AB Enzymes is a major European player renowned for high-purity enzyme solutions. The company’s neutral cellulase products are critical for improving dough handling in baking, enhancing animal feed digestibility, and providing stone-wash effects in denim manufacturing with reduced environmental impact.

Innovation Initiatives:

• Focus on thermostable and pH-stable enzyme variants
• Expansion into specialty applications for food and feed industries

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8️⃣ 3. Genencor (International) Inc. (A DuPont Subsidiary)

Headquarters: Palo Alto, California, USA
Key Offering: Accellerase® DUET, Accellerase® TRIO (Cellulase Complexes)

Genencor, operating under DuPont’s industrial biosciences division, is a powerhouse in developing enzyme technologies for biomass conversion. Its Accellerase® series is specifically engineered for efficient hydrolysis of lignocellulosic biomass into fermentable sugars, playing a pivotal role in the advanced biofuel and biochemical sectors.

Innovation Initiatives:

• Leading R&D in engineered enzyme cocktails for biorefineries
• Commitment to reducing enzyme costs for commercial-scale biofuel production

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7️⃣ 4. Advanced Enzyme Technologies Ltd.

Headquarters: Thane, Maharashtra, India
Key Offering: Enzylon AA, Fermcell (Neutral Cellulases for Textiles & Feed)

Advanced Enzyme Technologies is a leading Indian biotech company with a significant global footprint. It offers a diverse portfolio of neutral cellulases that cater to the booming textile industry in Asia-Pacific, as well as to animal nutrition and food processing markets, emphasizing cost-effective and high-performance solutions.

Innovation Initiatives:

• Investment in fermentation technology for scalable production
• Focus on developing enzymes for digestive health and wellness products

Download FREE Sample Report:
Neutral Cellulase Enzyme Market – View in Detailed Research Report

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6️⃣ 5. Dyadic International, Inc.

Headquarters: Jupiter, Florida, USA
Key Offering: C1-based Neutral Cellulase Expression Platform

Dyadic International is a unique biotechnology company focused on developing and deploying its proprietary C1 microbial protein production platform. This technology enables the cost-effective production of a wide range of enzymes, including high-performance neutral cellulases, for industrial and bio-pharmaceutical applications.

Innovation Initiatives:

• Licensing of the C1 platform for third-party enzyme development
• Research into hyper-producing fungal strains for improved yields

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5️⃣ 6. Megazyme Ltd. (A Subsidiary of Neogen Corporation)

Headquarters: Bray, County Wicklow, Ireland
Key Offering: Analytical Grade Neutral Cellulases, Enzyme Assay Kits

Megazyme specializes in the production of high-purity enzymes for analytical and research applications. While its primary market is diagnostic and research laboratories, the company’s expertise in enzyme purification and characterization supports the broader industrial enzyme sector by providing reliable standards and assay methods.

Innovation Initiatives:

• Development of precise, standardized enzyme assay kits
• Supply of certified reference materials for quality control in industrial enzyme production

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4️⃣ 7. BASF SE (Enzymes Business)

Headquarters: Ludwigshafen, Germany
Key Offering: Bioenzyme formulations for Detergents, Textiles

BASF, a global chemical giant, incorporates enzymes into its extensive portfolio of products for various industries. Its neutral cellulases are key components in detergent formulations for color care and in textile processing to achieve softness and prevent pilling, aligning with the demand for efficient and sustainable consumer products.

Innovation Initiatives:

• Integration of enzymes into multifunctional product formulations
• Focus on enhancing performance in cold-water washing applications

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3️⃣ 8. Jiangsu Boli Bioproducts Co., Ltd.

Headquarters: Wuxi, Jiangsu, China
Key Offering: BL Series Neutral Cellulases for Textile and Pulp & Paper

As a major Chinese enzyme manufacturer, Jiangsu Boli Bioproducts supplies a wide range of industrial enzymes to domestic and international markets. The company’s neutral cellulases are extensively used in the local textile industry for fabric biostoning and bio-polishing, capitalizing on China’s position as a global manufacturing hub.

Innovation Initiatives:

• Scaled production to meet high-volume demand from Asian textile mills
• Competitive pricing strategies for emerging markets

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2️⃣ 9. Sunson Industry Group Co., Ltd.

Headquarters: Ningxia, China
Key Offering: Neutral Cellulase NS- 81028, NS-81029

Sunson Industry Group is a prominent enzyme producer in China with a strong focus on the textile and alcohol industries. Its neutral cellulase products are tailored for efficient desizing and bio-polishing processes, helping textile manufacturers reduce chemical usage, water consumption, and environmental footprint.

Innovation Initiatives:

• Development of enzymes for combined textile processing steps
• Expansion of production capacity to serve growing Asian markets

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1️⃣ 10. ENMEX (Enzimáticas Mexicanas S.A. de C.V.)

Headquarters: Naucalpan, State of Mexico, Mexico
Key Offering: Specialty Neutral Cellulases for Food and Beverage

ENMEX is a leading enzyme company in Latin America, producing a variety of enzymes for the food, feed, and beverage industries. Its neutral cellulases are used in juice extraction and clarification processes, helping processors increase yield and improve product quality while adhering to natural and clean-label trends.

Innovation Initiatives:

• Tailoring enzymes for regional agricultural produce like tropical fruits
• Focus on technical support and customized solutions for local clients

Read Full Report:
Neutral Cellulase Enzyme Market – View in Detailed Research Report

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🌍 Outlook: The Future of Neutral Cellulase Enzymes Is Efficient and Sustainable

The neutral cellulase enzyme market is undergoing a significant transformation, fueled by the global push for sustainability. While traditional applications in textiles and animal feed continue to dominate, the industry is witnessing substantial investment in R&D for more efficient enzyme cocktails and novel applications in waste valorization and biorefining.

📈 Key Trends Shaping the Market:

• R&D Focus on engineered enzymes with higher specific activity and thermostability
• Expansion of textile bio-processing in Asia-Pacific, driven by environmental regulations
• Growing adoption in second-generation biofuel production as technology matures
• Strategic collaborations between enzyme manufacturers and end-user industries to develop application-specific solutions

Read Full Report:
Neutral Cellulase Enzyme Market – View in Detailed Research Report

The companies listed above are not only supplying essential biocatalysts—they’re actively pioneering the green transformation of multiple global industries.