The Global Liquiritigenin Market was valued at US$ 25.8 Million in 2025 and is projected to reach US$ 38.2 Million by 2030, growing at a Compound Annual Growth Rate (CAGR) of 8.1% during the forecast period (2024–2030). This robust growth trajectory is fueled by increasing demand for natural therapeutics, rising consumer awareness of bioactive compounds, and expanding applications in the pharmaceutical, nutraceutical, and cosmetic industries.

As the herbal medicine and functional ingredients sector expands, the spotlight turns to the key manufacturers and suppliers who are driving quality, innovation, and reliable supply chains. Liquiritigenin, a prominent bioactive flavonoid derived from licorice root (*Glycyrrhiza glabra*), is gaining significant attention for its antioxidant, anti-inflammatory, and neuroprotective properties. This blog profiles the Top 10 Companies in the Liquiritigenin Market—a strategic mix of global biotechnology firms, specialty chemical manufacturers, and research-focused suppliers shaping the future of this vital ingredient.

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Liquiritigenin Market – View in Detailed Research Report

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🔟 1. Tocris Bioscience (Bio-Techne Corporation)

Headquarters: Minneapolis, Minnesota, USA
Key Offering: High-Purity Liquiritigenin (≥98%), Research-Grade Bioactive Compounds

As part of the global life sciences leader Bio-Techne, Tocris Bioscience is a premier supplier of high-purity pharmacological tools, including liquiritigenin, for academic and pharmaceutical research. Their products are essential for drug discovery programs targeting cancer, neurological disorders, and metabolic diseases.

Innovation and Quality Initiatives:

• Rigorous quality control ensuring ≥98% purity for research reproducibility

• Comprehensive technical data and support for researchers

• Integration into large-scale biomarker and assay development projects

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9️⃣ 2. Merck KGaA (Sigma-Aldrich)

Headquarters: Darmstadt, Germany
Key Offering: Analytical Standards, Pharmaceutical Intermediates, High-Purity Liquiritigenin

Merck, operating through its Sigma-Aldrich brand, is a cornerstone of the global chemical and life science supply chain. The company offers liquiritigenin as part of its extensive portfolio of fine chemicals and natural product standards, serving R&D labs, quality control departments, and production facilities worldwide.

Innovation and Quality Initiatives:

• Global distribution network ensuring supply chain resilience

• Certified reference materials for analytical method validation

• Investment in sustainable sourcing and green chemistry principles

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8️⃣ 3. Santa Cruz Biotechnology, Inc.

Headquarters: Dallas, Texas, USA
Key Offering: Research Antibodies, Biochemicals, Natural Compounds including Liquiritigenin

Santa Cruz Biotechnology is a leading supplier of research reagents, with a strong focus on cancer research and immunology. The company provides high-quality liquiritigenin to support scientific investigations into its mechanisms of action, particularly its estrogenic and anti-proliferative effects.

Innovation and Quality Initiatives:

• Development of companion research tools (antibodies, ELISA kits) for liquiritigenin studies

• Commitment to product validation and batch-to-batch consistency

Download FREE Sample Report:
Liquiritigenin Market – View in Detailed Research Report

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7️⃣ 4. ChemFaces Biochemical Co., Ltd.

Headquarters: Wuhan, Hubei, China
Key Offering: Natural Plant Extracts, Reference Standards, Custom Synthesis of Liquiritigenin

ChemFaces specializes in the isolation, purification, and synthesis of natural products and their derivatives. The company is a key Asian supplier of liquiritigenin, offering various purities to meet the demands of the pharmaceutical, cosmetic, and nutraceutical industries.

Innovation and Quality Initiatives:

• Advanced purification technologies (e.g., preparative HPLC) for high-yield production

• Strong R&D focus on derivative compounds for enhanced bioavailability

• Competitive pricing strategy for volume buyers

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6️⃣ 5. Cayman Chemical Company

Headquarters: Ann Arbor, Michigan, USA
Key Offering: Biochemical Assays, Small Molecule Inhibitors, High-Purity Liquiritigenin

Cayman Chemical is a recognized leader in supplying bioactive small molecules for research, including a comprehensive range of flavonoids. Their liquiritigenin is widely used in academic and industrial labs studying nuclear receptor signaling (e.g., estrogen receptor beta agonism) and inflammatory pathways.

Innovation and Quality Initiatives:

• Detailed Certificate of Analysis (CoA) with comprehensive spectral data (NMR, MS)

• Collaboration with academic institutions on mechanism-of-action studies

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5️⃣ 6. Jinan Boss Chemical Industry Co., Ltd.

Headquarters: Jinan, Shandong, China
Key Offering: Bulk Plant Extracts, Pharmaceutical Intermediates, Custom Manufacturing

Jinan Boss Chemical is a major Chinese manufacturer of plant-derived active ingredients, including liquiritigenin. The company leverages China’s extensive licorice root resources to produce cost-effective, high-volume batches for the global market, serving both intermediate and finished product manufacturers.

