The Global Feed Nucleotides Market was valued at USD 342.8 Million in 2023 and is projected to reach USD 546.2 Million by 2029, growing at a Compound Annual Growth Rate (CAGR) of 7.9% during the forecast period (2024–2029). This robust growth is being propelled by the surging global demand for animal protein, a heightened focus on animal health and welfare, and the rapid expansion of the aquaculture sector, all of which are driving the adoption of advanced nutritional supplements like nucleotides.

As the animal nutrition industry pivots toward precision feeding and sustainable production, the role of specialized feed additives has never been more critical. Nucleotides, essential for cellular function and immune response, are at the forefront of this transformation. In this blog, we profile the Top 10 Companies in the Feed Nucleotides Industry—a blend of global chemical giants, specialized ingredient suppliers, and biotechnology innovators shaping the future of livestock and aquaculture health.

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🔟 1. Adisseo France SAS

Headquarters: Commentry, France
Key Offering: NutriNucleo, Rovabio, Methionine & Vitamin Solutions

Adisseo is a global leader in animal nutrition, renowned for its innovative feed additives. The company’s nucleotide product line, particularly under the NutriNucleo brand, is designed to enhance gut health, improve immune function, and boost overall performance in poultry, swine, and aquaculture species. Their strong R&D focus ensures scientifically-backed solutions for modern farming challenges.

Innovation & Sustainability Initiatives:

• Significant investment in biotechnology for nucleotide production

• Development of sustainable, high-efficacy nutritional solutions

• Commitment to reducing the environmental footprint of animal production

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Feed Nucleotides Global Market – View in Detailed Research Report

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9️⃣ 2. Ajinomoto Co., Inc.

Headquarters: Tokyo, Japan
Key Offering: Nucleotide feed supplements, Amino Acids, Flavor Enhancers

Ajinomoto leverages its deep expertise in amino acid and nucleotide biochemistry to produce high-purity feed-grade nucleotides. As a major global producer, the company supplies ingredients that support critical biological processes in young animals and during periods of stress, contributing to improved growth rates and feed efficiency.

Innovation & Sustainability Initiatives:

• Pioneering research in the metabolic benefits of nucleotides

• Integration of nucleotide production with its core amino acid business for synergistic effects

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8️⃣ 3. Leiber GmbH

Headquarters: Hafenstraße, Germany
Key Offering: Specialty Yeast Products, Brewers’ Yeast, Nucleotide-rich Yeast Extracts

Leiber GmbH specializes in producing high-value yeast-based products for animal nutrition. Their nucleotide offerings are derived from specialized yeast extracts, which are a natural and highly bioavailable source. These products are particularly valued in aquaculture and pet food for enhancing palatability and supporting immune health.

Innovation & Sustainability Initiatives:

• Focus on natural, fermentation-based nucleotide sources

• Sustainable production practices utilizing by-products from the brewing industry

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7️⃣ 4. Lesaffre Group

Headquarters: Marcq-en-Barœul, France
Key Offering: Yeast Derivatives, Probiotics, Nucleotide-rich Yeast Extracts

As a global key player in fermentation, Lesaffre produces a wide range of yeast-derived ingredients for animal nutrition. Their nucleotide products are integral to their portfolio, supporting gut flora balance and strengthening the animal’s natural defenses, which is crucial in antibiotic-reduction programs.

Innovation & Sustainability Initiatives:

• Extensive R&D in yeast genomics and fermentation technologies

• Commitment to providing solutions for antibiotic-free animal production

Download FREE Sample Report:
Feed Nucleotides Global Market – View in Detailed Research Report

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6️⃣ 5. ADM (Archer-Daniels-Midland Company)

Headquarters: Chicago, Illinois, USA
Key Offering: Animal Nutrition Solutions, Yeast Products, NutriPass Protected Nutrients

ADM’s animal nutrition division offers a comprehensive portfolio that includes nucleotide-rich ingredients, often derived from yeast. Their global scale and extensive supply chain enable them to serve diverse markets, providing solutions that enhance animal health, performance, and producer profitability.

