The Global 3,5-Difluorobenzyl Bromide Market was valued at USD 48.2 Million in 2025 and is projected to reach USD 68.9 Million by 2034, growing at a Compound Annual Growth Rate (CAGR) of 5.8% during the forecast period (2024–2030). This significant growth is fueled by increasing demand from the pharmaceutical sector, expanding applications in agrochemical synthesis, and the compound’s critical role as a key building block in advanced material science.

As the chemical industry advances toward more complex and specialized molecules, the focus intensifies on the key manufacturers who ensure the consistent supply and high purity of essential intermediates. In this analysis, we profile the Top 10 Companies in the 3,5-Difluorobenzyl Bromide Market—a group of specialized chemical suppliers and innovators shaping the future of fine chemical synthesis.

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🔟 1. Glentham Life Sciences

Headquarters: Corsham, Wiltshire, United Kingdom
Key Offering: High-Purity 3,5-Difluorobenzyl Bromide (98% and 99%)

Glentham Life Sciences is a leading global supplier of fine chemicals and biochemicals, including a comprehensive portfolio of fluorinated building blocks. Their 3,5-Difluorobenzyl Bromide is widely used in pharmaceutical research and development, offering researchers a reliable source for this critical intermediate.

Technical Capabilities:

• Strict quality control ensuring batch-to-batch consistency

• Global distribution network serving academic and industrial clients

• Custom synthesis services for specialized derivatives

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9️⃣ 2. Boroncore LLC

Headquarters: Champaign, Illinois, USA
Key Offering: Boronic Acid Derivatives and Fluorinated Intermediates

Boroncore specializes in boron-containing compounds and has expanded its expertise to include fluorinated benzyl bromides. The company serves the pharmaceutical and materials science markets with high-purity intermediates essential for Suzuki-Miyaura cross-coupling reactions and other advanced synthetic methodologies.

Technical Capabilities:

• Expertise in organofluorine chemistry

• Scale-up capabilities from gram to kilogram quantities

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8️⃣ 3. Aromsyn Co.,Ltd

Headquarters: Wuhan, Hubei, China
Key Offering: Aromatic Fluorine Compounds and Custom Synthesis

Aromsyn has established itself as a key manufacturer of fluorinated aromatic compounds in the Asian market. The company’s strategic location in China’s chemical manufacturing hub enables competitive pricing and reliable supply chain management for global customers.

Technical Capabilities:

• Integrated manufacturing from raw materials to finished products

• Strong R&D focus on novel fluorination techniques

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7️⃣ 4. Beijing Golden Olive Company

Headquarters: Beijing, China
Key Offering: Pharmaceutical Intermediates and Fine Chemicals

Beijing Golden Olive Company is a comprehensive supplier of fine chemicals with significant production capacity for fluorinated compounds. Their expertise in handling sensitive reagents like benzyl bromides makes them a preferred partner for pharmaceutical companies requiring high-quality intermediates.

Technical Capabilities:

• GMP-compliant manufacturing facilities

• Strong export orientation with global logistics expertise

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6️⃣ 5. Changzhou Huanling Chemical Co., Ltd

Headquarters: Changzhou, Jiangsu, China
Key Offering: Specialty Fluorine Chemicals and Custom Synthesis

Changzhou Huanling Chemical has developed specialized expertise in fluorinated compounds, particularly benzyl bromide derivatives. The company’s strategic location in the Yangtze River Delta chemical industry cluster provides advantages in raw material sourcing and manufacturing efficiency.

Technical Capabilities:

• Advanced purification technologies for high-purity products

• Technical support for customer-specific applications

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5️⃣ 6. Shaoxin Catsyn Co., Ltd

Headquarters: Shaoxing, Zhejiang, China
Key Offering: Catalysts and Specialty Chemical Intermediates

Shaoxin Catsyn specializes in catalysts and chemical intermediates, with a growing portfolio of fluorinated building blocks. The company’s focus on catalytic processes enables efficient and environmentally friendly production methods for compounds like 3,5-Difluorobenzyl Bromide.

Technical Capabilities:

• Catalyst development expertise

• Process optimization for cost-effective manufacturing

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4️⃣ 7. Thermo Fisher Scientific

Headquarters: Waltham, Massachusetts, USA
Key Offering: Laboratory Chemicals and Research Compounds

While primarily known as a laboratory supplier, Thermo Fisher Scientific’s chemical division provides high-purity 3,5-Difluorobenzyl Bromide for research applications. Their global distribution network and quality assurance protocols make them a trusted source for academic and industrial researchers.

Technical Capabilities:

• Stringent analytical characterization of all products

• Comprehensive documentation and certificates of analysis

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3️⃣ 8. Sigma-Aldrich (Merck KGaA)

Headquarters: Darmstadt, Germany
Key Offering: High-Purity Research Chemicals

As part of Merck KGaA, Sigma-Aldrich offers 3,5-Difluorobenzyl Bromide through its extensive catalog of research chemicals. The company’s reputation for quality and reliability makes it a preferred supplier for pharmaceutical companies engaged in early-stage drug discovery.

Technical Capabilities:

• Global quality standards compliance

• Extensive product portfolio supporting diverse research needs

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2️⃣ 9. Tokyo Chemical Industry Co., Ltd. (TCI)

Headquarters: Tokyo, Japan
Key Offering: Fine Chemicals and Organic Synthesis Reagents

TCI is a leading global supplier of organic synthesis reagents, including a comprehensive range of fluorinated compounds. The company’s strong technical expertise and consistent product quality have established it as a key player in the 3,5-Difluorobenzyl Bromide market.

Technical Capabilities:

• Extensive experience in fluorine chemistry

• Strong customer support and technical documentation

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1️⃣ 10. Combi-Blocks Inc.

Headquarters: San Diego, California, USA
Key Offering: Building Blocks for Medicinal Chemistry

Combi-Blocks specializes in providing chemical building blocks for drug discovery and development. Their portfolio includes high-purity 3,5-Difluorobenzyl Bromide, supported by comprehensive analytical data and flexible packaging options suitable for research and development scale.

Technical Capabilities:

• Focus on medicinal chemistry applications

• Flexible scale from milligram to multi-kilogram quantities

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🔬 Outlook: The Future of 3,5-Difluorobenzyl Bromide Is Application-Driven and Technologically Advanced

The 3,5-Difluorobenzyl Bromide market is experiencing transformative growth, driven by its expanding applications in pharmaceutical synthesis, agrochemical development, and advanced materials. While traditional applications continue to dominate current demand, the market is evolving toward more specialized uses and higher purity requirements.

📈 Key Trends Shaping the Market:

• Increasing adoption in kinase inhibitor synthesis for oncology drugs

• Growing demand for high-purity (≥99%) grades for pharmaceutical GMP applications

• Expansion of production capacity in Asia-Pacific region

• Development of greener synthesis routes with improved atom economy

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3,5-Difluorobenzyl Bromide Market – View in Detailed Research Report

The companies profiled above are not only supplying a critical chemical intermediate—they’re enabling innovation across multiple high-technology industries through their expertise in fluorine chemistry and commitment to quality.