Top 10 Companies in the Global Sodium Hyaluronate Market (2026): Industry Leaders Fueling Cosmetic and Pharmaceutical Innovation

In Business Insights
January 26, 2026


The Global Sodium Hyaluronate Market was valued at USD 432.28 Million in 2023 and is projected to reach USD 1240.00 Million by 2029, growing at a Compound Annual Growth Rate (CAGR) of 19.20% during the forecast period. This remarkable growth is fueled by soaring demand in the cosmetics and personal care industry, an aging global population seeking advanced skincare and anti-aging solutions, and expanding therapeutic applications in ophthalmology, orthopedics, and dermatology.

As the market for this versatile biopolymer expands, a select group of companies is leading the charge through innovation, strategic expansion, and technological advancement in production. In this blog, we profile the Top 10 Companies in the Sodium Hyaluronate Industry—a mix of biotechnology pioneers, established pharmaceutical players, and specialized manufacturers shaping the future of hyaluronic acid applications worldwide.

Download FREE Sample Report: Global Sodium Hyaluronate Market – View in Detailed Research Report


🔟 1. Bloomage Biotech

Headquarters: Jinan, Shandong, China
Key Offering: Hyaluronic Acid Raw Materials, Sodium Hyaluronate for Cosmetics, Pharmaceuticals, and Food

Bloomage Biotech is the world’s largest producer of hyaluronic acid, commanding a significant global market share. The company has a vertically integrated supply chain, from microbial fermentation research to the production of a wide range of hyaluronic acid-based products for various industries.

Innovation and Market Strategy:

  • Pioneer in microbial fermentation technology for high-purity HA
  • Extensive R&D portfolio with hundreds of patents
  • Strategic expansion into high-value medical and functional food applications

9️⃣ 2. Kewpie Corporation

Headquarters: Tokyo, Japan
Key Offering: High-Purity Sodium Hyaluronate, Pharmaceutical-Grade HA, Hyaluronic Acid for Nutraceuticals

Kewpie, a leading Japanese food and ingredient company, is a major global supplier of hyaluronic acid, primarily derived from microbial fermentation. The company leverages its expertise in bio-fermentation to produce high-quality HA for cosmetic, pharmaceutical, and nutraceutical markets.

Innovation and Market Strategy:

  • Long-standing expertise in HA production since the 1980s
  • Focus on high-purity, low-molecular-weight HA for enhanced bioavailability
  • Strong presence in the premium Japanese and Asian cosmetic markets

8️⃣ 3. Contipro a.s.

Headquarters: Dolní Dobrouč, Czech Republic
Key Offering: Ophthalmic Viscosurgical Devices (OVDs), Dermal Fillers, Advanced HA Derivatives

Contipro is a leading European biotechnology company specializing in the research, development, and production of hyaluronic acid and its derivatives. The company is renowned for its innovative and patented technologies, particularly in the medical and advanced cosmetic sectors.

Innovation and Market Strategy:

  • Development of unique, patented HA cross-linking technologies
  • Strong focus on medical devices, including ophthalmic and orthopedic applications
  • Strategic partnerships with global aesthetic and pharmaceutical companies

Download FREE Sample Report: Global Sodium Hyaluronate Market – View in Detailed Research Report


7️⃣ 4. Fidia Farmaceutici S.p.A.

Headquarters: Abano Terme, Italy
Key Offering: Hyaluronic Acid-based Medical Devices, Viscosupplementation Products, Pharmaceutical-Grade HA

Fidia Farmaceutici is a globally recognized Italian pharmaceutical company with a long history of innovation in hyaluronic acid-based therapeutics. The company is a key player in the orthopedic market, particularly for intra-articular injections for osteoarthritis.

Innovation and Market Strategy:

  • Leadership in hyaluronic acid-based viscosupplementation
  • Extensive clinical data supporting the efficacy of its medical products
  • Global distribution network for its pharmaceutical and medical device portfolio

6️⃣ 5. Seikagaku Corporation

Headquarters: Tokyo, Japan
Key Offering: Pharmaceutical-Grade Sodium Hyaluronate, Research-Grade HA, Viscosupplements

Seikagaku Corporation is a prominent Japanese company specializing in the research and development of glycosaminoglycans, including hyaluronic acid. The company has a strong foothold in the pharmaceutical sector, supplying high-purity HA for therapeutic applications.