Innovation & Sustainability Initiatives:

• Investment in innovative production processes for consistent quality

• Focus on sustainable sourcing and reducing the carbon footprint of feed ingredients

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5️⃣ 6. BASF SE

Headquarters: Ludwigshafen, Germany
Key Offering: Vitamins, Enzymes, Feed Additives, Nutritional Ingredients

BASF, a leading chemical company, applies its vast expertise to the animal nutrition market. While its portfolio is broad, it offers high-quality ingredients that can include nucleotide precursors and supports the overall nutritional matrix necessary for optimal animal health and efficient production systems.

Innovation & Sustainability Initiatives:

• Strong commitment to research in animal physiology and nutrition

• Developing integrated solutions that promote animal wellness and sustainable farming

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4️⃣ 7. Biovet JSC

Headquarters: Peshtera, Bulgaria
Key Offering: Feed Additives, Preservatives, Mycotoxin Binders, Nutritional Supplements

Biovet JSC is a prominent manufacturer of feed additives in Eastern Europe, with a growing focus on advanced nutritional supplements like nucleotides. The company aims to enhance animal performance and health through a scientifically formulated product range, catering primarily to the European and neighboring markets.

Innovation & Sustainability Initiatives:

• Expansion of product portfolio to include more specialized health-promoting additives

• Investments in modern production facilities to meet increasing quality standards

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3️⃣ 8. Cargill Inc.

Headquarters: Wayzata, Minnesota, USA
Key Offering: Provimi Animal Nutrition, Premixes, Feed Additives, Aqua Feeds

Cargill’s animal nutrition business, Provimi, is a global leader providing tailored solutions that often incorporate nucleotide technology. Their focus is on precision nutrition, using data and research to create feed programs that maximize health and efficiency for livestock and aquaculture customers worldwide.

Innovation & Sustainability Initiatives:

• Leveraging digital tools for customized nutritional recommendations

• Commitment to sustainable agriculture and reducing environmental impact across the value chain

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2️⃣ 9. Lallemand Animal Nutrition

Headquarters: Montreal, Quebec, Canada
Key Offering: Yeast Derivatives, Probiotics, Mycotoxin Management, Natural Growth Promoters

Lallemand specializes in microbial-based solutions for animal health and nutrition. Their yeast derivative products are a natural source of nucleotides and other bioactive compounds, which are used to support digestive health and immune function, particularly in monogastric animals and ruminants.

Innovation & Sustainability Initiatives:

• Dedicated R&D in yeast and bacteria for animal nutrition applications

• Promotion of natural alternatives to in-feed antibiotics

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1️⃣ 10. Novus International, Inc.

Headquarters: St. Charles, Missouri, USA
Key Offering: Methionine, Trace Minerals, Enzymes, Specialty Feed Additives

Novus International is a leading provider of health and nutrition solutions for the global animal agriculture industry. Their comprehensive approach includes products and programs designed to enhance animal well-being, with nucleotide-related components often integrated into broader nutritional strategies to address specific challenges like early-life development and immune support.

Innovation & Sustainability Initiatives:

• Focus on innovative solutions that improve nutrient utilization and animal resilience

• Sustainability goals centered on improving the efficiency of animal protein production

Get Full Report Here:
Feed Nucleotides Global Market – View in Detailed Research Report

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🌍 Outlook: The Future of Feed Nucleotides Is Smarter and More Integrated

The feed nucleotides market is experiencing a significant evolution. Driven by the global push for more efficient and sustainable animal protein production, nucleotide supplementation is transitioning from a niche application to a mainstream strategy for enhancing livestock and aquaculture health.

📈 Key Trends Shaping the Market:

• Rising demand in aquaculture, as nucleotides are proven to enhance survival rates and growth in fish and shrimp

• Integration of nucleotides into comprehensive gut health programs aimed at reducing antibiotic use

• Advancements in fermentation technology leading to more cost-effective and sustainable production

• Growing consumer awareness driving demand for meat, eggs, and fish from animals raised with high welfare and health standards

Get Full Report Here:
Feed Nucleotides Global Market – View in Detailed Research Report

The companies listed above are not only supplying critical nutrition—they are enabling a more resilient and sustainable future for global animal agriculture.