The Global Plant Based Squalene Market was valued at USD 128.7 Million in 2025 and is projected to reach USD 215.8 Million by 2032, growing at a Compound Annual Growth Rate (CAGR) of 7.3% during the forecast period (2024–2030). This growth is being driven by rising demand for vegan personal care products, increasing awareness about sustainable ingredients, and the accelerating adoption of Bio-fermentation Derived Squalene solutions across cosmetics, pharmaceuticals, and nutraceutical sectors.

As the beauty and wellness industries transform toward cruelty-free and sustainable operations, the spotlight is on the key ingredient suppliers who are driving innovation, purity, and cleaner sourcing pathways. In this blog, we profile the Top 10 Companies in the Plant Based Squalene Industry—a mix of biotechnology pioneers, specialty chemical producers, and natural ingredient distributors shaping the future of global personal care and health markets.

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🔟 1. Amyris, Inc.

Headquarters: Emeryville, California, USA
Key Offering: Neossance® Squalane (Sugarcane-derived), Sustainable Emollients

Amyris is a global leader in sustainable ingredients, utilizing its proprietary Lab-to-Market™ technology platform to produce high-purity sugarcane-derived squalane. Their biofermentation process offers a consistent, scalable, and ethical alternative to traditional plant or shark-derived sources, supplying major cosmetic brands worldwide.

Sustainability Initiatives:

• Pioneering sugarcane-based biosynthesis for squalane production

• Commitment to 100% renewable carbon sourcing

• Partnerships with leading beauty and personal care brands for sustainable formulations

Download FREE Sample Report: Global Plant Based Squalene Market – View in Detailed Research Report

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9️⃣ 2. Clariant AG

Headquarters: Muttenz, Switzerland
Key Offering: Vegapure® Squalane (Olive-derived), High-Purity Plant-Based Ingredients

Clariant is a major specialty chemicals company offering high-purity, olive-derived squalane under its Vegapure® brand. Their product is renowned for its excellent moisturizing properties and is a key ingredient in premium skincare, color cosmetics, and hair care products, catering to the demand for natural and sustainable beauty solutions.

Sustainability Initiatives:

• Focus on bio-based and renewable raw materials

• Implementation of EcoTain® label for superior sustainable products

• Continuous innovation in green chemistry for cosmetic applications

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8️⃣ 3. Nucelis LLC

Headquarters: La Jolla, California, USA
Key Offering: Fermentation-derived Squalene, Sustainable Lipid Ingredients

Nucelis is a biotechnology company developing sustainable, fermentation-derived ingredients for the personal care and wellness markets. Their proprietary microbial strains are engineered to produce high-value compounds like squalene efficiently and sustainably, offering a reliable and scalable supply chain for the industry.

Sustainability Initiatives:

• Utilization of non-GMO, proprietary yeast strains for production

• Focus on creating a resilient, non-agricultural supply chain

• Development of ingredients with a lower environmental footprint

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7️⃣ 4. Kishimoto Special Liver Oil Co., Ltd.

Headquarters: Tokyo, Japan
Key Offering: Olive-derived Squalene, Botanical Squalane

Kishimoto Special Liver Oil, with a long history in marine oils, has strategically expanded into plant-based squalene to meet the growing demand for sustainable ingredients. They offer high-quality olive-derived squalene, leveraging their expertise in purification to serve the Japanese and international cosmetics markets.

Sustainability Initiatives:

• Strategic diversification from marine to plant-based sourcing

• Adherence to stringent quality control for ingredient purity

• Commitment to sustainable sourcing practices

Download FREE Sample Report: Global Plant Based Squalene Market – View in Detailed Research Report

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6️⃣ 5. Sophim

Headquarters: Peyruis, France
Key Offering: Phytosqualan® (Olive-derived Squalane), Natural Emollients

Sophim is a French company specializing in the transformation of natural raw materials into high-value ingredients for cosmetics. Their flagship product, Phytosqualan, is a fully hydrogenated olive-derived squalane prized for its stability, biocompatibility, and exceptional skin feel, making it a favorite among formulators.

