The Global 2,5-Dihydroxybenzoic Acid (DHB) Market was valued at US$ 48.7 Million in 2023 and is projected to reach US$ 68.9 Million by 2030, growing at a Compound Annual Growth Rate (CAGR) of 5.1% during the forecast period (2024–2030). This expansion is primarily driven by the critical role DHB plays as a Matrix-Assisted Laser Desorption/Ionization (MALDI) mass spectrometry matrix and its increasing applications in pharmaceutical excipients and fine chemical synthesis.

As analytical techniques and pharmaceutical manufacturing become more sophisticated, the demand for high-purity chemical intermediates like 2,5-Dihydroxybenzoic Acid is accelerating. In this blog, we profile the Top 10 Companies in the 2,5-Dihydroxybenzoic Acid Industry—a diverse group of specialty chemical manufacturers, reagent suppliers, and pharmaceutical ingredient producers shaping the supply chain for this essential compound.

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🔟 10. Henan Tianfu Chemical Co., Ltd.

Headquarters: Zhengzhou, Henan, China
Key Offering: High-Purity 2,5-Dihydroxybenzoic Acid, Chemical Intermediates

Henan Tianfu Chemical is a significant Chinese manufacturer of fine chemicals and pharmaceutical intermediates. The company supplies 2,5-Dihydroxybenzoic Acid to both domestic and international markets, focusing on cost-effective production scales to serve a broad customer base.

Innovation and Market Focus:

• Large-scale production capabilities for industrial-grade chemicals
• Strong distribution network within Asia
• Focus on competitive pricing for bulk chemical orders

Download FREE Sample Report: 2,5-Dihydroxybenzoic Acid Market – View in Detailed Research Report

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9️⃣ 9. Nanjing Chemical Reagent Co., Ltd.

Headquarters: Nanjing, Jiangsu, China
Key Offering: Analytical Reagent Grade 2,5-DHB, Laboratory Chemicals

Nanjing Chemical Reagent specializes in the production of high-purity chemical reagents for laboratory and research applications. The company is a key supplier of reagent-grade 2,5-Dihydroxybenzoic Acid to academic institutions and analytical laboratories across China and neighboring regions.

Innovation and Market Focus:

• GMP-compliant manufacturing for reagent applications
• Specialization in analytical and laboratory-grade chemicals
• Strong presence in the Chinese academic and research sector

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8️⃣ 8. Anhui Sunhere Pharmaceutical Excipients Co., Ltd.

Headquarters: Huainan, Anhui, China
Key Offering: Pharmaceutical Grade 2,5-DHB, Excipient Solutions

Anhui Sunhere is a specialized manufacturer focused on pharmaceutical excipients and intermediates. The company produces 2,5-Dihydroxybenzoic Acid that meets stringent pharmacopeial standards, catering specifically to the pharmaceutical formulation sector.

Innovation and Market Focus:

• Focus on pharmaceutical-grade purity and compliance
• Strategic partnerships with API manufacturers
• Expanding portfolio of specialty excipients

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7️⃣ 7. Zhejiang Candorly Pharmaceutical Co., Ltd.

Headquarters: Taizhou, Zhejiang, China
Key Offering: High-Purity 2,5-DHB, Custom Synthesis

Zhejiang Candorly Pharmaceutical is an emerging player in the fine chemicals space, with capabilities in custom synthesis and contract manufacturing. The company offers 2,5-Dihydroxybenzoic Acid with a focus on serving the evolving needs of the pharmaceutical and biotechnology industries.

Innovation and Market Focus:

• Custom synthesis services for specialized derivatives
• Growing export operations to European and North American markets
• Investment in R&D for novel chemical entities

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6️⃣ 6. Actylis

Headquarters: Port Washington, New York, USA
Key Offering: 2,5-Dihydroxybenzoic Acid, Fine Chemicals

Actylis, formed from the combination of Aceto and OmniChem, is a global leader in the sourcing, marketing, and distribution of pharmaceutical ingredients and fine chemicals. The company provides high-quality 2,5-DHB to a diverse customer base across life sciences and industrial sectors.

