The Global Squalene Market was valued at USD 117.5 Million in 2025 and is projected to reach USD 158.5 Million by 2032, growing at a Compound Annual Growth Rate (CAGR) of 4.6% during the forecast period (2025–2032). This growth is being driven by the expanding cosmetics industry, rising demand for natural ingredients, and the accelerating adoption of Sustainable Plant-Based Squalene solutions across pharmaceutical and personal care sectors.

As the market transforms toward ethical sourcing and sustainable production, the spotlight is on the key suppliers who are driving innovation, purity standards, and eco-friendly supply chains. In this blog, we profile the Top 10 Companies in the Squalene Industry—a mix of biotechnology pioneers, marine oil specialists, and plant-based innovators shaping the future of this vital ingredient.

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🔟 1. Amyris, Inc.

Headquarters: Emeryville, California, USA
Key Offering: Bio-fermented Squalane (Neossance® Squalane)

Amyris is a leading biotechnology company that has revolutionized squalene production through its proprietary fermentation technology. Using sustainably sourced sugarcane, Amyris produces a high-purity, 100% plant-derived squalane (a hydrogenated form of squalene) that is identical to its natural counterpart but vegan and renewable. Their innovative approach has positioned them as a key supplier to major global beauty brands seeking sustainable alternatives to shark-derived squalene.

Sustainability Initiatives:

• Pioneering bio-fermentation to eliminate reliance on shark liver oil

• Commitment to carbon-negative manufacturing processes

• Strategic partnerships with leading cosmetic and personal care companies

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Squalene Market – View in Detailed Research Report

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9️⃣ 2. Sophim

Headquarters: Peyruis, France
Key Offering: Phytosqualan (Olive-derived Squalane)

Sophim is a prominent European manufacturer specializing in plant-derived active ingredients for cosmetics. The company is renowned for its Phytosqualan, a high-purity squalane sourced exclusively from olive oil. This sustainable alternative is highly valued in the premium skincare market for its excellent stability, compatibility, and emollient properties, offering a clear ethical advantage over traditional animal sources.

Sustainability Initiatives:

• Exclusive focus on olive oil as a renewable, traceable raw material

• Implementation of eco-friendly extraction and hydrogenation processes

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8️⃣ 3. Maruha Nichiro Corporation

Headquarters: Tokyo, Japan
Key Offering: Shark Liver Oil-derived Squalene, Olive Squalene

Maruha Nichiro is one of Japan’s largest seafood companies and a long-standing major player in the squalene market, historically sourced from deep-sea shark liver oil. In response to market shifts, the company has strategically diversified its portfolio to include plant-based squalene, leveraging its extensive processing expertise and global distribution network to serve both traditional and evolving market segments.

Sustainability Initiatives:

• Investment in R&D for sustainable squalene sourcing

• Adherence to international fisheries management and traceability standards

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7️⃣ 4. Kishimoto Special Liver Oil Co., Ltd.

Headquarters: Tokyo, Japan
Key Offering: High-Purity Shark Liver Oil Squalene

Kishimoto Special Liver Oil is a specialized manufacturer with decades of experience in refining high-purity squalene from shark liver oil. The company has built a strong reputation for quality and consistency, primarily supplying the pharmaceutical and high-end cosmetic industries. It maintains a significant presence in markets where marine-derived squalene is still utilized under strict regulatory frameworks.

Sustainability Initiatives:

• Focus on purity and quality control for specialized applications

• Compliance with CITES regulations and sustainable sourcing policies

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6️⃣ 5. Seadragon Marine Oils Limited

Headquarters: Nelson, New Zealand
Key Offering: Marine-derived Squalene, Refined Fish Oils

Seadragon Marine Oils is a leading Australasian producer of marine oils, including squalene sourced from deep-water shark species. The company emphasizes traceability and sustainable harvesting practices, catering to a niche market that requires specific grades of marine-derived squalene for pharmaceutical adjuvants and specialty cosmetics.

