The Global Calcium Phosphate Based Ceramic Market was valued at USD 150.2 Million in 2025 and is projected to reach USD 241.8 Million by 2030, growing at a Compound Annual Growth Rate (CAGR) of 7.1% during the forecast period (2024–2030). This robust growth is fueled by an aging global population, rising prevalence of musculoskeletal disorders, increasing demand for advanced dental procedures, and significant technological advancements in bone graft substitutes and orthobiologics.

As regenerative medicine continues to redefine patient care, the role of advanced biomaterials like calcium phosphate ceramics (CPCs) becomes increasingly critical. These materials are essential for bone regeneration, offering excellent osteoconductivity and biocompatibility. In this blog, we profile the Top 10 Companies in the Calcium Phosphate Based Ceramic Industry—a group of medical device innovators, material science leaders, and healthcare pioneers shaping the future of bone and dental repair.

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🔟 1. Zimmer Biomet Holdings, Inc.

Headquarters: Warsaw, Indiana, USA
Key Offering: Collagraft® Bone Graft Matrix, OsseoTi® Porous Metals

Zimmer Biomet is a global leader in musculoskeletal healthcare, with a significant portfolio of biomaterials for orthopedic and dental applications. The company develops and markets calcium phosphate-based bone void fillers and synthetic grafts that support bone healing in various surgical procedures, from spinal fusions to joint reconstruction.

Innovation Focus:

• Development of composite matrices combining collagen and calcium phosphate

• Proprietary 3D-printing technologies for creating patient-specific porous implants

• Extensive clinical research programs to validate new biomaterial formulations

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9️⃣ 2. Stryker Corporation

Headquarters: Kalamazoo, Michigan, USA
Key Offering: HydroSet® Injectable Bone Substitute, Tritanium® Technology

Stryker’s orthobiologics division is a major force in the CPC market, offering advanced bone graft substitutes that are used in trauma, spine, and craniomaxillofacial surgeries. Their HydroSet product is a key example—an injectable, self-setting calcium phosphate cement that hardens in minutes to provide immediate structural support.

Innovation Focus:

• Injectable and moldable CPC formulations for minimally invasive procedures

• Integration of CPCs with Stryker’s digital surgery ecosystem

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8️⃣ 3. Medtronic plc

Headquarters: Dublin, Ireland
Key Offering: Mastergraft® Matrix, Infinity®-TCP

Medtronic offers a comprehensive range of spinal and orthopedic solutions, including advanced calcium phosphate-based biomaterials. Their products are designed to mimic natural bone chemistry and structure, facilitating bone growth and integration in complex spinal fusion and trauma cases.

Innovation Focus:

• Biphasic calcium phosphate composites combining HA and β-TCP

• Granular and strip formulations for tailored clinical applications

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7️⃣ 4. DSM Biomedical

Headquarters: Geleen, Netherlands
Key Offering: BiOCRYL® HA, OsSatura® BCP

DSM Biomedical specializes in high-performance biomaterials for medical devices. Their calcium phosphate ceramic offerings include hydroxyapatite (HA) and biphasic calcium phosphate (BCP) products used in dental implants, coatings for metallic implants, and standalone bone graft materials.

Innovation Focus:

• Bioactive coatings to enhance osseointegration of orthopedic implants

• Customized material solutions for medical device OEM partners

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Calcium Phosphate Based Ceramic Market – View in Detailed Research Report

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6️⃣ 5. CAM Bioceramics B.V.

Headquarters: Leiden, Netherlands
Key Offering: Customized BCP Ceramics, Injectafill®

CAM Bioceramics is a specialized developer and manufacturer of high-purity biphasic calcium phosphate ceramics. The company serves as a critical supplier to many leading medical device companies, providing tailored ceramic granules, blocks, and injectable pastes for a wide range of orthopedic and dental applications.

Innovation Focus:

• Precise control over porosity and composition for optimal bone regeneration

• Development of resorbable ceramics with controlled degradation rates

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5️⃣ 6. Berkeley Advanced Biomaterials Inc.