Sustainability Initiatives:

• Focus on upcycling olive oil industry by-products

• Implementation of eco-friendly extraction and purification processes

• Strong commitment to the principles of green chemistry

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5️⃣ 6. The Ordinary (DECIEM)

Headquarters: Toronto, Canada
Key Offering: 100% Plant-Derived Squalane, Consumer-Facing Skincare Products

The Ordinary, a brand under DECIEM, has significantly influenced the market by popularizing plant-derived squalane directly with consumers. Their transparent marketing and accessible pricing have driven mass awareness and adoption of this ingredient, making it a staple in minimalist skincare routines globally.

Sustainability Initiatives:

• Clear labeling and consumer education on plant-based sourcing

• Commitment to cruelty-free and vegan formulations

• Focus on sustainable packaging and responsible business practices

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4️⃣ 7. Caribbean Natural Products Inc.

Headquarters: Miami, Florida, USA
Key Offering: Organic Plant-Based Squalane, Natural Oils and Butters

Caribbean Natural Products is a supplier of ethically sourced, natural ingredients for the cosmetic industry. They provide plant-based squalane, often emphasizing organic and sustainably harvested raw materials, catering to brands with a strong focus on natural and organic positioning.

Sustainability Initiatives:

• Specialization in ethically sourced and organic raw materials

• Support for sustainable agricultural practices

• Provision of ingredients that meet various eco-certifications

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3️⃣ 8. ARISTA INDUSTRIES, INC.

Headquarters: Wilton, Connecticut, USA
Key Offering: Olive Squalene, Omega-3 Oils, Specialty Lipids

ARISTA INDUSTRIES is a leading supplier of specialty oils and lipids, including high-purity olive-derived squalene. With decades of experience, they serve the nutritional, pharmaceutical, and cosmetic industries, providing ingredients that meet rigorous quality standards.

Sustainability Initiatives:

• Long-standing reputation for quality and purity in natural oils

• Strategic sourcing from reputable global suppliers

• Commitment to providing sustainable alternatives to animal-derived ingredients

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2️⃣ 9. EPF Biotek

Headquarters: Princeton, New Jersey, USA
Key Offering: Botanical Squalane, Fermentation-Derived Ingredients

EPF Biotek focuses on developing and supplying innovative, sustainable ingredients through advanced biotechnology. They are involved in producing high-purity squalane from non-animal sources, targeting the growing demand from the clean beauty and wellness sectors.

Sustainability Initiatives:

• Investment in biotechnological production methods for sustainability

• Focus on creating ingredients with minimal environmental impact

• Collaboration with brands on custom sustainable solutions

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1️⃣ 10. SynShark

Headquarters: Bremen, Germany
Key Offering: Biosynthetic Squalene, Sustainable Terpenes

SynShark is a German biotech startup pioneering the production of squalene through a proprietary fermentation process using genetically modified microorganisms. This approach aims to provide a highly pure, scalable, and completely sustainable source of squalene, independent of agricultural constraints.

Sustainability Initiatives:

• Development of a disruptive, fermentation-based production platform

• Aim to decouple squalene production from land and crop use

• Focus on creating a transparent and traceable supply chain

Get Full Report Here: Global Plant Based Squalene Market – View in Detailed Research Report

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🌍 Outlook: The Future of Plant Based Squalene Is Sustainable and Innovative

The plant-based squalene market is undergoing a significant transformation. While traditional olive oil extraction remains important, the industry is increasingly investing in biotechnological advancements, novel sourcing methods, and supply chain resilience to meet the demands of a conscious consumer base.

📈 Key Trends Shaping the Market:

• Rapid adoption of bio-fermentation for scalable and consistent production

• Regulatory support and consumer push for cruelty-free and vegan-certified ingredients

• Expansion into high-growth pharmaceutical applications, including vaccine adjuvants

• Brand-ingredient company collaborations for bespoke sustainable formulations

Get Full Report Here: Global Plant Based Squalene Market – View in Detailed Research Report

The companies listed above are not only supplying essential ingredients for global beauty and health—they’re spearheading the ethical and sustainable evolution of product formulations.