The Global Thulium-167 Market was valued at US$ 7.6 Million in 2025 and is projected to reach US$ 13.7 Million by 2034, growing at a Compound Annual Growth Rate (CAGR) of 8.6% during the forecast period (2026-2034). This growth is being driven by increasing demand for advanced medical imaging and radiotherapy solutions, rising investment in nuclear research, and the expanding applications of radioisotopes in scientific and industrial fields.

As the global healthcare and research sectors increasingly rely on specialized radioactive materials, the focus turns to the key producers and innovators who ensure a stable and high-purity supply of critical isotopes. In this blog, we profile the Top 10 Companies in the Thulium-167 Industry—a mix of renowned national laboratories, research institutions, and emerging commercial suppliers shaping the future of nuclear medicine and technology.

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🔟 1. CERN (European Organization for Nuclear Research)

Headquarters: Meyrin, Geneva, Switzerland
Key Offering: Thulium-167 isotope production via high-energy accelerator facilities, fundamental nuclear research

CERN is one of the world’s premier centers for nuclear and particle physics research. While its primary mission is fundamental science, its advanced accelerator complex, including the Isotope Mass Separator On-Line (ISOLDE) facility, is capable of producing a wide array of radioisotopes, including Thulium-167, for research applications.

Research and Development Initiatives:

• Pioneering research in exotic isotope production and characterization

• Collaborations with medical research institutions to explore therapeutic applications of isotopes

• Providing high-purity isotope beams for international scientific experiments

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9️⃣ 2. Paul Scherrer Institute (PSI)

Headquarters: Villigen, Switzerland
Key Offering: Thulium-167 production, research-grade isotopes, nuclear physics services

The Paul Scherrer Institute is Switzerland’s largest research institute for natural and engineering sciences. Its extensive facilities, including the Swiss Spallation Neutron Source (SINQ), are used for materials science and fundamental research, with capabilities for producing isotopes like Thulium-167.

Research and Development Initiatives:

• Advanced research into neutron capture reactions for isotope production

• Development of novel separation and purification techniques for medical isotopes

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8️⃣ 3. Oak Ridge National Laboratory (ORNL)

Headquarters: Oak Ridge, Tennessee, USA
Key Offering: Thulium-167 from the High Flux Isotope Reactor (HFIR), isotope R&D services

Operated by the U.S. Department of Energy, ORNL is a powerhouse in isotope production. Its High Flux Isotope Reactor is one of the most powerful research reactors in the world, capable of producing significant quantities of Thulium-167 and other rare isotopes for medical, industrial, and scientific use.

Research and Development Initiatives:

• Leading the DOE’s Isotope Program for securing domestic supply of critical isotopes

• Innovation in target fabrication and chemical processing to enhance isotope yield and purity

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7️⃣ 4. Los Alamos National Laboratory (LANL)

Headquarters: Los Alamos, New Mexico, USA
Key Offering: Accelerator-produced Thulium-167, nuclear science research capabilities

LANL has a long-standing reputation in nuclear science and national security. Its accelerator facilities are utilized for producing a range of isotopes. The laboratory conducts research into the properties and potential applications of Thulium-167, particularly for defense-related and energy research projects.

Research and Development Initiatives:

• Fundamental studies on nuclear structure and decay properties of rare earth isotopes

• Exploration of isotopes for next-generation radiation detection technologies

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6️⃣ 5. SCK CEN (The Belgian Nuclear Research Centre)

Headquarters: Mol, Belgium
Key Offering: Reactor-based Thulium-167, radiopharmaceutical R&D

SCK CEN is a leading European center for nuclear research, with a strong focus on the medical applications of radioactivity. Its BR2 reactor is a key asset for producing medical isotopes, and the institute is involved in research programs that could utilize Thulium-167 for therapeutic and diagnostic purposes.

