The global Sialic Acid Powder market was valued at USD 210 Million in 2023 and is projected to reach USD 380 Million by 2030, growing at a Compound Annual Growth Rate (CAGR) of 8.9% during the forecast period (2024–2030). This significant growth is propelled by rising consumer awareness of cognitive health, expanding applications in infant nutrition and pharmaceuticals, and advancements in biotechnological production methods.

As the nutraceutical and pharmaceutical industries increasingly recognize the critical role of sialic acid in human health, the demand for high-purity sialic acid powder is surging. In this blog, we profile the Top 10 Companies in the Sialic Acid Powder Industry—a combination of established bio-chemical firms and innovative specialists driving the market forward with quality, research, and scalable production.

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🔟 1. Oryza Oil & Fat Chemical Co., Ltd.

Headquarters: Aichi Prefecture, Japan
Key Offering: High-Purity Sialic Acid Powder (N-Acetylneuraminic Acid)

Oryza is a prominent Japanese manufacturer specializing in the extraction and purification of high-value compounds from natural sources. The company is a leading supplier of sialic acid powder, primarily derived from avian egg yolks, known for its stringent quality control and high bioactivity.

Innovation and Production Focus:

• Proprietary extraction and purification technologies

• Focus on pharmaceutical and nutraceutical grade purity

• Strong R&D pipeline for new applications in neurology and immunology

Download FREE Sample Report: Sialic Acid Powder Market – View in Detailed Research Report

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9️⃣ 2. Sanyo Fine Co., Ltd.

Headquarters: Osaka, Japan
Key Offering: Food Grade and Pharmaceutical Grade Sialic Acid

Sanyo Fine is a key player in the fine chemicals sector, with a dedicated focus on saccharides and derivatives. The company produces sialic acid powder that meets rigorous international standards for use in infant formula, dietary supplements, and clinical research.

Innovation and Production Focus:

• Advanced chromatographic purification processes

• Expanding production capacity to meet global demand

• Strategic partnerships with global nutrition brands

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8️⃣ 3. Cabio Biotech (Wuhan) Co., Ltd.

Headquarters: Wuhan, Hubei, China
Key Offering: Sialic Acid (NANA) from fermentation

Cabio Biotech is a leading Chinese biotech company that utilizes microbial fermentation—a sustainable and scalable alternative to animal-derived extraction—to produce sialic acid. This positions them as a key supplier for the vegan and allergen-free market segments.

Innovation and Production Focus:

• Pioneering microbial fermentation technology for sialic acid production

• Cost-effective manufacturing for high-volume applications

• Focus on securing regulatory approvals in North America and Europe

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7️⃣ 4. Higrand Biotech Co., Ltd

Headquarters: Xinxiang, Henan, China
Key Offering: Sialic Acid Powder for Food and Pharma

Higrand Biotech specializes in the research, development, and production of bio-active ingredients. The company is a significant manufacturer of sialic acid, offering various grades to cater to the diverse needs of the food, health product, and pharmaceutical industries.

Innovation and Production Focus:

• Integrated production from raw material to finished product

• Investment in R&D for novel sialic acid derivatives

• Expanding global distribution network

Download FREE Sample Report: Sialic Acid Powder Market – View in Detailed Research Report

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6️⃣ 5. Ingredia Nutritional

Headquarters: Arras, France
Key Offering: Milk-derived bioactive ingredients, including sialic acid fractions

Ingredia Nutritional, a global dairy-ingredient leader, provides specialized milk fractions rich in bioactive compounds. While not a pure sialic acid powder manufacturer, it is a crucial supplier of lactoferrin and other milk glycoproteins that are key sources of sialic acid for the infant nutrition industry.

Innovation and Production Focus:

• Expertise in isolating and purifying milk-based bioactives

• Strong presence in the premium infant formula market

• Sustainable and traceable dairy sourcing

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5️⃣ 6. Zhejiang Nature Biotechnology Co., Ltd.