Sustainability Initiatives:

• Commitment to sustainable fishing practices and quota management

• Investment in purification technologies to maximize yield and quality

Download FREE Sample Report:
Squalene Market – View in Detailed Research Report

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5️⃣ 6. Nucelis LLC

Headquarters: San Diego, California, USA
Key Offering: Biosynthetic Squalene via Yeast Fermentation

Nucelis is an innovative biotechnology firm developing sustainable, cost-effective squalene production through advanced yeast strain engineering and fermentation. Their platform aims to produce high-purity squalene that is free from agricultural constraints and environmental concerns associated with both marine and plant sourcing, targeting the pharmaceutical and cosmetic markets.

Sustainability Initiatives:

• Development of proprietary microbial fermentation platforms

• Focus on creating a scalable, land-independent production method

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4️⃣ 7. Empresa Figueirense De Pesca

Headquarters: Figueira da Foz, Portugal
Key Offering: Shark Liver Oil Squalene

Empresa Figueirense De Pesca is a Portuguese company with a long history in marine product processing, including the extraction of squalene from shark liver oil. Operating within the strict regulatory environment of the European Union, the company supplies high-grade squalene primarily to European pharmaceutical and cosmetic manufacturers.

Sustainability Initiatives:

• Operation under stringent EU environmental and fishing regulations

• Exploration of sustainable sourcing alternatives for long-term viability

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3️⃣ 8. Arista Industries, Inc.

Headquarters: Wilton, Connecticut, USA
Key Offering: Squalene (Shark and Plant-derived), Squalane

Arista Industries is a global supplier of natural oils and derivatives, offering a diverse portfolio that includes both shark-derived and plant-based squalene/squalane. The company serves a broad range of industries, including cosmetics, nutraceuticals, and pharmaceuticals, by providing various grades to meet specific application requirements.

Sustainability Initiatives:

• Expansion of plant-based squalene offerings to meet customer demand

• Supply chain transparency and quality assurance programs

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2️⃣ 9. EKIZ Olive Oil & Soap Inc.

Headquarters: Izmir, Turkey
Key Offering: Olive Oil-derived Squalene

EKIZ is a vertically integrated Turkish company that utilizes its olive oil production by-products to extract squalene. This approach provides a sustainable and cost-effective source of plant-based squalene, capitalizing on the region’s rich olive oil industry and offering a traceable “field-to-formula” ingredient for the cosmetic market.

Sustainability Initiatives:

• Utilization of olive oil pomace, a by-product, reducing waste

• Promotion of a circular economy model within the agriculture sector

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1️⃣ 10. New Zealand Green Health Ltd.

Headquarters: Christchurch, New Zealand
Key Offering: Olive Squalene, Amaranth Seed Oil

New Zealand Green Health specializes in natural ingredients sourced from both local and international botanicals. The company supplies plant-derived squalene, primarily from olive oil, to the health, wellness, and cosmetic industries. Their focus on purity and natural origins aligns with the growing consumer preference for clean-label and ethically produced products.

Sustainability Initiatives:

• Commitment to sourcing from sustainable and certified growers

• Development of organic and non-GMO product lines

Get Full Report Here:
Squalene Market – View in Detailed Research Report

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🌍 Outlook: The Future of Squalene Is Plant-Based and Pharmaceutical-Grade

The squalene market is undergoing a fundamental transformation. While marine-derived squalene maintains a presence in specific applications, the industry is rapidly investing in sustainable alternatives, advanced fermentation technologies, and pharmaceutical-grade purification processes.

📈 Key Trends Shaping the Market:

• Accelerated shift from shark-derived to plant-based (olive, sugarcane) and biosynthetic squalene

• Growing application in vaccine adjuvants and advanced drug delivery systems

• Increasing stringency of regulations and consumer demand for cruelty-free, vegan cosmetics

• Consolidation and strategic partnerships to secure sustainable supply chains

Get Full Report Here:
Squalene Market – View in Detailed Research Report

The companies listed above are not only supplying a vital global ingredient—they’re pioneering the sustainable and ethical evolution of the beauty and healthcare industries.