Research and Development Initiatives:

• Development of targeted alpha therapy and other advanced cancer treatments

• Partnering with pharmaceutical companies to translate research into clinical applications

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5️⃣ 6. Institute for Radioelements (IRE)

Headquarters: Fleurus, Belgium
Key Offering: Medical isotope production, including potential for Thulium-based radiopharmaceuticals

While known for Molybdenum-99 production, IRE is a significant player in the European medical isotope market. Its expertise in reactor-based production and radiochemistry positions it as a potential future supplier of Thulium-167 as demand for novel therapeutic isotopes grows.

Research and Development Initiatives:

• Investment in expanding production capabilities for emerging medical isotopes

• Focus on ensuring a resilient supply chain for European healthcare

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4️⃣ 7. Canadian Nuclear Laboratories (CNL)

Headquarters: Chalk River, Ontario, Canada
Key Offering: Isotope production services, nuclear science expertise

CNL manages Canada’s historic Chalk River Laboratories, a site with a long legacy in nuclear science and isotope production. With renewed investment and modernized facilities, CNL is enhancing its capacity to produce a diverse portfolio of isotopes, including rare earth isotopes like Thulium-167 for research markets.

Research and Development Initiatives:

• Reinvigorating isotope production pipelines with new accelerator and reactor capabilities

• Collaborative research with academia on the applications of novel isotopes

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3️⃣ 8. ITER Organization

Headquarters: Saint-Paul-lès-Durance, France
Key Offering: Research into fusion-produced neutrons for isotope generation

Although not a direct producer, the ITER project’s research into nuclear fusion has profound implications for future isotope production. The high-energy neutrons generated by fusion could, in the future, provide a powerful new method for producing isotopes like Thulium-167, representing a potential long-term shift in production technology.

Research and Development Initiatives:

• Groundbreaking research on neutron activation and transmutation processes

• International collaboration to advance fusion science and its ancillary benefits

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2️⃣ 9. National Institute of Radiological Sciences (NIRS-QST), Japan

Headquarters: Chiba, Japan
Key Offering: Heavy-ion accelerator-produced isotopes, radiobiological research

As part of Japan’s National Institutes for Quantum Science and Technology, NIRS is a leader in radiation medicine. Its heavy-ion accelerators are used for both cancer treatment (hadron therapy) and for fundamental research, including the production and study of rare isotopes for medical science.

Research and Development Initiatives:

• Developing next-generation radiotherapeutics using targeted isotopes

• Extensive research on the biological effects of different types of radiation

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1️⃣ 10. Joint Institute for Nuclear Research (JINR)

Headquarters: Dubna, Moscow Oblast, Russia
Key Offering: Thulium-167 from research reactors and cyclotrons, fundamental science

JINR is an international research center renowned for its discoveries in nuclear physics. Its facilities, including the IBR-2 pulsed fast reactor and the U-400 cyclotron, enable the production of a wide spectrum of isotopes. JINR contributes significantly to the global knowledge base on the properties of Thulium-167 and other rare isotopes.

Research and Development Initiatives:

• Discovery and synthesis of new elements and isotopes

• International scientific collaborations to explore nuclear structure and reactions

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🔬 Outlook: The Future of Thulium-167 Is Pioneering and Precise

The Thulium-167 market is evolving within a specialized and technologically advanced sector. While current production is primarily for research, the industry is exploring new applications that could significantly increase demand, particularly in targeted alpha therapy for cancer and advanced scientific instrumentation.

📈 Key Trends Shaping the Market:

• Growing R&D investment in targeted radionuclide therapy, creating demand for novel isotopes like Thulium-167

• Modernization of aging nuclear research infrastructure in North America and Europe to secure isotope supply chains

• Increased international collaboration to share the high costs and risks associated with fundamental nuclear research

• Exploration of accelerator-driven systems as a complementary method to reactor-based isotope production

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The institutions listed above are not only producing a critical scientific resource—they’re laying the groundwork for the next generation of medical and technological breakthroughs.