The Global Chlorohexidine Gluconate Market was valued at USD 342.8 Million in 2025 and is projected to reach USD 495.3 Million by 2030, growing at a Compound Annual Growth Rate (CAGR) of 5.8% during the forecast period (2024–2030). This robust growth is fueled by escalating global demand for infection prevention, heightened awareness of oral hygiene, and the rising adoption of Chlorohexidine Gluconate (CHG) across healthcare, consumer goods, and industrial applications.

As the healthcare industry prioritizes patient safety and hygiene standards, the role of effective antiseptic agents has become paramount. In this blog, we profile the Top 10 Companies in the Chlorohexidine Gluconate Industry—a diverse group of chemical manufacturers, healthcare giants, and consumer goods leaders shaping the future of global antiseptic solutions.

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🔟 1. BASF SE

Headquarters: Ludwigshafen, Germany
Key Offering: Pharmaceutical-grade Chlorhexidine Gluconate Solution (20% w/w)

BASF is a leading global supplier of high-purity Chlorhexidine Gluconate, serving as a critical raw material for pharmaceutical and personal care manufacturers. Their production adheres to stringent pharmacopoeial standards (USP, EP), making them a preferred partner for high-quality antiseptic formulations.

Innovation and Quality Initiatives:

• Investment in green chemistry for sustainable production processes

• Global supply chain optimization to ensure consistent raw material availability

• Technical support for downstream manufacturers in formulations and compliance

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Chlorohexidine Gluconate Global Market – View in Detailed Research Report

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9️⃣ 2. 3M Company

Headquarters: Saint Paul, Minnesota, USA
Key Offering: 3M™ DuraPrep™ Surgical Solution, 3M™ Avagard™ Hand Antiseptic

3M is a dominant force in the healthcare antiseptics market, integrating Chlorhexidine Gluconate into its advanced surgical and patient prepping portfolios. Their solutions are renowned for efficacy, ease of use, and compliance with global healthcare protocols.

Innovation and Quality Initiatives:

• Proprietary delivery systems for controlled release and prolonged antimicrobial activity

• Ongoing clinical research to validate efficacy against emerging pathogens

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8️⃣ 3. Ecolab Inc.

Headquarters: Saint Paul, Minnesota, USA
Key Offering: Ecolab® Surgical Hand Scrub, skin antiseptics for healthcare and food service

Ecolab provides comprehensive infection prevention solutions to healthcare and hospitality sectors globally. Their Chlorhexidine Gluconate-based products are integral to surgical site infection prevention programs in thousands of hospitals.

Innovation and Quality Initiatives:

• Focus on water-saving formulations in surgical scrubs

• Integrated digital monitoring for hand hygiene compliance in healthcare facilities

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7️⃣ 4. DuPont de Nemours, Inc. (Formerly E. I. DuPont)

Headquarters: Wilmington, Delaware, USA
Key Offering: DuPont™ Chlorhexidine Gluconate for pharmaceutical applications

DuPont’s expertise in specialty chemicals extends to high-purity Chlorhexidine Gluconate, catering to the stringent needs of the pharmaceutical and medical device industries. Their products are critical in manufacturing antiseptic wipes, preoperative scrubs, and oral care solutions.

Innovation and Quality Initiatives:

• Development of stable CHG formulations for challenging environments

• Strategic R&D partnerships with global health organizations

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6️⃣ 5. Henkel AG & Co. KGaA

Headquarters: Düsseldorf, Germany
Key Offering: Bode® antiseptics, Chlorhexidine Gluconate-based wound care and skin cleansers

Through its Bode Chemie subsidiary (part of Henkel’s Adhesive Technologies segment), Henkel is a key player in medical-grade antiseptics. Their products are widely used in hospitals, dental practices, and for consumer first-aid applications across Europe and Asia.

