The Global Biologic Excipients Market was valued at USD 2.85 Billion in 2023 and is projected to reach USD 4.51 Billion by 2030, growing at a Compound Annual Growth Rate (CAGR) of 6.8% during the forecast period (2024–2030). This robust expansion is fueled by the soaring pipeline of biologic drugs, increasing demand for advanced drug delivery systems, and stringent regulatory requirements for product stabilization and safety.

As the biopharmaceutical sector advances toward more complex therapeutics like monoclonal antibodies, vaccines, and cell and gene therapies, the critical role of high-quality excipients has never been more pronounced. In this blog, we profile the Top 10 Companies in the Biologic Excipients Industry—a select group of chemical giants, specialty ingredient suppliers, and innovators ensuring the stability, efficacy, and safety of next-generation biologic medicines.

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🔟 1. BASF Corporation

Headquarters: Ludwigshafen, Germany
Key Offering: Kolliphor® surfactants, Soluplus®, Kollicoat® polymer systems

BASF is a global leader in pharmaceutical solutions, providing a comprehensive portfolio of excipients critical for biologic formulations. Their products are essential for solubility enhancement, stabilization, and controlled release of sensitive biologic active ingredients.

Innovation Initiatives:

• Development of novel polymeric solubilizers for monoclonal antibodies

• Investment in continuous manufacturing technologies for excipient production

• Commitment to bio-based and sustainable sourcing of raw materials

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9️⃣ 2. DuPont (formerly DowDuPont)

Headquarters: Wilmington, Delaware, USA
Key Offering: Methocel™ cellulose ethers, METHOCEL™ DC, Ethocel™

DuPont’s Nutrition & Biosciences division offers a wide array of excipients trusted for their consistency and performance in biologic drug products. Their expertise is particularly valuable in creating stable formulations for injectables and lyophilized products.

Innovation Initiatives:

• Expansion of high-purity cellulose-based excipients for parenterals

• Development of excipient systems for advanced therapy medicinal products (ATMPs)

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8️⃣ 3. Roquette Frères S.A.

Headquarters: Lestrem, France
Key Offering: Pearlitol® mannitol, Lycatab® maltodextrins, Kleptose® cyclodextrins

Roquette is a leading global producer of plant-based ingredients and a major supplier of excipients derived from starch and its derivatives. The company is renowned for its high-purity sugars and polyols used extensively in lyophilization (freeze-drying) of biologics.

Innovation Initiatives:

• Pioneering work in cyclodextrin-based solubilization technologies

• Investment in green chemistry for sustainable excipient manufacturing

Download FREE Sample Report:
Biologic Excipients Market – View in Detailed Research Report

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7️⃣ 4. Ashland Global Holdings Inc.

Headquarters: Wilmington, Delaware, USA
Key Offering: Benecel™ hypromellose, Klucel™ hydroxypropylcellulose, Povidone

Ashland specializes in pharmaceutical polymers and excipients that enhance the performance and stability of biologic formulations. Their products are critical for controlling viscosity, providing film coatings, and ensuring batch-to-batch consistency.

Innovation Initiatives:

• Advanced functional polymers for biopharmaceutical applications

• Focus on excipient quality and regulatory compliance for global markets

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6️⃣ 5. Evonik Industries AG

Headquarters: Essen, Germany
Key Offering: RESOMER® biodegradable polymers, EUDRAGIT® polymers, Super-refined excipients

Evonik’s Health Care business line provides sophisticated excipient systems for advanced drug delivery. Their super-refined products are specifically designed to minimize impurities that could compromise the stability of sensitive biologic drugs.

Innovation Initiatives:

• Development of lipid-based excipients for mRNA vaccines and therapeutics

• Investment in continuous manufacturing and process intensification

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5️⃣ 6. Wacker Chemie AG

Headquarters: Munich, Germany
Key Offering: CAVAMAX® cyclodextrins, SILCRON® silica gels, VINNEX® polymer additives

Wacker is a world leader in cyclodextrin technology, providing excipients that significantly enhance the solubility and bioavailability of poorly soluble biologic compounds. Their products are essential for formulating complex molecules.

Innovation Initiatives:

• Proprietary cyclodextrin complexation technologies

• Expansion of application expertise in biologics formulation

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4️⃣ 7. Archer-Daniels-Midland Co. (ADM)

Headquarters: Chicago, Illinois, USA
Key Offering: Starches, dextrins, specialty carbohydrates

ADM leverages its agricultural processing expertise to produce a range of bio-based excipients. The company provides essential carbohydrates and starches used as stabilizers, bulking agents, and formulation aids in biologic drug products.

Innovation Initiatives:

• Development of novel plant-derived excipients with enhanced functionality

• Focus on sustainable and traceable supply chains

Download FREE Sample Report:
Biologic Excipients Market – View in Detailed Research Report

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3️⃣ 8. Colorcon Inc.

Headquarters: Harleysville, Pennsylvania, USA
Key Offering: Opadry® film coating systems, Surelease® sustained release coatings

Colorcon specializes in film coating systems and modified-release technologies that are increasingly important for biologic drug products, particularly oral solid dosage forms containing biologic agents or supporting medications.

Innovation Initiatives:

• Development of tailored coating systems for sensitive biologic formulations

• Global technical support and formulation expertise

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2️⃣ 9. FMC Corporation

Headquarters: Philadelphia, Pennsylvania, USA
Key Offering: Avicel® microcrystalline cellulose, Aquacoat® aqueous polymeric dispersions

FMC’s Health and Nutrition division is a key supplier of cellulose-based excipients that provide essential functionality in biologic drug formulations, particularly as binders, disintegrants, and stabilizers in various dosage forms.

Innovation Initiatives:

• Advanced MCC grades for direct compression of complex formulations

• Development of excipient systems for high-potency biologic drugs

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1️⃣ 10. Signet Chemical Co. Pvt. Ltd.

Headquarters: Mumbai, India
Key Offering: Specialty surfactants, emulsifiers, formulation additives

Signet Chemical has established itself as a significant player in the Asian excipients market, providing essential formulation components for the rapidly growing biologic pharmaceutical sector in emerging economies.

Innovation Initiatives:

• Expansion of product portfolio to meet evolving regulatory standards

• Strategic focus on cost-effective excipient solutions for emerging markets

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Biologic Excipients Market – View in Detailed Research Report

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🔬 Outlook: The Future of Biologic Excipients Is More Sophisticated and Specialized

The biologic excipients market is undergoing a significant transformation. As biologic drugs become more complex, the demand for high-performance, multi-functional excipients is accelerating. The industry is moving beyond traditional roles toward excipients that actively contribute to drug stability, targeted delivery, and enhanced patient compliance.

📈 Key Trends Shaping the Market:

• Rising adoption of lipid nanoparticles (LNPs) for mRNA-based therapeutics and vaccines

• Increasing demand for pre-filled syringe-compatible excipients for biologics

• Growth in continuous manufacturing requiring excipients with consistent flow properties

• Stringent regulatory scrutiny driving demand for high-purity, well-characterized excipients

Get Full Report Here:
Biologic Excipients Market – View in Detailed Research Report

The companies profiled above are not just supplying ingredients—they are enabling the biopharmaceutical revolution by providing the foundation upon which innovative biologic medicines are built. Their continued investment in research and quality assurance ensures that the medicines of tomorrow will be safer, more effective, and more accessible to patients worldwide.