Innovation and Quality Initiatives:

• Vertical integration from raw material sourcing to final product purification

• Scalable production processes to meet large-volume commercial orders

• Adherence to international quality standards (ISO, GMP where applicable)

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4️⃣ 7. BOC Sciences

Headquarters: Shirley, New York, USA
Key Offering: Pharmaceutical Ingredients, Biochemicals, Custom Synthesis Services

BOC Sciences provides a wide array of chemical products and services for the pharmaceutical and biotechnology sectors. Their offering includes liquiritigenin for research and development purposes, supported by strong capabilities in analytical chemistry and custom synthesis.

Innovation and Quality Initiatives:

• Flexible custom synthesis services for liquiritigenin analogs and derivatives

• Robust quality assurance protocols for pharmaceutical-grade materials

Download FREE Sample Report:
Liquiritigenin Market – View in Detailed Research Report

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3️⃣ 8. TargetMol Chemicals Inc.

Headquarters: Boston, Massachusetts, USA
Key Offering: Bioactive Compounds, Screening Libraries, Natural Products like Liquiritigenin

TargetMol specializes in providing high-quality small molecules for drug discovery and development. The company’s liquiritigenin is a key component of its natural product library, utilized by researchers for high-throughput screening and target identification, particularly in oncology and metabolic disease research.

Innovation and Quality Initiatives:

• Inclusion of liquiritigenin in targeted screening libraries (e.g., Natural Compound Library)

• Provision of detailed biological activity data and potential targets

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2️⃣ 9. Shanghai Tauto Biotech Co., Ltd.

Headquarters: Shanghai, China
Key Offering: High-Purity Natural Ingredients, Plant Extracts, API Intermediates

Shanghai Tauto Biotech is a specialist manufacturer of high-purity natural compounds for the pharmaceutical and health product industries. The company has established a reputation for reliable supply and consistent quality in the liquiritigenin market, catering to both domestic Chinese and international customers.

Innovation and Quality Initiatives:

• Focus on developing phyto-pharmaceutical grade ingredients

• Strategic partnerships with academic institutes for clinical research support

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1️⃣ 10. AdooQ BioScience

Headquarters: Irvine, California, USA
Key Offering: Inhibitors, Agonists, Biochemicals for Research

AdooQ BioScience is a supplier of innovative research chemicals, with a focus on oncology and signaling pathway modulators. The company offers liquiritigenin as a selective estrogen receptor beta (ERβ) agonist, highlighting its potential application in hormone-related research and therapeutic development.

Innovation and Quality Initiatives:

• Specialization in providing well-characterized compounds for specific biological targets

• Competitive pricing for academic and startup research communities

Get Full Report Here:
Liquiritigenin Market – View in Detailed Research Report

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🌿 Outlook: The Future of Liquiritigenin is Driven by Precision Health and Natural Solutions

The liquiritigenin market is undergoing a significant transformation. While its traditional use is well-established, the industry is now investing heavily in clinical validation, novel delivery systems, and expanded therapeutic applications. The convergence of traditional herbal knowledge with modern pharmacological research is creating unprecedented opportunities.

📈 Key Trends Shaping the Market:

• Clinical Validation Boom: Increased funding for human clinical trials to substantiate health claims for liquiritigenin in areas like menopause management, neuroprotection, and liver health.

• Rising Demand for Natural & Clean-Label Products: Consumer preference shifting away from synthetic ingredients in favor of scientifically-backed natural compounds in supplements, functional foods, and cosmeceuticals.

• Advancements in Extraction and Purification: Adoption of green extraction technologies (e.g., supercritical CO2 extraction, ultrasound-assisted extraction) to improve yield, purity, and sustainability.

• Strategic Partnerships for Supply Chain Security: Manufacturers forming long-term agreements with licorice root cultivators to ensure a sustainable and traceable raw material supply amid growing demand.

🧪 Emerging Applications Fueling Growth:

• Pharmaceuticals: Development of liquiritigenin-based drugs for cancer (particularly breast and prostate), neurodegenerative diseases (Alzheimer’s, Parkinson’s), and metabolic syndrome.

• Nutraceuticals & Functional Foods: Incorporation into dietary supplements for hormonal balance, stress relief, and antioxidant support.

• Cosmetics: Utilization in anti-aging and skin-brightening formulations due to its antioxidant and anti-inflammatory properties.

Get Full Report Here:
Liquiritigenin Market – View in Detailed Research Report

The companies profiled above are not only supplying a critical bioactive ingredient—they are actively participating in the scientific validation and commercial expansion of liquiritigenin, positioning it as a cornerstone of the future natural products and precision health economy.