Innovation and Quality Initiatives:

• Expansion of CHG-based product lines for over-the-counter (OTC) markets

• Commitment to sustainable packaging for all antiseptic products

Download FREE Sample Report:
Chlorohexidine Gluconate Global Market – View in Detailed Research Report

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5️⃣ 6. Kao Corporation

Headquarters: Tokyo, Japan
Key Offering: Biore® UV Perfect Series (with antiseptic properties), professional hygiene products

Kao Corporation leverages Chlorhexidine Gluconate in its consumer and professional hygiene segments. While prominent in personal care, their technical expertise in surfactants and antimicrobials supports sophisticated CHG formulations for the Asian market.

Innovation and Quality Initiatives:

• Development of mild, non-irritating CHG formulations for sensitive skin

• R&D into synergistic effects of CHG with other natural antimicrobials

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4️⃣ 7. ABC Compounding Company

Headquarters: Americus, Georgia, USA
Key Offering: Custom-compounded Chlorhexidine Gluconate solutions for veterinary and niche medical use

ABC Compounding specializes in tailor-made antiseptic solutions, filling critical gaps for specific veterinary and small-batch medical applications. They offer flexibility in concentration and formulation that larger producers may not.

Innovation and Quality Initiatives:

• Expertise in USP <797> and <800> compliance for sterile compounding

• Focus on serving underserved markets like veterinary medicine and specialized dermatology

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3️⃣ 8. Medical Chemical Corporation

Headquarters: Torrance, California, USA
Key Offering: Triad® Disinfectant Towelettes, Medi-Chlor® pre-operative cleansers

Medical Chemical Corporation is a dedicated manufacturer of infection control products, with Chlorhexidine Gluconate as a core component of its disposable wipe and cleanser lines. They serve laboratories, clinics, and hospitals with reliable, ready-to-use antiseptic products.

Innovation and Quality Initiatives:

• Specialization in convenient, single-use antiseptic formats

• Rigorous quality control for maximum microbial efficacy

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2️⃣ 9. Xttrium Laboratories

Headquarters: Chicago, Illinois, USA
Key Offering: Pharmaceutical-grade Chlorhexidine Gluconate API (Active Pharmaceutical Ingredient)

Xttrium Laboratories is a key supplier of Active Pharmaceutical Ingredients, including high-purity Chlorhexidine Gluconate. They support the pharmaceutical industry’s need for compliant, traceable, and potent raw materials for antiseptic drug manufacturing.

Innovation and Quality Initiatives:

• FDA-registered and cGMP-compliant manufacturing facilities

• Investment in analytical method development for purity testing

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1️⃣ 10. Ashland Global Holdings Inc.

Headquarters: Wilmington, Delaware, USA
Key Offering: Chlorhexidine Gluconate solutions for cosmetic, pharmaceutical, and healthcare applications

Ashland’s Specialty Ingredients segment supplies versatile Chlorhexidine Gluconate to a broad spectrum of industries. Their technical expertise helps formulators in personal care and pharmaceuticals overcome challenges related to stability and compatibility.

Innovation and Quality Initiatives:

• Development of multi-functional CHG blends for enhanced product performance

• Global regulatory support for product registration and market access

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Chlorohexidine Gluconate Global Market – View in Detailed Research Report

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🌍 Outlook: The Future of Chlorhexidine Gluconate Is Integrated and Intelligent

The Chlorhexidine Gluconate market is evolving beyond a standard antiseptic to a sophisticated, integrated component of modern healthcare and personal wellness. While its core antimicrobial properties remain foundational, the industry is investing in advanced formulations, combination products, and smart delivery systems.

📈 Key Trends Shaping the Market:

• Rising demand for antiseptic products in homecare and self-medication segments

• Development of CHG-impregnated medical devices (e.g., catheters, dressings) for proactive infection control

• Stringent regulatory landscape demanding higher purity and documented efficacy

• Growing application in veterinary medicine and animal health

Get Full Report Here:
Chlorohexidine Gluconate Global Market – View in Detailed Research Report

The companies listed above are not only supplying a critical antimicrobial agent—they are enabling a safer, more hygienic world across healthcare, consumer, and industrial landscapes.