Innovation and Market Focus:

• Global supply chain and logistics expertise
• Extensive portfolio of active pharmaceutical ingredients (APIs) and intermediates
• Strong regulatory support and quality assurance

Download FREE Sample Report: 2,5-Dihydroxybenzoic Acid Market – View in Detailed Research Report

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5️⃣ 5. Pharmaffiliates

Headquarters: Mumbai, Maharashtra, India
Key Offering: Analytical Reference Standards, 2,5-DHB

Pharmaffiliates is an India-based company specializing in analytical standards, impurities, and reference materials for the pharmaceutical industry. They supply high-purity 2,5-Dihydroxybenzoic Acid primarily for analytical and quality control applications.

Innovation and Market Focus:

• Specialization in pharmaceutical reference standards
• GMP/GLP compliant manufacturing and documentation
• Services supporting pharmaceutical R&D and regulatory submissions

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4️⃣ 4. Biosynth

Headquarters: Staad, Switzerland
Key Offering: High-Purity 2,5-DHB, Carbohydrates, Biochemicals

Biosynth is a leading supplier of life science reagents, biochemicals, and carbohydrate chemistry products. The company offers 2,5-Dihydroxybenzoic Acid as part of its extensive portfolio, serving research institutions and pharmaceutical companies worldwide with a focus on quality and consistency.

Innovation and Market Focus:

• Extensive catalog of biochemicals and research reagents
• Strong presence in the academic and research market
• Custom synthesis and manufacturing services

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3️⃣ 3. Spectrum Chemical Mfg. Corp.

Headquarters: New Brunswick, New Jersey, USA
Key Offering: USP, NF, FCC, Analytical Reagent Grades of 2,5-DHB

Spectrum Chemical is a global manufacturer and supplier of high-purity fine chemicals. The company offers 2,5-Dihydroxybenzoic Acid in various grades, including USP and analytical reagent specifications, making it a trusted supplier for pharmaceutical, food, and laboratory applications.

Innovation and Market Focus:

• Rigorous quality control and multiple compliance certifications (cGMP, ISO)
• Broad product portfolio with extensive documentation
• Global distribution network serving diverse industries

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2️⃣ 2. Otto Chemie Pvt. Ltd.

Headquarters: Mumbai, Maharashtra, India
Key Offering: Laboratory Chemicals, 2,5-Dihydroxybenzoic Acid

Otto Chemie is a prominent Indian manufacturer and supplier of laboratory chemicals and bio-chemicals. The company is a key source for 2,5-Dihydroxybenzoic Acid in the Asian market, providing products for research, pharmaceutical development, and industrial applications.

Innovation and Market Focus:

• Focus on the Indian and South Asian chemical markets
• Competitive pricing strategy for research and industrial customers
• Expanding export operations to global markets

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1️⃣ 1. Molekula Group

Headquarters: Newcastle Upon Tyne, United Kingdom
Key Offering: High-Purity 2,5-DHB, Rare Chemicals, Custom Synthesis

Molekula Group is a global specialty chemical company known for supplying rare, high-purity, and difficult-to-source chemical compounds. As a leading supplier of 2,5-Dihydroxybenzoic Acid, the company serves advanced research, pharmaceutical development, and specialty manufacturing sectors with a strong emphasis on quality and customer service.

Innovation and Market Focus:

• Specialization in rare and high-purity organic compounds
• Strong technical support and custom synthesis capabilities
• Global distribution with a focus on research and pharmaceutical industries

Get Full Report Here: 2,5-Dihydroxybenzoic Acid Market – View in Detailed Research Report

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🔬 Outlook: The Future of 2,5-Dihydroxybenzoic Acid Is Diversified and High-Tech

The 2,5-Dihydroxybenzoic Acid market is experiencing a significant transformation. While its traditional role as a MALDI matrix remains fundamental, new applications in pharmaceuticals and material science are creating fresh growth avenues. The industry is investing in advanced purification technologies, scalable synthesis routes, and application-specific formulations.

📈 Key Trends Shaping the Market:

• Growing demand for ultra-high-purity grades for advanced mass spectrometry applications
• Exploration of DHB derivatives for novel pharmaceutical formulations
• Increasing outsourcing of fine chemical synthesis by major pharmaceutical companies
• Stringent regulatory standards driving investments in quality control and documentation

The companies listed above are not only supplying a critical chemical intermediate—they’re enabling scientific discovery and pharmaceutical innovation across the globe.

Get Full Report Here: 2,5-Dihydroxybenzoic Acid Market – View in Detailed Research Report