Headquarters: Hangzhou, Zhejiang, China
Key Offering: Plant-derived and synthetic bioactive compounds

Zhejiang Nature Biotechnology is an innovative company exploring alternative sources for high-value ingredients. It is involved in research to produce sialic acid analogues and enhance the bioavailability of sialylated compounds for functional food applications.

Innovation and Production Focus:

• R&D into plant cell culture for sialic acid production

• Development of synergistic ingredient blends

• Focus on cost-competitive production methods

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4️⃣ 7. GlycoMatrix (a division of Jennewein Biotechnologie)

Headquarters: Rheinbreitbach, Germany
Key Offering: Human Milk Oligosaccharides (HMOs) and related compounds

While Jennewein is renowned for HMOs, its technological platform for complex carbohydrate synthesis positions it as a potential future leader in sialic acid and sialylated oligosaccharides. Its expertise is critical for developing the next generation of infant nutrition products that closely mimic human milk.

Innovation and Production Focus:

• World-leading enzymatic synthesis technology for carbohydrates

• Production of sialyllactose, a key sialic acid-containing HMO

• Strong IP portfolio and scientific collaborations

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3️⃣ 8. DSM Nutritional Products

Headquarters: Kaiseraugst, Switzerland
Key Offering: Broad portfolio of vitamins, nutrients, and health ingredients

DSM is a global science-based company active in health, nutrition, and bioscience. Through its extensive work in early-life nutrition and dietary supplements, DSM is a major end-user and influencer in the sialic acid value chain, often partnering with specialized producers to incorporate sialic acid into its finished product formulations.

Innovation and Production Focus:

• Application development for cognitive and immune health solutions

• Investment in precision fermentation and biotechnology

• Commitment to sustainability across its supply chain

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2️⃣ 9. BASF SE

Headquarters: Ludwigshafen, Germany
Key Offering: Chemicals, nutrition, and health ingredients

As one of the world’s largest chemical companies, BASF’s nutrition and health division has the capacity and R&D resources to be a significant player in high-purity ingredients. Its capabilities in chemical synthesis and fermentation make it a potential key manufacturer or strategic partner for sialic acid production at scale.

Innovation and Production Focus:

• Strong capabilities in industrial biotechnology

• Global reach and robust quality assurance systems

• Focus on developing integrated solutions for customers

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1️⃣ 10. Kyowa Hakko Bio Co., Ltd.

Headquarters: Tokyo, Japan
Key Offering: Amino acids, nucleotides, and other bioactive substances

Kyowa Hakko Bio, a member of the Kirin Group, is a pioneer in fermentation technology. With its expertise in producing a wide range of bio-chemicals, the company has the foundational technology to produce sialic acid via fermentation, positioning it as an important and reliable supplier for the pharmaceutical and nutraceutical industries.

Innovation and Production Focus:

• Decades of experience in microbial fermentation

• Strong focus on quality and regulatory compliance

• Strategic focus on health-benefit ingredients

Get Full Report Here: Sialic Acid Powder Market – View in Detailed Research Report

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🧠 Outlook: The Future of Sialic Acid Powder is Smart and Scalable

The sialic acid powder market is evolving from a niche ingredient to a mainstream bioactive compound. While traditional extraction methods from natural sources like eggs dominate, the industry is rapidly investing in biotechnological production to ensure scalability, sustainability, and cost-effectiveness.

📈 Key Trends Shaping the Market:

• Shift from animal-derived to microbial fermentation-based production

• Growing scientific validation of sialic acid’s benefits for brain health and immunity

• Expansion into new applications such as skincare and veterinary nutrition

• Increased regulatory clarity and acceptance in major markets worldwide

Get Full Report Here: Sialic Acid Powder Market – View in Detailed Research Report

The companies listed above are not only supplying a critical ingredient—they are at the forefront of scientific innovation, unlocking the full potential of sialic acid for human health and wellness.