Headquarters: Berkeley, California, USA
Key Offering: HAp Scaffolds, Custom TCP Formulations

Berkeley Advanced Biomaterials is a leading supplier of high-purity hydroxyapatite and tricalcium phosphate raw materials and finished components. The company’s products are used in research, dental, and orthopedic applications, with a focus on quality and consistency for critical medical uses.

Innovation Focus:

• Nanocrystalline hydroxyapatite for enhanced bioactivity

• Specialized forms including powders, granules, and pre-formed scaffolds

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4️⃣ 7. SigmaGraft® (a Skeletal Kinetics LLC company)

Headquarters: Cupertino, California, USA
Key Offering: SigmaGraft® Porous Ceramic, FlexGraft® Putty

Skeletal Kinetics specializes in advanced bone graft technologies, with their SigmaGraft product line representing a significant innovation in calcium phosphate ceramics. Their unique manufacturing process creates a highly porous, interconnected structure that closely mimics natural cancellous bone.

Innovation Focus:

• Proprietary manufacturing for superior porosity and compressive strength

• Combination products incorporating CPCs with demineralized bone matrix

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3️⃣ 8. Curasan AG

Headquarters: Kleinostheim, Germany
Key Offering: Cerasorb® (β-TCP), Cerasorb M®

Curasan is a pioneer in synthetic bone regeneration materials, with their Cerasorb® product line being one of the most established pure beta-tricalcium phosphate (β-TCP) ceramics on the market. The material is fully resorbable and osteoconductive, making it suitable for a variety of dental and orthopedic bone defect fillings.

Innovation Focus:

• Pure-phase β-TCP with controlled porosity and resorption profiles

• Specialized formulations for dental and craniofacial applications

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2️⃣ 9. MIS Implants Technologies Ltd.

Headquarters: Bar Lev Industrial Park, Israel
Key Offering: BonoGen®, C-GRAFT

MIS Implants is a global dental implant company that has developed advanced calcium phosphate-based bone grafting materials to support implantology procedures. Their biomaterials division focuses on synthetic alternatives to autografts that promote predictable bone regeneration in dental applications.

Innovation Focus:

• Integration of CPCs with dental implant systems for comprehensive solutions

• Easy-to-use delivery systems for chairside bone grafting procedures

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1️⃣ 10. Granulab (M) Sdn Bhd

Headquarters: Selangor, Malaysia
Key Offering: BiOCEM, GranuMaS

Granulab is a prominent manufacturer of biomedical-grade calcium phosphate ceramics serving the Asia-Pacific region and global markets. The company produces high-quality hydroxyapatite and tricalcium phosphate products for medical and research applications, with a focus on affordable and accessible biomaterial solutions.

Innovation Focus:

• Cost-effective production of medical-grade calcium phosphates

• Expanding distribution network across emerging healthcare markets

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Calcium Phosphate Based Ceramic Market – View in Detailed Research Report

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🦴 Outlook: The Future of Calcium Phosphate Ceramics is Smarter and More Personalized

The calcium phosphate based ceramic market is undergoing a significant transformation. While traditional granules and blocks remain fundamental, the industry is rapidly advancing toward 3D-printed scaffolds, drug-eluting formulations, and patient-specific implants that promise better clinical outcomes and faster recovery times.

📈 Key Trends Shaping the Market:

• Rising adoption of 3D printing for patient-specific cranial and maxillofacial implants

• Development of smart ceramics incorporating growth factors and antibiotics

• Growing preference for synthetic bone grafts over allografts due to safety and supply consistency

• Expansion of dental implant procedures driving demand for bone augmentation materials

Get Full Report Here:
Calcium Phosphate Based Ceramic Market – View in Detailed Research Report

The companies profiled above are not only supplying critical biomaterials—they’re enabling the regenerative revolution in modern medicine, helping patients recover faster and more completely from bone injuries and defects.