Innovation and Market Strategy:

  • Deep expertise in the biochemistry of glycosaminoglycans
  • Focus on developing novel HA-based therapeutics for joint and eye diseases
  • Strong B2B relationships with pharmaceutical and biotechnology firms

5️⃣ 6. HTL Biotechnology

Headquarters: Javené, France
Key Offering: HYAJECT® Biomedical-Grade HA, Contract Manufacturing, Custom HA Solutions

HTL Biotechnology is a French specialist in the fermentation, purification, and chemical modification of bio-polymers, with hyaluronic acid as its flagship product. The company provides high-quality HA to the medical device, pharmaceutical, and cosmetic industries.

Innovation and Market Strategy:

  • Specialization in high-value, biomedical-grade HA
  • Strong capabilities in contract development and manufacturing (CDMO)
  • Strategic focus on regulatory compliance for global markets (FDA, CE)

4️⃣ 7. Shandong Focuschem Biotech Co., Ltd.

Headquarters: Jinan, Shandong, China
Key Offering: Cosmetic-Grade Sodium Hyaluronate, Food-Grade HA, Hyaluronic Acid Powder

Shandong Focuschem Biotech is a significant Chinese manufacturer of hyaluronic acid, specializing in the production of various grades of HA for the cosmetic and nutraceutical industries. The company is known for its competitive pricing and large-scale production capacity.

Innovation and Market Strategy:

  • Cost-effective production leveraging China’s manufacturing scale
  • Broad portfolio catering to diverse molecular weight requirements
  • Growing export business to international cosmetic ingredient suppliers

3️⃣ 8. Fufeng Group Company Limited

Headquarters: Shandong, China
Key Offering: Fermentation-Based Biochemicals, Sodium Hyaluronate, Amino Acids

Fufeng Group is a major Chinese producer of fermentation-based products, including xanthan gum, monosodium glutamate, and hyaluronic acid. The company applies its large-scale fermentation expertise to produce HA for the food and cosmetic sectors.

Innovation and Market Strategy:

  • Leverages core competency in industrial-scale fermentation processes
  • Integrated production from raw materials to finished HA products
  • Focus on expanding into higher-value segments of the HA market

Read Full Report: Global Sodium Hyaluronate Market – View in Detailed Research Report


2️⃣ 9. Shandong Awa Biopharm Co., Ltd.

Headquarters: Jinan, Shandong, China
Key Offering: Sodium Hyaluronate, Chondroitin Sulfate, Heparin Sodium

Shandong Awa Biopharm is a specialized manufacturer of biochemical products, with a focus on glycosaminoglycans like hyaluronic acid and chondroitin sulfate. The company supplies raw materials to the pharmaceutical, health food, and cosmetic industries.

Innovation and Market Strategy:

  • Specialization in a portfolio of bioactive carbohydrates
  • Strong quality control systems for pharmaceutical and food applications
  • Strategic positioning as a reliable B2B supplier in the global market

1️⃣ 10. China Eastar Group

Headquarters: Zibo, Shandong, China
Key Offering: Cosmetic Ingredients, Sodium Hyaluronate, Plant Extracts

China Eastar Group is a diversified chemical and ingredient company with a growing presence in the hyaluronic acid market. The company produces cosmetic-grade HA and supplies it to domestic and international manufacturers of beauty and personal care products.

Innovation and Market Strategy:

  • Diversified chemical portfolio providing operational synergies
  • Focus on the rapidly growing Asian cosmetic ingredient market
  • Investment in expanding HA production capacity to meet rising demand

🌍 Outlook: The Future of Sodium Hyaluronate is Diversified and High-Tech

The sodium hyaluronate market is experiencing a transformative phase, driven by technological advancements and the exploration of novel applications. While the cosmetic industry remains the largest consumer, the most significant growth potential lies in advanced medical applications and innovative drug delivery systems.

📈 Key Trends Shaping the Market:

  • Rising demand for low-molecular-weight and cross-linked HA for enhanced skin penetration and longer-lasting dermal fillers.
  • Expansion of HA applications in tissue engineering, wound healing, and regenerative medicine.
  • Growing consumer awareness and demand for HA-infused nutraceuticals and functional foods for joint and skin health.
  • Increasing investment in sustainable and efficient microbial fermentation processes to replace traditional animal-derived extraction.

The companies profiled above are not just supplying a key ingredient; they are at the forefront of biotechnological innovation, enabling advancements that enhance beauty, improve health outcomes, and push the boundaries of medical science.

Read Full Report: Global Sodium Hyaluronate Market – View in Detailed Research Report